Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Johanna Tapper"'
Autor:
Tatiana V. Kudling, James H.A. Clubb, Dafne C.A. Quixabeira, Joao M. Santos, Riikka Havunen, Alexander Kononov, Camilla Heiniö, Victor Cervera-Carrascon, Santeri Pakola, Saru Basnet, Susanna Grönberg-Vähä-Koskela, Victor Arias, Ivan Gladwyn-Ng, Katri Aro, Leif Bäck, Jari Räsänen, Ilkka Ilonen, Kristian Borenius, Mikko Räsänen, Otto Hemminki, Antti Rannikko, Anna Kanerva, Johanna Tapper, Akseli Hemminki
Publikováno v:
OncoImmunology, Vol 11, Iss 1 (2022)
Cytokines have proven to be effective for cancer therapy, however whilst low-dose monotherapy with cytokines provides limited therapeutic benefit, high-dose treatment can lead to a number of adverse events. Interleukin 7 has shown promising results i
Externí odkaz:
https://doaj.org/article/96eb628e223841adb5827f8868946542
Autor:
Camilla Heiniö, James Clubb, Tatiana Kudling, Dafne Quixabeira, Victor Cervera-Carrascon, Riikka Havunen, Susanna Grönberg-Vähä-Koskela, João Manuel Santos, Johanna Tapper, Anna Kanerva, Akseli Hemminki
Publikováno v:
Diseases, Vol 10, Iss 3, p 52 (2022)
Ovarian cancer (OvCa) is one of the most common gynecological cancers and has the highest mortality in this category. Tumors are often detected late, and unfortunately over 70% of OvCa patients experience relapse after first-line treatments. OvCa has
Externí odkaz:
https://doaj.org/article/359da3b62b0346adb78630d92bd6a403
Autor:
Sanna Pikkusaari, Manuela Tumiati, Anni Virtanen, Jaana Oikkonen, Yilin Li, Fernando Perez-Villatoro, Taru Muranen, Matilda Salko, Kaisa Huhtinen, Anna Kanerva, Heidi Koskela, Johanna Tapper, Riitta Koivisto-Korander, Titta Joutsiniemi, Ulla-Maija Haltia, Heini Lassus, Sampsa Hautaniemi, Anniina Färkkilä, Johanna Hynninen, Sakari Hietanen, Olli Carpén, Liisa Kauppi
Publikováno v:
Clinical Cancer Research. :OF1-OF14
Purpose: Deficiency in homologous recombination (HR) repair of DNA damage is characteristic of many high-grade serous ovarian cancers (HGSC). It is imperative to identify patients with homologous recombination–deficient (HRD) tumors as they are mos
Autor:
Astrid Murumägi, Daniela Ungureanu, Suleiman Khan, Mariliina Arjama, Katja Välimäki, Aleksandr Ianevski, Philipp Ianevski, Rebecka Bergström, Alice Dini, Anna Kanerva, Riitta Koivisto-Korander, Johanna Tapper, Heini Lassus, Mikko Loukovaara, Andrus Mägi, Akira Hirasawa, Daisuke Aoki, Vilja Pietiäinen, Teijo Pellinen, Ralf Bützow, Tero Aittokallio, Olli Kallioniemi
Publikováno v:
British Journal of Cancer. 128:678-690
Funding Information: This study was supported by grants from the Academy of Finland (grants 278741, 313267, 326238, 333583, 313267, 326238, and 344698), Academy of Finland Centre of Excellence for Translational Cancer Biology (grant 271845), Cancer S
Autor:
Liisa Kauppi, Olli Carpén, Sakari Hietanen, Johanna Hynninen, Anniina Färkkilä, Sampsa Hautaniemi, Heini Lassus, Ulla-Maija Haltia, Titta Joutsiniemi, Riitta Koivisto-Korander, Johanna Tapper, Heidi Koskela, Anna Kanerva, Kaisa Huhtinen, Matilda Salko, Taru Muranen, Fernando Perez-Villatoro, Yilin Li, Jaana Oikkonen, Anni Virtanen, Manuela Tumiati, Sanna Pikkusaari
