Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Johanna Villarreal"'
Publikováno v:
iScience, Vol 27, Iss 6, Pp 110152- (2024)
Summary: The mouse epididymis is a long tubule connecting the testis to the vas deferens. Its primary functions are to mature spermatozoa into motile and fertile cells and to protect them from pathogens that ascend the male tract. We previously demon
Externí odkaz:
https://doaj.org/article/ba88ca6aa0d94f4a98537c517fb04e0a
Autor:
Jon J. McCord, Minal Engavale, Elahe Masoumzadeh, Johanna Villarreal, Britney Mapp, Michael P. Latham, Peter A. Keyel, R. Bryan Sutton
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-13 (2022)
Biophysical, structural, and functional characterization of Dnase1L3 reveals differences in DNA binding and degradation mechanisms between Dnase1 and Dnase1L3 facilitated by Dnase1L3’s intrinsically disordered C-terminal domain.
Externí odkaz:
https://doaj.org/article/b5dde99e64814032bb179e63a3fbf02f
Autor:
Shan Qi, Javier Mota, Siu-Hong Chan, Johanna Villarreal, Nan Dai, Shailee Arya, Robert A Hromas, Manjeet K Rao, Ivan R Corrêa Jr, Yogesh K Gupta
Publikováno v:
eLife, Vol 11 (2022)
Methyltransferase like-3 (METTL3) and METTL14 complex transfers a methyl group from S-adenosyl-L-methionine to N6 amino group of adenosine bases in RNA (m6A) and DNA (m6dA). Emerging evidence highlights a role of METTL3-METTL14 in the chromatin conte
Externí odkaz:
https://doaj.org/article/f4794168c2784b479a677f7a2e4a2a3c
Autor:
Minal Engavale, Colton J. Hernandez, Angelica Infante, Tanya LeRoith, Elliott Radovan, Lauryn Evans, Johanna Villarreal, Christopher M. Reilly, R. Bryan Sutton, Peter A. Keyel
Publikováno v:
bioRxiv
Systemic Lupus Erythematosus (SLE) is a chronic autoimmune disease caused by environmental factors and loss of key proteins. One such protein is a serum endonuclease secreted by macrophages and dendritic cells, Dnase1L3. Loss of Dnase1L3 causes pedia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::937d5f8772081ec4326a9660e59b4b30
https://doi.org/10.1101/2023.04.17.537232
https://doi.org/10.1101/2023.04.17.537232
Autor:
Javier Mota, Shan Qi, Siu-Hong Chan, Johanna Villarreal, Nan Dai, Shailee Arya, Robert A Hromas, Manjeet K Rao, Ivan R Corrêa Jr, Yogesh K Gupta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0af79273bba51048c2ff37f71031e585
https://doi.org/10.7554/elife.67150.sa2
https://doi.org/10.7554/elife.67150.sa2
Investigating Dnase1L3's role in inflammation and redesigning the enzyme to be used as a therapeutic
Autor:
Johanna Villarreal, Jon J. McCord, Minal Engavale, Elliot Radovan, Peter Keyel, Roger B. Sutton
Publikováno v:
Biophysical Journal. 122:331a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::edfdf0145c77217b1e3fe9413eae5816
https://doi.org/10.1016/j.bpj.2022.11.1848
https://doi.org/10.1016/j.bpj.2022.11.1848
Autor:
Shan, Qi, Javier, Mota, Siu-Hong, Chan, Johanna, Villarreal, Nan, Dai, Shailee, Arya, Robert A, Hromas, Manjeet K, Rao, Ivan R, Corrêa, Yogesh K, Gupta
Publikováno v:
eLife. 11
Methyltransferase like-3 (METTL3) and METTL14 complex transfers a methyl group from
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b24bd0fec4b09536e633f5ecff7a6f84
https://pubmed.ncbi.nlm.nih.gov/35060905
https://pubmed.ncbi.nlm.nih.gov/35060905
Autor:
Johanna Villarreal, Jon J. McCord, Minal Engavale, Britney Mapp, Peter Keyel, Roger B. Sutton
Publikováno v:
Biophysical Journal. 121:47a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::32b624049ba060f9083763199d5c2244
https://doi.org/10.1016/j.bpj.2021.11.2484
https://doi.org/10.1016/j.bpj.2021.11.2484
Autor:
Johanna Villarreal, Mei Qiao, Greco Hernández, Caihong Yi, Dmitri N. Ivanov, Mitzli X. Velasco, Luiz O. F. Penalva, Zhonghua Wang, Matthew J. Hart, Yogesh K. Gupta, Christopher G. Hubert, Soni Kaundal, Guiming Li
Publikováno v:
RNA Biology. 15:1420-1432
RNA binding proteins have emerged as critical oncogenic factors and potential targets in cancer therapy. In this study, we evaluated Musashi1 (Msi1) targeting as a strategy to treat glioblastoma (GBM); the most aggressive brain tumor type. Msi1 expre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5b15bbc6bd07a5f08cf6b274f78971d
https://doi.org/10.1080/15476286.2018.1539607
https://doi.org/10.1080/15476286.2018.1539607
Autor:
Johanna Villarreal, Diane E. Cabelli, Ahmad Galaleldeen, Ryan L. Peterson, Valeria C. Culotta, P. John Hart, Alexander B. Taylor
Publikováno v:
Journal of Biological Chemistry. 291:20911-20923
In eukaryotes the bimetallic Cu/Zn superoxide dismutase (SOD) enzymes play important roles in the biology of reactive oxygen species by disproportionating superoxide anion. Recently, we reported that the fungal pathogen Candida albicans expresses a n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0bb539e8ce3d60a4c3aab8c455e4e1a
https://doi.org/10.1074/jbc.m116.748251
https://doi.org/10.1074/jbc.m116.748251