Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Johanna Wittreich"'
Autor:
W. He, M. G. Murphy, Johanna Wittreich, Barry J. Gertz, W. M. Polvino, David R. Clemmons, L. M. Plunkett
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 83:320-325
The reversal of diet-induced negative nitrogen balance by GH suggests a possible therapeutic role for GH treatment in catabolic patients. A double-blind, randomized, placebo-controlled, two-period cross-over study was designed to investigate whether
Autor:
Stephen H. Schneider, Barry J. Gertz, Michael O. Thorner, Susan E. Kirk, Suzan S. Pezzoli, D Krupa, James R. Seibold, Johanna Wittreich, Mark L. Hartman
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 82:1154-1159
GH secretion and the response to GH secretagogues are significantly diminished in obese individuals. Previous studies have shown that L-692,429 (L), a nonpeptide mimetic of GH-releasing peptide, selectively stimulates GH release in normal young men a
Autor:
Timothy Mant, Timothy V Olah, Michael Stepanavage, Johanna Wittreich, Haiyung Cheng, Barry J. Gertz, Mark Edwards, David G. Sciberras, Polvino William J
Publikováno v:
British Journal of Clinical Pharmacology. 43:49-54
Aim We evaluated the pharmacokinetics and pharmacodynamics of oral MK-462 in comparison with oral sumatriptan in healthy male volunteers. Methods Sixteen healthy male volunteers were studied in a rising, single dose, alternating panel design with eig
Publikováno v:
American Journal of Ophthalmology. 113:638-644
In this double-masked study, we randomly assigned 488 patients with clinical signs of acute bacterial conjunctivitis or blepharitis, or both, to treatment with either norfloxacin ophthalmic solution 0.3% (245) or gentamicin ophthalmic solution 0.3% (
Autor:
Lars-Olof Eriksson, Sergio Poli, Daniel Campos, Jorge Martinez-Cedillo, Conrado Vogel, Aura Erazo, Alexandra D. Carides, Barry J. Gertz, Rick R. Reinhardt, Johanna Wittreich, Carlos Carracedo, José Rodrigues Pereira
Publikováno v:
Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 19(6)
PURPOSE: The NK1-receptor antagonist MK-869 (L-754,030) has demonstrated antiemetic activity in humans receiving chemotherapy. Objectives of the present trial included the first assessment of oral MK-869 plus dexamethasone compared with a 5HT3 antago
Autor:
Donald R. Mehlisch, Arturo G. Porras, Inge De Lepeleire, Johanna Wittreich, Elliot W. Ehrich, Barry J. Gertz, Anne Van Hecken, Wei-ying Yuan, Paul J. De Schepper, Denis Riendeau, James R. Seibold, Aimee Dallob
Publikováno v:
Clinical pharmacology and therapeutics. 65(3)
Background Nonsteroidal anti-inflammatory drugs (NSAIDs) such as aspirin, ibuprofen, and indomethacin (INN, indometacin) inhibit both the constitutive (COX-1) and inducible (COX-2) isoforms of cyclooxygenase. The induction of COX-2 after inflammatory
Autor:
K Christie, I James, D Krupa, Barry J. Gertz, L Yogendran, K Bador, Johanna Wittreich, David G. Sciberras
Publikováno v:
The Journal of clinical endocrinology and metabolism. 79(3)
The reversal of glucocorticoid-induced negative nitrogen balance by GH supports a possible therapeutic role for GH treatment in patients receiving these catabolic steroids. A GH secretagogue might be of similar utility. However, stimulated GH secreti
Autor:
D Krupa, Johanna Wittreich, J R Seibold, S H Schneider, Jeffrey S. Barrett, Barry J. Gertz, R Eisenhandler
Publikováno v:
The Journal of clinical endocrinology and metabolism. 77(5)
L-692,429, a substituted benzolactam, is a novel nonpeptide mimic of the GH secretagogue, GH-releasing peptide-6. The safety and GH secretory activity of L-692,429 (0.001-1.0 mg/kg, i.v.) were investigated in 24 healthy nonobese young (18-26 yr old)