Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Johanna von Gerichten"'
Autor:
Joshua Millar, Luke Gibbons, Catia Costa, Ella Schneider, Johanna von Gerichten, Melanie J. Bailey, Susan Campbell, Catherine Duckett, Sarah Doyle, Laura M. Cole
Publikováno v:
Analytica, Vol 4, Iss 3, Pp 264-279 (2023)
The metallome has been involved in the pathological investigation into ocular tissue for decades; however, as technologies advance, more information can be ascertained from individual tissue sections that were not previously possible. Herein, a demon
Externí odkaz:
https://doaj.org/article/cd9d9cdaae364613b307ba81de363f2a
Autor:
Johanna von Gerichten, Annette L. West, Nicola A. Irvine, Elizabeth A. Miles, Philip C. Calder, Karen A. Lillycrop, Graham C. Burdge, Barbara A. Fielding
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Immune function changes across the life stages; for example, senior adults exhibit a tendency towards a weaker cell-mediated immune response and a stronger inflammatory response than younger adults. This might be partly mediated by changes in oxylipi
Externí odkaz:
https://doaj.org/article/49889a51f4af4d36bcb198ad532c0087
Autor:
Anthony Onoja, Johanna von Gerichten, Holly-May Lewis, Melanie J. Bailey, Debra J. Skene, Nophar Geifman, Matt Spick
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 18, p 14371 (2023)
The global COVID-19 pandemic resulted in widespread harms but also rapid advances in vaccine development, diagnostic testing, and treatment. As the disease moves to endemic status, the need to identify characteristic biomarkers of the disease for dia
Externí odkaz:
https://doaj.org/article/97b1c69c8d38464185e59e35ca08cdb7
Autor:
Annette L. West, Johanna von Gerichten, Nicola A. Irvine, Elizabeth A. Miles, Karen A. Lillycrop, Philip C. Calder, Barbara A. Fielding, Graham C. Burdge
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
IntroductionImmune function changes across the life course; the fetal immune system is characterised by tolerance while that of seniors is less able to respond effectively to antigens and is more pro-inflammatory than in younger adults. Lipids are in
Externí odkaz:
https://doaj.org/article/adc829dcb3514a6e9c3b6ff1a052bb6a
Autor:
Johanna von Gerichten, Dominic Lamprecht, Lukáš Opálka, Daphnée Soulard, Christian Marsching, Robert Pilz, Valentin Sencio, Silke Herzer, Bruno Galy, Viola Nordström, Carsten Hopf, Hermann-Josef Gröne, François Trottein, Roger Sandhoff
Publikováno v:
Journal of Lipid Research, Vol 60, Iss 11, Pp 1892-1904 (2019)
The glycosphingolipid, α-galactosylceramide (αGalCer), when presented by CD1d on antigen-presenting cells, efficiently activates invariant natural killer T (iNKT) cells. Thereby, it modulates immune responses against tumors, microbial and viral inf
Externí odkaz:
https://doaj.org/article/916935eb800d4a97908209492b1d14ed
Autor:
Johanna von Gerichten, Annette L. West, Nicola A. Irvine, Elizabeth A. Miles, Philip C. Calder, Karen A. Lillycrop, Barbara A. Fielding, Graham C. Burdge
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Longer-chain polyunsaturated fatty acids (LCPUFAs) ≥20 carbons long are required for leukocyte function. These can be obtained from the diet, but there is some evidence that leukocytes can convert essential fatty acids (EFAs) into LCPUFAs. We used
Externí odkaz:
https://doaj.org/article/b8a2cba2a0af44c8b88383c9394d7c7a
Autor:
Matt Spick, Amy Campbell, Ivona Baricevic-Jones, Johanna von Gerichten, Holly-May Lewis, Cecile F. Frampas, Katie Longman, Alexander Stewart, Deborah Dunn-Walters, Debra J. Skene, Nophar Geifman, Anthony D. Whetton, Melanie J. Bailey
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 20, p 12079 (2022)
Treatments for COVID-19 infections have improved dramatically since the beginning of the pandemic, and glucocorticoids have been a key tool in improving mortality rates. The UK’s National Institute for Health and Care Excellence guidance is for tre
Externí odkaz:
https://doaj.org/article/8dac2462bc9743d19bd440d3df7a5ac9
Autor:
Johanna von Gerichten, Kerstin Schlosser, Dominic Lamprecht, Ivan Morace, Matthias Eckhardt, Dagmar Wachten, Richard Jennemann, Hermann-Josef Gröne, Matthias Mack, Roger Sandhoff
Publikováno v:
Journal of Lipid Research, Vol 58, Iss 6, Pp 1247-1258 (2017)
Mammals synthesize, cell-type specifically, the diastereomeric hexosylceramides, β-galactosylceramide (GalCer) and β-glucosylceramide (GlcCer), which are involved in several diseases, such as sphingolipidosis, diabetes, chronic kidney diseases, or
Externí odkaz:
https://doaj.org/article/c86c3de3fab0410f9a9efffb263caea3
Autor:
Christophe Paget, Shenglou Deng, Daphnée Soulard, David A Priestman, Silvia Speca, Johanna von Gerichten, Anneliese O Speak, Ashish Saroha, Yael Pewzner-Jung, Anthony H Futerman, Thierry Mallevaey, Christelle Faveeuw, Xiaobo Gu, Frances M Platt, Roger Sandhoff, François Trottein
Publikováno v:
PLoS Biology, Vol 17, Iss 3, p e3000169 (2019)
CD1d-restricted invariant natural killer T (iNKT) cells represent a heterogeneous population of lipid-reactive T cells that are involved in many immune responses, mediated through T-cell receptor (TCR)-dependent and/or independent activation. Althoug
Externí odkaz:
https://doaj.org/article/8a14153a2b874fd7bf923e13b9a85947
Autor:
Silke Herzer, Cassidy Hagan, Johanna von Gerichten, Vanessa Dieterle, Bogdan Munteanu, Roger Sandhoff, Carsten Hopf, Viola Nordström
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 11 (2018)
Alzheimer’s disease (AD) is characterized by progressive neurodegeneration and a concomitant loss of synapses and cognitive abilities. Recently, we have proposed that an alteration of neuronal membrane lipid microdomains increases neuronal resistan
Externí odkaz:
https://doaj.org/article/a7ca70e173f3433f8ff31e56a3abc602