Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Johanna Reul"'
Autor:
Johanna Reul, Janina Frisch, Christine E. Engeland, Frederic B. Thalheimer, Jessica Hartmann, Guy Ungerechts, Christian J. Buchholz
Publikováno v:
Frontiers in Oncology, Vol 9 (2019)
Immune checkpoint inhibitors (ICIs) can block distinct receptors on T cells or tumor cells thus preventing T cell inactivation and tumor immune escape. While the clinical response to treatment with ICIs in cancer patients is impressive, this therapy
Externí odkaz:
https://doaj.org/article/c9b2651adab048cc8ecea4b5e41846c3
Autor:
Alexander Muik, Hanauer Jds, Thorsten Friedel, Johanna Reul, Sebastian Newrzela, Pfeiffer A, Christian J. Buchholz, Irene C. Schneider, M. L. Hansmann, Dina Kleinlützum, Benjamin Rengstl
Publikováno v:
Oncotarget
Classical Hodgkin lymphoma (cHL) is a hematopoietic malignancy with a characteristic cellular composition. The tumor mass is made up of infiltrated lymphocytes and other cells of hematologic origin but only very few neoplastic cells that are mainly i
Autor:
Irene C. Schneider, Alexander Muik, Anke Muth, Christian J. Buchholz, Robert C. Münch, Karen Patricia Hartmann, Johanna Reul, Thorsten Friedel
Publikováno v:
Biomaterials. 144:84-94
We have established a novel approach for the covalent coupling of large polypeptides to the surface of fully assembled adeno-associated viral gene transfer vector (AAV) particles via split-intein mediated protein-trans-splicing (PTS). This way, we ac
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1950
Cell entry of AAV vectors is initiated by contacting the cell surface attachment receptor. This process can be rationally engineered through mutating the contact residues on the AAV capsid and covalently coupling targeting ligands to the capsid surfa
Publikováno v:
Methods in Molecular Biology ISBN: 9781493991389
Cell entry of AAV vectors is initiated by contacting the cell surface attachment receptor. This process can be rationally engineered through mutating the contact residues on the AAV capsid and covalently coupling targeting ligands to the capsid surfa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8aad2305150b51f6c499cd51c1f48d33
https://doi.org/10.1007/978-1-4939-9139-6_3
https://doi.org/10.1007/978-1-4939-9139-6_3
Publikováno v:
Molecular Therapy. 24:S78
Immunotherapy has been shown to be an effective treatment modality for various cancer types. A branch of immunotherapy is oncolytic immunovirotherapy, which relies on arming oncolytic viruses with immunomodulatory cargo. A potent oncolytic virus cand