Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Johanna P. Laakkonen"'
Autor:
Galina Wirth, Greta Juusola, Santeri Tarvainen, Johanna P. Laakkonen, Petra Korpisalo, Seppo Ylä-Herttuala
Publikováno v:
Cells, Vol 12, Iss 16, p 2060 (2023)
This study aimed to show the significance of capillary function in post-ischemic recovery from the perspective of physiological parameters, such as blood flow, hemoglobin oxygenation and tissue regeneration. Muscle-level microvascular alterations of
Externí odkaz:
https://doaj.org/article/9df7c71d7d754e2eb2cc4eeadf523c8b
Autor:
Miika Kiema, Jaakko K. Sarin, S. Petteri Kauhanen, Jari Torniainen, Hanna Matikka, Emma-Sofia Luoto, Pekka Jaakkola, Petri Saari, Timo Liimatainen, Ritva Vanninen, Seppo Ylä-Herttuala, Marja Hedman, Johanna P. Laakkonen
Publikováno v:
Frontiers in Physiology, Vol 13 (2022)
Objectives: In thoracic aortic aneurysm (TAA) of the ascending aorta (AA), AA is progressively dilating due to the weakening of the aortic wall. Predicting and preventing aortic dissections and ruptures in TAA continues to be challenging, and more ac
Externí odkaz:
https://doaj.org/article/67a2d2a3fb9e4a65adf1b54ea2b12844
Autor:
Pyry I. Toivanen, Tiina Nieminen, Johanna P. Laakkonen, Tommi Heikura, Minna U. Kaikkonen, Seppo Ylä-Herttuala
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-12 (2017)
Abstract Vascular Endothelial Growth Factors (VEGFs) are promising molecules for the treatment of ischemic diseases by pro-angiogenic therapy. Snake venom VEGFs are a novel subgroup with unique receptor binding profiles and as such are potential new
Externí odkaz:
https://doaj.org/article/027dea479a8e4616b514504c345ea716
Autor:
Suvi Jauhiainen, Johanna P. Laakkonen, Kirsi Ketola, Pyry I. Toivanen, Tiina Nieminen, Takeshi Ninchoji, Anna-Liisa Levonen, Minna U. Kaikkonen, Seppo Ylä-Herttuala
Publikováno v:
Frontiers in Physiology, Vol 10 (2019)
Vascular endothelial growth factors (VEGFs) are key mediators of endothelial cell (EC) function in angiogenesis. Emerging knowledge also supports the involvement of axon guidance-related factors in the regulation of angiogenesis and vascular patterni
Externí odkaz:
https://doaj.org/article/f2c61d3554834120acd95abb744ff1d3
Autor:
Annakaisa Tirronen, Nicholas L. Downes, Jenni Huusko, Johanna P. Laakkonen, Tomi Tuomainen, Pasi Tavi, Marja Hedman, Seppo Ylä-Herttuala
Publikováno v:
Biomolecules, Vol 11, Iss 3, p 452 (2021)
Molecular mechanisms involved in cardiac remodelling are not fully understood. To study the role of vascular endothelial growth factor receptor 1 (VEGFR-1) signaling in left ventricular hypertrophy (LVH) and heart failure, we used a mouse model lacki
Externí odkaz:
https://doaj.org/article/93b4a1806b00496a9c09ef69d9585269
Autor:
Jaakko K. Sarin, Miika Kiema, Emma-Sofia Luoto, Annastiina Husso, Marja Hedman, Johanna P. Laakkonen, Jari Torniainen
Publikováno v:
Journal of Surgical Research. 287:82-89
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a46792b417563215cbf1143de0e3ff70
https://doi.org/10.1016/j.jss.2023.01.016
https://doi.org/10.1016/j.jss.2023.01.016
Autor:
Suvi Jauhiainen, Henna Ilmonen, Pia Vuola, Heta Rasinkangas, Heidi H Pulkkinen, Sara Keränen, Miika Kiema, Jade J Liikkanen, Nihay Laham Karam, Svetlana Laidinen, Mustafa Beter, Einari Aavik, Kimmo Lappalainen, Jouko Lohi, Johanna Aronniemi, Tiit Örd, Minna U Kaikkonen, Päivi Salminen, Erkki Tukiainen, Seppo Ylä-Herttuala, Johanna P Laakkonen
Publikováno v:
eLife. 12
Background: Sporadic venous malformation (VM) and angiomatosis of soft tissue (AST) are benign, congenital vascular anomalies affecting venous vasculature. Depending on the size and location of the lesion, symptoms vary from motility disturbances to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::89e0a26c859af2984f2a6760b3bd5a9a
https://doi.org/10.7554/elife.82543
https://doi.org/10.7554/elife.82543
Autor:
Henna Ilmonen, Suvi Jauhiainen, Pia Vuola, Heta Rasinkangas, Heidi H Pulkkinen, Sara Keränen, Miika Kiema, Jade J Liikkanen, Nihay Laham-Karam, Svetlana Laidinen, Einari Aavik, Kimmo Lappalainen, Jouko Lohi, Johanna Aronniemi, Tiit Örd, Minna U Kaikkonen, Päivi Salminen, Erkki Tukiainen, Seppo Ylä-Herttuala, Johanna P Laakkonen
Background: Sporadic venous malformation (VM) and angiomatosis of soft tissue (AST) are benign, congenital vascular anomalies affecting venous vasculature. Depending on the size and location of the lesion, symptoms vary from motility disturbances to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f8e21851ccfb661ac4de30e1d06d7dfc
https://doi.org/10.1101/2022.09.23.509204
https://doi.org/10.1101/2022.09.23.509204
Autor:
Sara Keränen, Doug Marchuk, Santeri Suutarinen, Timo Krings, Diana E. Guo, Juhana Frösen, Michael T. Lawton, Rahul Mallick, Johanna P. Laakkonen, Marie E. Faughnan, Seppo Ylä-Herttuala, Behnam Rezai Jahromi, Ivan Radovanovic, Timo Koivisto, Helen Kim, Ludmila Pawlikowska, Tuomas Rauramaa
Publikováno v:
Acta neurochirurgica, vol 163, iss 9
Acta Neurochirurgica
Acta Neurochirurgica
Background Brain arteriovenous malformations (bAVM) may rupture causing disability or death. BAVM vessels are characterized by abnormally high flow that in general triggers expansive vessel remodeling mediated by cyclo-oxygenase-2 (COX2), the target
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50cd6fe5223b6ee380b70f10fa2365e1
https://doi.org/10.1007/s00701-021-04895-z
https://doi.org/10.1007/s00701-021-04895-z
Autor:
Pierre Moreau, Vanesa Tomas Bosch, Maria Bouvy-Liivrand, Kadri Õunap, Minna U. Kaikkonen, Suvi Linna-Kuosmanen, Johanna P. Laakkonen, Tiit Örd, Heidi H. Pulkkinen, Merja Heinäniemi, Seppo Ylä-Herttuala, Petri Pölönen
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology
Supplemental Digital Content is available in the text.
Objective: Atherosclerosis is the underlying cause of most cardiovascular diseases. The main cell types associated with disease progression in the vascular wall are endothelial cells, smooth
Objective: Atherosclerosis is the underlying cause of most cardiovascular diseases. The main cell types associated with disease progression in the vascular wall are endothelial cells, smooth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d955376147581f99cba65228dec450f
http://europepmc.org/articles/PMC8216629
http://europepmc.org/articles/PMC8216629