Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Johanna Viiliäinen"'
Autor:
Alena Malyukova, Mari Lahnalampi, Ton Falqués-Costa, Petri Pölönen, Mikko Sipola, Juha Mehtonen, Susanna Teppo, Karen Akopyan, Johanna Viiliainen, Olli Lohi, Anna K. Hagström-Andersson, Merja Heinäniemi, Olle Sangfelt
Publikováno v:
Genome Biology, Vol 25, Iss 1, Pp 1-38 (2024)
Abstract Background Targeted therapies exploiting vulnerabilities of cancer cells hold promise for improving patient outcome and reducing side-effects of chemotherapy. However, efficacy of precision therapies is limited in part because of tumor cell
Externí odkaz:
https://doaj.org/article/89499d14af9b44a5bde5f230fc540a77
Autor:
Andrä Brunner, Aldwin Suryo Rahmanto, Henrik Johansson, Marcela Franco, Johanna Viiliäinen, Mohiuddin Gazi, Oliver Frings, Erik Fredlund, Charles Spruck, Janne Lehtiö, Juha K Rantala, Lars-Gunnar Larsson, Olle Sangfelt
Publikováno v:
eLife, Vol 9 (2020)
Inhibition of WEE1 kinase by AZD1775 has shown promising results in clinical cancer trials, but markers predicting AZD1775 response are lacking. Here we analysed AZD1775 response in a panel of human breast cancer (BC) cell lines by global proteome/tr
Externí odkaz:
https://doaj.org/article/c498116f3f834b90a997e94962d531e9
Autor:
Giuseppe Balistreri, Johanna Viiliäinen, Mikko Turunen, Raquel Diaz, Lauri Lyly, Pirita Pekkonen, Juha Rantala, Krista Ojala, Grzegorz Sarek, Mari Teesalu, Oxana Denisova, Karita Peltonen, Ilkka Julkunen, Markku Varjosalo, Denis Kainov, Olli Kallioniemi, Marikki Laiho, Jussi Taipale, Sampsa Hautaniemi, Päivi M Ojala
Publikováno v:
PLoS Pathogens, Vol 12, Iss 2, p e1005424 (2016)
Kaposi's sarcoma herpesvirus (KSHV) causes Kaposi's sarcoma and certain lymphoproliferative malignancies. Latent infection is established in the majority of tumor cells, whereas lytic replication is reactivated in a small fraction of cells, which is
Externí odkaz:
https://doaj.org/article/207f588768644df382ad16ba122175cb
Autor:
Guillaume Suffert, Georg Malterer, Jean Hausser, Johanna Viiliäinen, Aurélie Fender, Maud Contrant, Tomi Ivacevic, Vladimir Benes, Frédéric Gros, Olivier Voinnet, Mihaela Zavolan, Päivi M Ojala, Juergen G Haas, Sébastien Pfeffer
Publikováno v:
PLoS Pathogens, Vol 7, Iss 12, p e1002405 (2011)
Kaposi's sarcoma herpesvirus (KSHV) encodes a cluster of twelve micro (mi)RNAs, which are abundantly expressed during both latent and lytic infection. Previous studies reported that KSHV is able to inhibit apoptosis during latent infection; we thus t
Externí odkaz:
https://doaj.org/article/3e1319a9b25b4d58809a8612eb7109b1
Autor:
Alena Malyukova, Mari Lahnalampi, Ton Falqués, Petri Pölönen, Mikko Sipola, Juha Mehtonen, Susanna Teppo, Johanna Viiliäinen, Olli Lohi, Anna Hagstroem-Andersson, Merja Heinäniemi, Olle Sangfelt
Publikováno v:
Blood. 140:11576-11576
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3c225a2e144b15bcc8647b9969c9607c
https://doi.org/10.1182/blood-2022-168684
https://doi.org/10.1182/blood-2022-168684
Autor:
Mohiuddin Gazi, Juha Rantala, Henrik J. Johansson, Olle Sangfelt, Oliver Frings, Aldwin Suryo Rahmanto, Andrä Brunner, Marcela Franco, Charles Spruck, Johanna Viiliäinen, Erik Fredlund, Lars-Gunnar Larsson, Janne Lehtiö
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c53c8e54a27f45db2b06f5179b530796
https://doi.org/10.7554/elife.57894.sa2
https://doi.org/10.7554/elife.57894.sa2
Autor:
Annu Söderholm, Johanna Viiliäinen, Tommi Nyrönen, Hanna Eskelinen, Daniela Roell, Pekka T. Lehtovuori, Aria Baniahmad
Publikováno v:
Journal of Chemical Information and Modeling. 48:1882-1890
We have identified and profiled a set of androgen receptor (AR) binding compounds representing two nonsteroidal scaffolds from a public chemical database supplied by Asinex with virtual screening procedure incorporating our recently published 3D QSAR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a75038fae2cc52e34d4363f17d4cfdb7
https://doi.org/10.1021/ci800149w
https://doi.org/10.1021/ci800149w
Autor:
Tero Aittokallio, R. C. Matos, Johanna Viiliäinen, Tine Ysenbaert, K. Dzeyk, Janne Tynell, Jakob Stenman, Ashwini S. Nagaraj, Bhagwan Yadav, Emmy W. Verschuren, Olli Vapalahti, Tuula A. Nyman, Denis E. Kainov, Oxana V. Denisova, Tiina Öhman, Henrik Paavilainen, Xavier Saelens, Veijo Hukkanen, Päivi M. Ojala, Laura Kakkola, Suvi Kuivanen, Lin Feng, Ilkka Julkunen
Publikováno v:
Cell Death & Disease
ABT-263 and its structural analogues ABT-199 and ABT-737 inhibit B-cell lymphoma 2 (Bcl-2), BCL2L1 long isoform (Bcl-xL) and BCL2L2 (Bcl-w) proteins and promote cancer cell death. Here, we show that at non-cytotoxic concentrations, these small molecu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dfc34e258cde0ad5932e387be7f35a7e
https://doi.org/10.1038/cddis.2013.267
https://doi.org/10.1038/cddis.2013.267