Comparison of different fHR score cut-off values.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9cf2368cec2030b2f5e654a9ea7cd9ca
https://doi.org/10.1158/1078-0432.22490492
https://doi.org/10.1158/1078-0432.22490492
Autor:
Liisa Kauppi, Olli Carpén, Sakari Hietanen, Johanna Hynninen, Anniina Färkkilä, Sampsa Hautaniemi, Heini Lassus, Ulla-Maija Haltia, Titta Joutsiniemi, Riitta Koivisto-Korander, Johanna Tapper, Heidi Koskela, Anna Kanerva, Kaisa Huhtinen, Matilda Salko, Taru Muranen, Fernando Perez-Villatoro, Yilin Li, Jaana Oikkonen, Anni Virtanen, Manuela Tumiati, Sanna Pikkusaari
Tumor percentages estimated from H&E images and comparison between HR, ovaHRDScar and Telli2016 status.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5165fb84f8b6675c836c0e78cbb3859a
https://doi.org/10.1158/1078-0432.22490483.v1
https://doi.org/10.1158/1078-0432.22490483.v1
Autor:
Liisa Kauppi, Olli Carpén, Sakari Hietanen, Johanna Hynninen, Anniina Färkkilä, Sampsa Hautaniemi, Heini Lassus, Ulla-Maija Haltia, Titta Joutsiniemi, Riitta Koivisto-Korander, Johanna Tapper, Heidi Koskela, Anna Kanerva, Kaisa Huhtinen, Matilda Salko, Taru Muranen, Fernando Perez-Villatoro, Yilin Li, Jaana Oikkonen, Anni Virtanen, Manuela Tumiati, Sanna Pikkusaari
Purpose:Deficiency in homologous recombination (HR) repair of DNA damage is characteristic of many high-grade serous ovarian cancers (HGSC). It is imperative to identify patients with homologous recombination–deficient (HRD) tumors as they are most
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::576b149b8d2a58ae9d5515d1e7fccb01
https://doi.org/10.1158/1078-0432.c.6533165
https://doi.org/10.1158/1078-0432.c.6533165
Autor:
Matilda Salko, Fernando Perez-Villatoro, Jehad Aldahdooh, Anastasiya Chernenko, Elina Pietilä, Ashwini S Nagaraj, Maija Vääriskoski, Heini Lassus, Mikko Loukovaara, Anna Kanerva, Riitta Koivisto-Korander, Johanna Tapper, Jing Tang, Anni Virtanen, Anniina Färkkilä, Ulla-Maija Haltia
Publikováno v:
Ovarian cancer.
Autor:
Sushmita Katuwal, Ulla-Maija Haltia, Johanna Tapper, Saara Bryk, Juha S. Tapanainen, Eero Pukkala
Publikováno v:
Gynecologic oncology. 163(3)
Objective: Adult-type ovarian granulosa cell tumors (AGCTs) are hormonally active neoplasms with limited epidemiological data available. We evaluated the effect of parity and postmenopausal hormone therapy (HT) use on the risk of AGCT in a population
Autor:
Alejandra Cervera, Hugo M. Horlings, Noora Andersson, Mikko Anttonen, Ralf Bützow, Anniina Färkkilä, Marjut Pihlajoki, Markku Heikinheimo, Olli Carpén, Leila Unkila-Kallio, Johanna Tapper, Ursula Turpeinen, Ulla-Maija Haltia, Lotta Mäkinen, David B. Wilson
Publikováno v:
Journal of the Endocrine Society
Adult-type granulosa cell tumors (AGCTs) are sex-cord derived neoplasms with a propensity for late relapse. Hormonal modulators have been used empirically in the treatment of recurrent AGCT, albeit with limited success. To provide a more rigorous fou