Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Johanna R. Möller"'
Publikováno v:
Neurochemical Research. 23:1005-1010
Purified human central nervous system myelin contains an endogenous cysteine protease which degrades the 100-kDa myelin-associated glycoprotein into a slightly smaller 90-kDa derivative called dMAG, and which has been implicated in demyelinating dise
Publikováno v:
Journal of Neurochemistry. 58:1829-1835
An autoantibody occurring in the serum of an apparently normal rabbit that immunocytochemically stains myelin sheaths and oligodendrocytes in rat brain was shown to react specifically with the 46-kDa isoform of 2′,3′-cyclic nucleotide 3′-phosph
Publikováno v:
Biochemistry. 36(8)
Myelin-associated glycoprotein (MAG) is a transmembrane structural protein that is thought to be involved in the formation and/or maintenance of the myelin sheath. MAG is proteolyzed at a discrete location near its transmembrane domain by a calcium a
Autor:
Johanna R. Möller
Publikováno v:
Brain research. 741(1-2)
Myelin-associated glycoprotein (MAG) is susceptible to proteolysis by a calcium-activated neutral protease which is located in myelin. The conversion of MAG (M(r) 100,000) to its soluble derivative dMAG (M(r) 90,000) occurs much more rapidly in myeli
Publikováno v:
Brain research. Developmental brain research. 91(1)
Caprine β-mannosidosis is an inherited lysosomal storage disease that leads to a deficiency of oligodendrocytes and hypomyelination. Our previous results demonstrated that low levels of myelin-associated glycoprotein (MAG), 2′,3′-cyclic nucleoti
Autor:
Johanna R. Möller, Raphael Schiffmann, Roscoe O. Brady, Jeffry R. Alger, Peter E. Hauer, John D. Heiss, Richard H. Quarles, Bruce D. Trapp, Christine R. Kaneski, David A. Katz, Henry H L Shih, Colette C. Parker, Edward M. Kaye, Robert G. Farrer, Norman W. Barton
Publikováno v:
Annals of neurology. 35(3)
A significant number of patients with progressive leukodystrophy do not have a definitive diagnosis. This report describes the clinical, morphological, and biochemical characteristics of 4 unrelated girls with progressive ataxic diplegia of unknown e
Autor:
Richard H. Quarles, David Johnson, Wallace W. Tourtellotte, Johanna R. Möller, Roscoe O. Brady
Publikováno v:
Journal of neuroimmunology. 22(1)
Cerebrospinal fluids (CSF) and sera from patients with multiple sclerosis (MS), other neurological diseases (ONDs) and healthy controls were tested for antibodies to myelin-associated glycoprotein (MAG) by several different assays. Using a very sensi