Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Johanna Walther"'
Autor:
Johanna Walther, Danny Wilbie, Vincent S. J. Tissingh, Mert Öktem, Heleen van der Veen, Bo Lou, Enrico Mastrobattista
Publikováno v:
Pharmaceutics, Vol 14, Iss 1, p 213 (2022)
The CRISPR-Cas9 system is an emerging therapeutic tool with the potential to correct diverse genetic disorders. However, for gene therapy applications, an efficient delivery vehicle is required, capable of delivering the CRISPR-Cas9 components into t
Externí odkaz:
https://doaj.org/article/ea9ccfd5fe4c4ad8884b10d3f129f281
Autor:
Hassan Javanbakht, Henrik Mueller, Johanna Walther, Xue Zhou, Anaïs Lopez, Thushara Pattupara, Julie Blaising, Lykke Pedersen, Nanna Albæk, Malene Jackerott, Tianlai Shi, Corinne Ploix, Wouter Driessen, Robert Persson, Jacob Ravn, John A.T. Young, Søren Ottosen
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 11, Iss C, Pp 441-454 (2018)
Chronic hepatitis B infection (CHB) is an area of high unmet medical need. Current standard-of-care therapies only rarely lead to a functional cure, defined as durable hepatitis B surface antigen (HBsAg) loss following treatment. The goal for next ge
Externí odkaz:
https://doaj.org/article/1962d4b211f2443bb9955ca1ed51da8a
Autor:
Erik R. Hebels, Felix Bindt, Johanna Walther, Michiel van Geijn, Jimmy Weterings, Qizhi Hu, Claudio Colombo, Rob Liskamp, Cristianne Rijcken, Wim E. Hennink, Tina Vermonden
Publikováno v:
Biomacromolecules.
Polymeric micelles (PMs) are promising platforms for enhanced tissue targeting of entrapped therapeutic agents. Strategies to circumvent premature release of entrapped drugs include cross-linking of the micellar core as well as covalent attachment of
Autor:
Lykke Pedersen, Robert Persson, Corinne Ploix, Xue Zhou, John A. T. Young, Thushara Pattupara, Hassan Javanbakht, Tianlai Shi, Johanna Walther, Julie Elisabeth Françoise Blaising, Henrik Mueller, Wouter H. P. Driessen, Nanna Albæk, Jacob Ravn, Anaïs Lopez, Søren Ottosen, Malene Jackerott
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 11, Iss C, Pp 441-454 (2018)
Molecular Therapy. Nucleic Acids
Molecular Therapy. Nucleic Acids
Chronic hepatitis B infection (CHB) is an area of high unmet medical need. Current standard-of-care therapies only rarely lead to a functional cure, defined as durable hepatitis B surface antigen (HBsAg) loss following treatment. The goal for next ge
Autor:
Souphalone Luangsay, Jitao David Zhang, Philipp Tropberger, Maura Dandri, Guido Steiner, Roland Schmucki, Giorgio Ottaviani, Song Yang, Anaïs Lopez, Tomas Racek, Steffen Wildum, Erich Kueng, Tassilo Volz, John A. T. Young, Hassan Javanbakht, Gianna Rapp, Neil Parrott, Wenzhe Lu, Xue Zhou, Henrik Mueller, Johanna Walther, Marc Lütgehetmann, Jean-Christophe Hoflack, Floriane Point
Publikováno v:
Journal of Hepatology. 68:412-420
Background & Aims The hallmarks of chronic HBV infection are a high viral load (HBV DNA) and even higher levels (>100-fold in excess of virions) of non-infectious membranous particles containing the tolerogenic viral S antigen (HBsAg). Currently, sta
Publikováno v:
Journal of Virology. 88:8201-8212
The genus beta human papillomaviruses (beta HPVs) cause cutaneous lesions and are thought to be involved in the initiation of some nonmelanoma skin cancers (NMSCs), particularly in patients with the genetic disorder epidermodysplasia verruciformis (E
Autor:
Johanna Walther
Publikováno v:
Zeitschrift für Pädagogik und Theologie. 13:285-301
Publikováno v:
Journal of Clinical Investigation. 22:471-485
Autor:
Sandrine Simon, Nicole A. Kratochwil, Johanna Walther, Christoph Funk, Claudia McGinnis, Aynur Ekiciler, Thierry Lavé, Miriam Triyatni, Christophe Meille, Isabelle Walter, Neil Parrott, Florian Klammers, Birgit Molitor, Brian Leonard, Stephen Fowler, Franz Schuler, Hassan Javanbakht
Publikováno v:
The AAPS Journal. 19(2):534-550
Early prediction of human clearance is often challenging, in particular for the growing number of low-clearance compounds. Long-term in vitro models have been developed which enable sophisticated hepatic drug disposition studies and improved clearanc
Autor:
Dieter Vetter, Johanna Walther
Publikováno v:
Zeitschrift für die Alttestamentliche Wissenschaft. 83