Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Johanna Meier-Soelch"'
Autor:
Jasmin Priester, Johanna Meier-Soelch, Hendrik Weiser, Daniel Heylmann, Axel Weber, Uwe Linne, Michael Kracht
Publikováno v:
STAR Protocols, Vol 4, Iss 2, Pp 102195- (2023)
Summary: The unbiased identification of cytokine-induced, secreted proteins from cells cultured in serum-containing medium is challenging. Here, we describe an experimental and bioinformatics workflow to label interleukin-1α-regulated proteins in li
Externí odkaz:
https://doaj.org/article/6971a1607610402ca927b0d82aaf7e32
Autor:
Mohammed Samer Shaban, Christin Müller, Christin Mayr-Buro, Hendrik Weiser, Johanna Meier-Soelch, Benadict Vincent Albert, Axel Weber, Uwe Linne, Torsten Hain, Ilya Babayev, Nadja Karl, Nina Hofmann, Stephan Becker, Susanne Herold, M. Lienhard Schmitz, John Ziebuhr, Michael Kracht
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-20 (2021)
Here, Shaban et al. show that coronaviruses modulate ER stress and the unfolded protein response. The ER stress inducer thapsigargin exerts potent antiviral effects, partially reverses the virus-induced translational shut-down, reprograms the host pr
Externí odkaz:
https://doaj.org/article/a6f9af13b42d437eab2e9eaf4c3fe912
Publikováno v:
Cells, Vol 10, Iss 4, p 753 (2021)
Activation of the transcription factor NF-κB elicits an individually tailored transcriptional response in order to meet the particular requirements of specific cell types, tissues, or organs. Control of the induction kinetics, amplitude, and termina
Externí odkaz:
https://doaj.org/article/f7cb7b2b262c43f98aaf6346cbd35f6a
Autor:
Johanna Meier-Soelch, Liane Jurida, Axel Weber, Doris Newel, Johnny Kim, Thomas Braun, M. Lienhard Schmitz, Michael Kracht
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
The potent proinflammatory cytokine interleukin (IL)-1 triggers gene expression through the NF-κB signaling pathway. Here, we investigated the cofactor requirements of strongly regulated IL-1 target genes whose expression is impaired in p65 NF-κB-d
Externí odkaz:
https://doaj.org/article/1f677be71ca24920936cc7de11e4258b
Autor:
Mohammed Samer Shaban, Christin Mayr-Buro, Johanna Meier-Soelch, Benadict Vincent Albert, M. Lienhard Schmitz, John Ziebuhr, Michael Kracht
Publikováno v:
Trends in Pharmacological Sciences. 43:557-568
Despite the great success of vaccines that protect against RNA virus infections, and the development and clinical use of a limited number of RNA virus-specific drugs, there is still an urgent need for new classes of antiviral drugs against circulatin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6644f5e8c034bc14e582181c551b9220
https://doi.org/10.1016/j.tips.2022.04.004
https://doi.org/10.1016/j.tips.2022.04.004
Autor:
Tilman Borggrefe, Marek Bartkuhn, Thorsten Stiewe, Patricia Klöble, Daniel Mertens, Francesca Ferrante, Andrea Nist, Steffen Just, Viola Close, Johanna Meier-Soelch, Benedetto Daniele Giaimo, Franz Oswald, Michael Kracht, Tobias Zimmermann
Publikováno v:
Nucleic Acids Research
Aberrant Notch signaling plays a pivotal role in T-cell acute lymphoblastic leukemia (T-ALL) and chronic lymphocytic leukemia (CLL). Amplitude and duration of the Notch response is controlled by ubiquitin-dependent proteasomal degradation of the Notc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::057d336560bd7dff5889b69f6093f682
http://europepmc.org/articles/PMC7144913
http://europepmc.org/articles/PMC7144913
Autor:
Thorsten Stiewe, Michael Kracht, Robert Liefke, Tabea Riedlinger, Andrea Nist, Johanna Meier-Soelch, Liane Jurida, M. Lienhard Schmitz
Publikováno v:
The FASEB Journal
Increasing evidence shows that many transcription factors execute important biologic functions independent from their DNA-binding capacity. The NF-κB p65 (RELA) subunit is a central regulator of innate immunity. Here, we investigated the relative fu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e674dc7e6c08a23ceaca9369056ce4aa
https://doi.org/10.1096/fj.201801638r
https://doi.org/10.1096/fj.201801638r
Autor:
Michael Kracht, Knut Beuerlein, Oliver Dittrich-Breiholz, Lilija Brant, Thorsten Stiewe, Helmut Müller, Theodore Georgomanolis, Axel Weber, Tabea Riedlinger, M. Lienhard Schmitz, Wilfred F. J. van IJcken, Argyris Papantonis, Sinah-Sophia Weiterer, Marek Bartkuhn, Ulas Tenekeci, Christin Mayr-Buro, Anna Beyerlein, Hendrik Weiser, Liane Jurida, Johanna Meier-Soelch, Andrea Nist, Athanasia Mizi
Publikováno v:
The EMBO Journal
EMBO Journal, 39(1):e101533. Wiley-Blackwell
EMBO Journal, 39(1):e101533. Wiley-Blackwell
How cytokine‐driven changes in chromatin topology are converted into gene regulatory circuits during inflammation still remains unclear. Here, we show that interleukin (IL)‐1α induces acute and widespread changes in chromatin accessibility via t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c0c41122d0cb206c6294c3429b1372b
http://europepmc.org/articles/PMC6939198
http://europepmc.org/articles/PMC6939198
Autor:
Johanna Meier-Soelch, Michael Kracht, M. Lienhard Schmitz, Knut Beuerlein, Ulas Tenekeci, Eva Schlereth, Christin Mayr-Buro
Publikováno v:
Cancers
Cancers, Vol 11, Iss 8, p 1199 (2019)
Volume 11
Issue 8
Cancers, Vol 11, Iss 8, p 1199 (2019)
Volume 11
Issue 8
The frequently occurring heterogeneity of cancer cells and their functional interaction with immune cells in the tumor microenvironment raises the need to study signaling pathways at the single cell level with high precision, sensitivity, and spatial
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6e722ffee0942fc679349e819f279e0
https://pubmed.ncbi.nlm.nih.gov/31426445
https://pubmed.ncbi.nlm.nih.gov/31426445