Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Johanna Raiman"'
Publikováno v:
International Journal of Pharmaceutics. 261:129-136
The major disadvantage concerning clinical use of bishosphonate drugs, like clodronate, is their poor and variable absorption after oral administration. The objective of this study was to assess the effects of four different absorption enhancers—pa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e9a18de454b6acb886798516b61474f
https://doi.org/10.1016/s0378-5173(03)00300-4
https://doi.org/10.1016/s0378-5173(03)00300-4
Autor:
Johanna Raiman, Jouni Hirvonen, Jozef Cizmarik, Lenka Gyürösiova, Leena Laitinen, Eva Sedlárová
Publikováno v:
Pharmaceutical Research. 19:162-168
Purpose. The purpose of the present research was to study 10 m-alkoxysubstituted pyrrolidinoethylesters of phenylcarbamic acid—potential local anesthetics. The relationships between the structure of the molecule, its physicochemical parameters (log
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2a0122c13232213a027e7188e47656b4
https://doi.org/10.1023/a:1014208515545
https://doi.org/10.1023/a:1014208515545
Publikováno v:
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences. 21(2-3)
Poor absorption and stability of peptides are the major obstacles concerning the development of therapeutically relevant iontophoretic devices for the transdermal delivery of peptides. The present study examined the impact of constant and pulsed (dir
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e1d8575f803722e2b6113e60eab543e
https://pubmed.ncbi.nlm.nih.gov/14757511
https://pubmed.ncbi.nlm.nih.gov/14757511
Autor:
Lenka, Gyürösiová, Leena, Laitinen, Johanna, Raiman, Jozef, Cizmárik, Eva, Sedlárová, Jouni, Hirvonen
Publikováno v:
Pharmaceutical research. 19(2)
The purpose of the present research was to study 10 m-alkoxysubstituted pyrrolidinoethylesters of phenylcarbamic acid-potential local anesthetics. The relationships between the structure of the molecule, its physicochemical parameters (log D(oct), lo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e822e39b98232c4f82ec6a3745dfa82e
https://pubmed.ncbi.nlm.nih.gov/11883643
https://pubmed.ncbi.nlm.nih.gov/11883643
Publikováno v:
International journal of pharmaceutics. 213(1-2)
Clodronate, like other bisphosphonates, is poorly absorbed from the gastrointestinal tract, mainly due to its high hydrophilicity and ability to form complexes with divalent cations in the gastrointestinal tract. One strategy for improving oral absor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d6907a955160298e084b2c69d098b60
https://pubmed.ncbi.nlm.nih.gov/11165101
https://pubmed.ncbi.nlm.nih.gov/11165101
Publikováno v:
Aalto University
The objective of this study was to investigate the drug adsorption process in human skin using in vitro streaming potential measurements. Streaming potential is an electrokinetic phenomenon, which reflects both the charge density and the pore size of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d8926ec9c8c00ac128d2593c8c8ee6b
https://research.aalto.fi/en/publications/a3ba0553-2485-4efe-b3e3-780c668e995f
https://research.aalto.fi/en/publications/a3ba0553-2485-4efe-b3e3-780c668e995f
