Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Johanna Sens"'
Autor:
Yvonne Baron, Johanna Sens, Lucas Lange, Larissa Nassauer, Denise Klatt, Dirk Hoffmann, Marc-Jens Kleppa, Philippe Vollmer Barbosa, Maximilian Keisker, Viviane Steinberg, Julia D. Suerth, Florian W.R. Vondran, Johann Meyer, Michael Morgan, Axel Schambach, Melanie Galla
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 27, Iss , Pp 810-823 (2022)
DNA-modifying technologies, such as the CRISPR-Cas9 system, are promising tools in the field of gene and cell therapies. However, high and prolonged expression of DNA-modifying enzymes may cause cytotoxic and genotoxic side effects and is therefore u
Externí odkaz:
https://doaj.org/article/7d3c9c912d7a421e93b440a7eebf070a
Autor:
Theresa Buchegger, Daniel Brand, Friederike Philipp, Christine S. Falk, Philippe Vollmer Barbosa, Doris Steinemann, Daniela Lenz, Dirk Hoffmann, Sebastian Brennig, Axel Schambach, Nico Lachmann, Johanna Sens, Michael A. Morgan, Christoph Klein, Johannes Kuehle
Publikováno v:
Journal of Personalized Medicine
Journal of Personalized Medicine, Vol 11, Iss 221, p 221 (2021)
Volume 11
Issue 3
Journal of Personalized Medicine, Vol 11, Iss 221, p 221 (2021)
Volume 11
Issue 3
Patient material from rare diseases such as very early-onset inflammatory bowel disease (VEO-IBD) is often limited. The use of patient-derived induced pluripotent stem cells (iPSCs) for disease modeling is a promising approach to investigate disease
Autor:
Franziska U. Huschmann, Janis Mueller, Alexander Metz, Moritz Ruf, Johanna Senst, Serghei Glinca, Johannes Schiebel, Andreas Heine, Gerhard Klebe
Publikováno v:
Crystals, Vol 14, Iss 9, p 755 (2024)
Fragment screening directly on protein crystals has been applied using AnalytiCon’s collection of intermediates that have been utilized to generate libraries of larger synthetic natural product-like molecules. The fragments with well-balanced physi
Externí odkaz:
https://doaj.org/article/4e95b53a82e24820bf05c4f364b32dbd
Autor:
Michael A. Morgan, Dirk Hoffmann, Lucas Lange, Johanna Sens, Christine S. Falk, Philippe Vollmer Barbosa, Axel Schambach
Publikováno v:
Human gene therapy. 32(1-2)
Samples from patients with rare diseases, such as primary immunodeficiencies, are often limited, which hampers careful analysis of the pathomechanisms involved in immune cell dysregulation. To overcome this issue, induced pluripotent stem cells (iPSC