Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Johanna Virri"'
Autor:
Richard D. Guyer, Heikki Vanharanta, Jukka Tolonen, Tapio Rytömaa, Johanna Virri, Erkki Karaharju, Mats Grönblad
Publikováno v:
European Spine Journal. 15:588-596
Degenerated intervertebral disc has lost its normal architecture, and there are changes both in the nuclear and annular parts of the disc. Changes in cell shape, especially in the annulus fibrosus, have been reported. During degeneration the cells be
Publikováno v:
European Spine Journal. 11:452-458
The oncoproteins c-Fos and c-Jun create a transcriptional site early response activating protein (AP-1) mediating the regulation of gene expression in response to extracellular signalling by, for example, cytokines. These proteins are important in th
Publikováno v:
European Spine Journal. 11:447-451
Mechanical compression and biochemical influences, e.g. by various inflammatory cells and mediators, have been suggested to be involved in the pathophysiology of sciatica. In addition, it has been suggested, but so far not clearly demonstrated, that
Publikováno v:
European Spine Journal. 10:172-176
Transforming growth factor beta (TGF-beta) is a potent inducer of angiogenesis and fibrogenesis. There is presently little information about the pathophysiological function of TGF-beta in herniated disc tissue. In order to analyze the cellular role a
Publikováno v:
Spine. 25:2803-2807
STUDY DESIGN Possible statistically significant relationships between inflammatory cells and either motor weakness or straight leg raising were determined. OBJECTIVES To look for any clinically relevant links between inflammatory cells in disc hernia
Autor:
Johanna Virri, M. Luukkonen, Olavi Airaksinen, Aklilu Habtemariam, Erkki Karaharju, Mats Grönblad, Sakari Savolainen, Veli Turunen
Publikováno v:
European Spine Journal. 7:387-393
Phospholipase A2 (PLA2) has been suggested to be present in herniated disc tissue and it could possibly be involved in sciatica/ discogenic back pain mechanisms. In the present study the occurrence of two different phospholipase A2 enzymes, (1) low m
Publikováno v:
Spine. 23:2159-2165
STUDY DESIGN: Herniated lumbar disc specimens were obtained from patients undergoing surgical discectomy for persistent radicular pain (radiculopathy) and stained for inflammatory cells to determine their occurrence in relation to the duration of rad
Autor:
Allison M. Kaigle, Johanna Virri, Sten Holm, Mats Grönblad, Aklilu Habtemariam, Erkki Karaharju
Publikováno v:
Spine. 23:524-529
Study design Inflammatory cells were studied by indirect immunocytochemistry in experimental full-thickness anulus fibrosus lesions in pigs. Objectives First, to determine the occurrence, by immunocytochemistry, of T lymphocytes and macrophages in ex
Publikováno v:
European Spine Journal. 6:63-69
Angiogenesis is essential in tissue growth and regeneration. There are several factors that are able to stimulate vascular endothelial cell growth, including platelet-derived growth factor (PDGF) and vascular endothelial growth factor (VEGF). Disc he
Autor:
Martti Ruuskanen, Erkki Karaharju, Johanna Virri, Tove Palmgren, Johanna Savikko, Mats Grönblad, Seppo Seitsalo
Publikováno v:
Spine. 21:1856-1863
Study design Ninety disc herniations removed during surgery were studied by immunocytochemistry, using two different endothelial cell markers, to study the prevalence, morphology, and topography of blood vessels in disc herniations. Objectives To inc