Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Johanna S. Ungerstedt"'
Autor:
Jennine Grootens, Johanna S. Ungerstedt, Maria Ekoff, Elin Rönnberg, Monika Klimkowska, Rose-Marie Amini, Michel Arock, Stina Söderlund, Mattias Mattsson, Gunnar Nilsson, Joakim S. Dahlin
Publikováno v:
EBioMedicine, Vol 43, Iss , Pp 150-158 (2019)
Background: Systemic mastocytosis (SM) is a haematological disease characterised by organ infiltration by neoplastic mast cells. Almost all SM patients have a mutation in the gene encoding the tyrosine kinase receptor KIT causing a D816V substitution
Externí odkaz:
https://doaj.org/article/44d2448fcd544af3a5923d8153cdc1da
Autor:
Chenyan Wu, Daryl Boey, Oscar Bril, Jennine Grootens, M. S. Vijayabaskar, Chiara Sorini, Maria Ekoff, Nicola K. Wilson, Johanna S. Ungerstedt, Gunnar Nilsson, Joakim S. Dahlin
Publikováno v:
Blood advances, 6(15), 4439-4449. American Society of Hematology
Mast cell accumulation is a hallmark of a number of diseases, including allergic asthma and systemic mastocytosis. Immunoglobulin E–mediated crosslinking of the FcεRI receptors causes mast cell activation and contributes to disease pathogenesis. T
Autor:
Monika Dolinska, Huan Cai, Alma Mansson, Jingyi Shen, Pingnan Xiao, Thibault Bouderlique, Xidan Li, Elory Leonard, Marcus Chang, Yuchen Gao, Juan Pablo Medina Giménez, Makoto Kondo, Lakshmi Sandhow, Anne-Sofie Johansson, Stefan Deneberg, Stina Söderlund, Martin Jädersten, Johanna S Ungerstedt, Magnus Tobiasson, Arne Östman, Satu Mustjoki, Leif Stenke, Katarina Le Blanc, Eva S Hellstrom-Lindberg, Sören Lehmann, Marja Ekblom, Ulla Olsson-Strömberg, Mikael Sigvardsson, Hong Qian
Publikováno v:
Blood.
Although tyrosine kinase inhibitors are effective for treating chronic myeloid leukemia (CML), they often fail to eradicate the leukemia-initiating stem cells (LSCs), causing disease persistence and relapse. Evidence indicates that LSC persistence ma