Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Johanna Schleifenbaum"'
Autor:
Zhihuang Zheng, Dmitry Tsvetkov, Theda Ulrike Patricia Bartolomaeus, Cem Erdogan, Ute Krügel, Johanna Schleifenbaum, Michael Schaefer, Bernd Nürnberg, Xiaoning Chai, Friedrich-Alexander Ludwig, Gabriele N’diaye, May-Britt Köhler, Kaiyin Wu, Maik Gollasch, Lajos Markó
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-14 (2022)
Abstract Transient receptor potential channel subfamily C, member 6 (TRPC6), a non-selective cation channel that controls influx of Ca2+ and other monovalent cations into cells, is widely expressed in the kidney. TRPC6 gene variations have been linke
Externí odkaz:
https://doaj.org/article/eb5f803dda7d4cc3b54bebbbb62c7430
Autor:
Yingqiu Cui, Mario Kassmann, Sophie Nickel, Chenglin Zhang, Natalia Alenina, Yoland Marie Anistan, Johanna Schleifenbaum, Michael Bader, Donald G. Welsh, Yu Huang, Maik Gollasch
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 11, Iss 4 (2022)
Background Blood pressure and tissue perfusion are controlled in part by the level of intrinsic (myogenic) arterial tone. However, many of the molecular determinants of this response are unknown. We previously found that mice with targeted disruption
Externí odkaz:
https://doaj.org/article/2f2b387a1d25417a95ee41bf8a6174e8
Autor:
Steffen Cordes, Zeinab Mokhtari, Maria Bartosova, Sarah Mertlitz, Katarina Riesner, Yu Shi, Jörg Mengwasser, Martina Kalupa, Aleixandria McGeary, Johanna Schleifenbaum, Jens Schrezenmeier, Lars Bullinger, Maribel Diaz-Ricart, Marta Palomo, Enric Carrreras, Gernot Beutel, Claus Peter Schmitt, Andreas Beilhack, Olaf Penack
Publikováno v:
Haematologica, Vol 106, Iss 8 (2020)
Clinical studies suggested that endothelial dysfunction and damage could be involved in the development and severity of acute graft-versus-host disease (aGVHD). Accordingly, we found increased percentage of apoptotic Casp3+ blood vessels in duodenal
Externí odkaz:
https://doaj.org/article/66df618b08964e8ba01520caab1334a6
Autor:
Cheng Zhong, Johanna Schleifenbaum
Publikováno v:
Frontiers in Medicine, Vol 6 (2019)
Hypertension is ranked as the third cause of disability-adjusted life-years. The percentage of the population suffering from hypertension will continue to increase over the next years. Renovascular disease is one of the most common causes of secondar
Externí odkaz:
https://doaj.org/article/ad8072708ca24e1b93b358fdc5f364a3
Autor:
Johanna Schleifenbaum
Publikováno v:
Frontiers in Medicine, Vol 6 (2019)
Only a few years ago, alamandine was found to be a member of the protective arm of the renin-angiotensin system. It turned out to be an endogenous ligand of the G protein-coupled receptor MrgD. So far, MrgD had predominantly been studied in a neurona
Externí odkaz:
https://doaj.org/article/7272ab0655784bfbbc47f0820ce6fc9f
Autor:
Mario Kaßmann, István András Szijártó, Concha F. García‐Prieto, Gang Fan, Johanna Schleifenbaum, Yoland‐Marie Anistan, Christoph Tabeling, Yu Shi, Ferdinand le Noble, Martin Witzenrath, Yu Huang, Lajos Markó, Mark T. Nelson, Maik Gollasch
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 8, Iss 9 (2019)
Background Hypertension is the major risk factor for cardiovascular disease, the most common cause of death worldwide. Resistance arteries are capable of adapting their diameter independently in response to pressure and flow‐associated shear stress
Externí odkaz:
https://doaj.org/article/a9b9c6e3995a44efbfea4301b0b60f40
Autor:
Carolin Köhn, Johanna Schleifenbaum, István András Szijártó, Lajos Markó, Galyna Dubrovska, Yu Huang, Maik Gollasch
Publikováno v:
PLoS ONE, Vol 7, Iss 8, p e41951 (2012)
BACKGROUND: Hydrogen sulfide (H(2)S) is a potent vasodilator. However, the complex mechanisms of vasoregulation by H(2)S are not fully understood. We tested the hypotheses that (1) H(2)S exerts vasodilatory effects by opening KCNQ-type voltage-depend
Externí odkaz:
https://doaj.org/article/bfdf2eb03a97442f82739c4432f8b09f
Autor:
Pratik H. Khedkar, Falk-Bach Lichtenberger, Sengül Boral, Cheng Zhong, Maik Gollasch, Minze Xu, Pontus B. Persson, Holger Summer, Andreas Patzak, Cem Erdogan, Stefan Golz, Johanna Schleifenbaum
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 11412, p 11412 (2021)
International Journal of Molecular Sciences
Volume 22
Issue 21
International Journal of Molecular Sciences
Volume 22
Issue 21
Endothelial dysfunction (ED) comes with age, even without overt vessel damage such as that which occurs in atherosclerosis and diabetic vasculopathy. We hypothesized that aging would affect the downstream signalling of the endothelial nitric oxide (N
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::029754c71fd7f6003c73fbe2759b2708
https://www.mdpi.com/1422-0067/22/21/11412
https://www.mdpi.com/1422-0067/22/21/11412
Autor:
Zhihuang Zheng, Dmitry Tsvetkov, Theda Ulrike Patricia Bartolomaeus, Cem Erdogan, Ute Krügel, Johanna Schleifenbaum, Michael Schaefer, Bernd Nürnberg, Xiaoning Chai, Friedrich-Alexander Ludwig, Gabriele N’diaye, May-Britt Köhler, Kaiyin Wu, Maik Gollasch, Lajos Markó
Publikováno v:
Scientific Reports 12(2022), 3038
Transient receptor potential channel subfamily C, member 6 (TRPC6), a non-selective cation channel that controls influx of Ca2+ and other monovalent cations into cells, is widely expressed in the kidney. TRPC6 gene variations have been linked to chro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a47c1e7f4611b497061cce720d7a1b96
https://pubmed.ncbi.nlm.nih.gov/35194063
https://pubmed.ncbi.nlm.nih.gov/35194063
Autor:
Yingqiu Cui, Sophie Nickel, Johanna Schleifenbaum, Cheng-Lin Zhang, Donald G. Welsh, Maik Gollasch, Michael Bader, Yu Huang, Yoland Marie Anistan, Natalia Alenina, Mario Kassmann
BackgroundThe myogenic response is an inherent vasoconstrictive property of resistance arteries to keep blood flow constant in response to increases in intravascular pressure. Angiotensin II (Ang II) type 1 receptors (AT1R) are broadly distributed, m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::361cc4d2e47d43e9bba9c22fdd9f3514
https://doi.org/10.1101/2020.09.09.289280
https://doi.org/10.1101/2020.09.09.289280
