Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Johanna M. Avis"'
Autor:
Natalie L. Stephenson, Johanna M. Avis
Publikováno v:
FEBS Open Bio, Vol 5, Iss 1, Pp 625-633 (2015)
The Notch signalling pathway is fundamental to cell differentiation in developing and self‐renewing tissues. Notch is activated upon ligand‐induced conformational change of the Notch negative regulatory region (NRR), unmasking a key proteolytic s
Externí odkaz:
https://doaj.org/article/bbe65295cefc4552a0ebedf9141e41eb
Autor:
Hideyuki Shimizu, Alexandre Djiane, Martin D. Jennings, Sarah J. Bray, Marian B. Wilkin, Sabine Mazleyrat, Martin Baron, Johanna M. Avis
Publikováno v:
The Journal of Cell Biology
Polychaetoid coordinates receptor trafficking and signaling with adherens junction organization.
Zona occludens (ZO) proteins are molecular scaffolds localized to cell junctions, which regulate epithelial integrity in mammals. Using newly genera
Zona occludens (ZO) proteins are molecular scaffolds localized to cell junctions, which regulate epithelial integrity in mammals. Using newly genera
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7169fe21fecbe328d973538e80b8f364
http://europepmc.org/articles/PMC3019562
http://europepmc.org/articles/PMC3019562
Autor:
Panagiotis Karahalios, Tanya V. Aspinall, James M B Gordon, John Paul Bukowski, Johanna M. Avis, Hayley J. Bennett, Scott C. Walker, David R. Engelke
Publikováno v:
Nucleic Acids Research
Ribonuclease MRP is an endonuclease, related to RNase P, which functions in eukaryotic pre-rRNA processing. In Saccharomyces cerevisiae, RNase MRP comprises an RNA subunit and ten proteins. To improve our understanding of subunit roles and enzyme arc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25f4288ccb6b8c3ad4c3838f17563650
http://europepmc.org/articles/PMC2095792
http://europepmc.org/articles/PMC2095792
Autor:
Martin Baron, Johanna M. Avis, Richard T. Blankley, Alexander P. Golovanov, Martin D. Jennings
Publikováno v:
Journal of Biological Chemistry. 282:29032-29042
WW domains target proline-tyrosine (PY) motifs and frequently function as tandem pairs. When studied in isolation, single WW domains are notably promiscuous and regulatory mechanisms are undoubtedly required to ensure selective interactions. Here, we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f46c5b0013f2f2f31bda8ed1269e5e41
https://doi.org/10.1074/jbc.m703453200
https://doi.org/10.1074/jbc.m703453200
Publikováno v:
Biochemistry. 41:5383-5396
A key ion-dependent folding unit within the hepatitis C IRES comprises the IIIef junction and pseudoknot. This region is also important in recruitment of the 40S ribosomal subunit. Here, circular dichroism is used to study the influence of metal ions
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4896e6c27d520e886d23b459a7d012c
https://doi.org/10.1021/bi0156310
https://doi.org/10.1021/bi0156310
Autor:
Veronica A. Raker, Johanna M. Avis, Reinhard Lührmann, C. Kambach, Robert I. M. Young, Kiyoshi Nagai, Jade Li, Eric de La Fortelle, S. Walke
Publikováno v:
Cell. 96(3):375-387
The U1, U2, U4/U6, and U5 small nuclear ribonucleoprotein particles (snRNPs) involved in pre-mRNA splicing contain seven Sm proteins (B/B′, D1, D2, D3, E, F, and G) in common, which assemble around the Sm site present in four of the major spliceoso
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3623ae62f2a42c2b23e56a735448544
Autor:
Johanna M. Avis, Paul Clarke
Publikováno v:
Journal of Cell Science. 109:2423-2427
Ran is a small GTPase that has been implicated in a variety of nuclear processes, including the maintainance of nuclear structure, protein import, mRNA processing and export, and cell cycle regulation. There has been significant progress in determini
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3fc5c4d246c00d478518e957ceebbf83
https://doi.org/10.1242/jcs.109.10.2423
https://doi.org/10.1242/jcs.109.10.2423
Publikováno v:
Trends in Biochemical Sciences. 20:235-240
The RNP domain is found in a number of proteins involved in processing and transport of mRNA precursors. The crystal structure of a complex between the U1A spliceosomal protein and its cognate RNA hairpin at 1.92 A resolution reveals the molecular ba
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28352c2ca114b56f83d748d386410ae2
https://doi.org/10.1016/s0968-0004(00)89024-6
https://doi.org/10.1016/s0968-0004(00)89024-6
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 941
The use of in vitro transcribed RNA is often limited by sequence constraints at the 5'-end and the problem of transcript heterogeneity which can occur at both the 5'- and 3'-ends. This chapter describes the use of cis-acting ribozymes, 5'-end hammerh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6d1e89935869580e2e13d24baad22d57
https://pubmed.ncbi.nlm.nih.gov/23065555
https://pubmed.ncbi.nlm.nih.gov/23065555
Autor:
Johanna M. Avis, Natalie L. Stephenson
The conserved Notch signaling pathway plays crucial roles in developing and self-renewing tissues. Notch is activated upon ligand-induced conformation change of the Notch negative regulatory region (NRR) unmasking a key proteolytic site (S2) and faci
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2a82b9528a61786b7b907c2e30b471a
https://europepmc.org/articles/PMC3478610/
https://europepmc.org/articles/PMC3478610/
