Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Johanna M. Mäkinen"'
Autor:
Vesa-Matti Pohjanen, Olli-Pekka Koivurova, Heikki Huhta, Olli Helminen, Johanna M Mäkinen, Jari M Karhukorpi, Tapio Joensuu, Pentti O Koistinen, Jarno M Valtonen, Seppo E Niemelä, Riitta A Karttunen, Tuomo J Karttunen
Publikováno v:
PLoS ONE, Vol 10, Iss 7, p e0131553 (2015)
Toll-like receptor 4 is a part of the innate immune system and recognizes Helicobacter pylori lipopolysaccharide. The goal of this study was to analyze the role of Toll-like receptor 4 polymorphisms +896 (rs4986790) and +1196 (rs4986791) in the patho
Externí odkaz:
https://doaj.org/article/99b49961b7934b0fa17d5fdf8e4eaa9c
Autor:
Johanna M. Mäkinen, Riitta Mäkitaro, Riitta Kaarteenaho, Shirley Johnson, Kirsi Laitakari, Paavo Pääkkö, Risto Bloigu, Elisa Lappi-Blanco
Publikováno v:
Histopathology. 71(3)
Aims Until the launch of the International Association for the Study of Lung Cancer/American Thoracic Society/European Respiratory Society (IASLC/ATS/ERS) adenocarcinoma classification in 2011, there were no uniform histological grading criteria for
Autor:
Tuomo J. Karttunen, Jari Karhukorpi, Pentti O. Koistinen, Vesa-Matti Pohjanen, Jarno M. Valtonen, Riitta Karttunen, Seppo Niemelä, Tapio Joensuu, Johanna M. Mäkinen, Olli-Pekka Koivurova
Publikováno v:
Genes, Chromosomes and Cancer. 52:976-982
The aim of this study was to assess the significance of the interleukin 6 gene polymorphism -174 in gastric cancer risk. The interleukin 6 -174 G/C (rs1800795) gene polymorphisms was analyzed in gastric cancer, peptic ulcer, and nonulcer dyspepsia pa
Autor:
Johanna M. Mäkinen, Elisa Lappi-Blanco, Raija Sormunen, Siri Lehtonen, Risto Bloigu, Riitta Mäkitaro, Shirley Johnson, Kirsi Laitakari, Henna Karvonen, Riitta Kaarteenaho
Publikováno v:
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine. 37(10)
Mucin-1 (MUC1) affects cancer progression in lung adenocarcinoma, and its aberrant expression pattern has been correlated with poor tumor differentiation and impaired prognosis. In this study, the immunohistochemical expression of MUC1 and Mucin-4 (M
Autor:
Elisa Lappi-Blanco, Risto Bloigu, Siri Lehtonen, Timo Väisänen, Shirley Johnson, Johanna M. Mäkinen, Riitta Kaarteenaho, Kirsi Laitakari, Riitta Mäkitaro
Publikováno v:
11.1 Lung Cancer.
The depolarized expression of Mucin-1 (MUC1) is a marker of poor prognosis in lung cancer. MUC1 binds with the epithelial growth factor receptor 1 (EGFR), which is considered as a predictive marker in lung cancer, whereas the prognostic significance
Autor:
Riitta Mäkitaro, Riitta Kaarteenaho, Risto Bloigu, Shirley Johnson, Elisa Lappi-Blanco, Kirsi Laitakari, Johanna M. Mäkinen
Publikováno v:
Lung cancer (Amsterdam, Netherlands). 90(3)
Objectives Histologic heterogeneity is a typical feature of pulmonary adenocarcinoma. This study aimed to deconstruct the intratumoral growth pattern composition and to examine the prognostic relevance of the current lung adenocarcinoma classificatio
Autor:
Johanna M. Mäkinen, Juha B. Näpänkangas, Tuomo J. Karttunen, Kai Klintrup, Markus J. Mäkinen, Jyrki Mäkelä, Tuomo T. Hörkkö, Hannu Tuominen
Publikováno v:
European Journal of Cancer. 42:964-971
Cancer cell budding at the invasive margin has been associated with poor prognosis in rectal cancer. beta-Catenin is an adhesion protein involved in the nuclear Wnt/beta-catenin pathway, and mesenchymal transition of colorectal cancer cells. Hence, w
Publikováno v:
Journal of Histochemistry & Cytochemistry. 52:693-699
Fas (CD95, APO-1) is widely expressed on lymphatic cells, and by interacting with its natural ligand (Fas-L), Fas induces apoptosis through a complex caspase cascade. In this study we sought to survey Fas-L expression in vascular and sinusoidal struc
Autor:
Siri Lehtonen, Henna Karvonen, Elisa Lappi-Blanco, Shirley Johnson, Kirsi Laitakari, Terttu Harju, Raija Sormunen, Johanna M. Mäkinen, Riitta Kaarteenaho
Publikováno v:
Respiratory Research
Background Chronic obstructive pulmonary disease (COPD) is characterized by structural changes in alveoli and airways. Our aim was to analyse the numbers of alpha-smooth muscle actin (α-SMA) positive cells, as a marker of myofibroblasts, in differen
Autor:
Vesa-Matti, Pohjanen, Olli-Pekka, Koivurova, Johanna M, Mäkinen, Jari M, Karhukorpi, Tapio, Joensuu, Pentti O, Koistinen, Jarno M, Valtonen, Seppo E, Niemelä, Riitta A, Karttunen, Tuomo J, Karttunen
Publikováno v:
Genes, chromosomescancer. 52(10)
The aim of this study was to assess the significance of the interleukin 6 gene polymorphism -174 in gastric cancer risk. The interleukin 6 -174 G/C (rs1800795) gene polymorphisms was analyzed in gastric cancer, peptic ulcer, and nonulcer dyspepsia pa