Výsledky vyhledávání - "Johanna M Eberhard"

Akademický článek

Comparison of the integrin α4β7 expression pattern of memory T cell subsets in HIV infection and ulcerative colitis.

Autor: Melanie Wittner, Veronika Schlicker, Jana Libera, Jan-Hendrik Bockmann, Thomas Horvatits, Oliver Seiz, Silke Kummer, Carolin F Manthey, Anja Hüfner, Marcus Kantowski, Thomas Rösch, Olaf Degen, Samuel Huber, Johanna M Eberhard, Julian Schulze Zur Wiesch

Publikováno v: PLoS ONE, Vol 14, Iss 7, p e0220008 (2019)

Anti-α4β7 therapy with vedolizumab (VDZ) has been suggested as possible immune intervention in HIV. Relatively little is known about the α4β7-integrin (α4β7) expression of different T-cell subsets in different anatomical compartments of healthy

Externí odkaz: https://doaj.org/article/da46818e3ce244f18c2b1b6134aefd36

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Akademický článek

Loss of CCR7 expression on CD56(bright) NK cells is associated with a CD56(dim)CD16⁺ NK cell-like phenotype and correlates with HIV viral load.

Autor: Henoch S Hong, Fareed Ahmad, Johanna M Eberhard, Nupur Bhatnagar, Benjamin A Bollmann, Phillip Keudel, Matthias Ballmaier, Margot Zielinska-Skowronek, Reinhold E Schmidt, Dirk Meyer-Olson

Publikováno v: PLoS ONE, Vol 7, Iss 9, p e44820 (2012)

NK cells are pivotal sentinels of the innate immune system and distinct subpopulations in peripheral blood have been described. A number of studies addressed HIV-induced alterations of NK cell phenotype and functionality mainly focusing on CD56(dim)C

Externí odkaz: https://doaj.org/article/6596dd184b4947d28432e44552a7c71b

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HCV-specific CD4+ T cells of patients with acute and chronic HCV infection display high expression of TIGIT and other co-inhibitory molecules

Autor: Silke Kummer, William W. Kwok, Thomas Jacobs, Julian Schulze zur Wiesch, Ansgar W. Lohse, Sven Peine, Matthias Marget, Tobias Boettler, Christin Ackermann, Thomas Kuntzen, Robin Woost, Maike Smits, Johanna M. Eberhard

Publikováno v: Scientific Reports, Vol 9, Iss 1, Pp 1-12 (2019)
Scientific Reports

The combined regulation of a network of inhibitory and activating T cell receptors may be a critical step in the development of chronic HCV infection. Ex vivo HCV MHC class I + II tetramer staining and bead-enrichment was performed with baseline and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df54b52b1f824ed57f6415d962a118ea
http://link.springer.com/article/10.1038/s41598-019-47024-8

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Decreased Frequency of Intestinal CD39+ γδ+ T Cells With Tissue-Resident Memory Phenotype in Inflammatory Bowel Disease

Autor: Jana Libera, Melanie Wittner, Marcus Kantowski, Robin Woost, Johanna M. Eberhard, Jocelyn de Heer, Dominik Reher, Samuel Huber, Friedrich Haag, Julian Schulze zur Wiesch

Publikováno v: Frontiers in Immunology, Vol 11 (2020)
Frontiers in Immunology

The ectoenzymes CD39 and CD73 play a major role in controlling tissue inflammation by regulating the balance between adenosine triphosphate (ATP) and adenosine. Still, little is known about the role of these two enzymes and ATP and its metabolites in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83061d201242347a87f57333e82ce00b
https://www.frontiersin.org/article/10.3389/fimmu.2020.567472/full

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Characterization of the immune cell landscape of patients with NAFLD

Autor: Andreas Drolz, Veronika Schlicker, Johannes Kluwe, Johanna M. Eberhard, Silke Kummer, Tom Diedrich, Julian Schulze zur Wiesch, Ansgar W. Lohse, A Galante

Publikováno v: PLoS ONE, Vol 15, Iss 3, p e0230307 (2020)
PLoS ONE

Multiple factors are involved in the pathogenesis of non-alcoholic fatty liver disease (NAFLD), but the exact immunological mechanisms that cause inflammation and fibrosis of the liver remain enigmatic. In this current study, cellular samples of a co

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ffeb3028b008b75e373e29081499dc22
https://doaj.org/article/7fd18f23a4be413c861b446dc162f973

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Brief Report: Increased Frequency of CD39+ CD56bright Natural Killer Cells in HIV-1 Infection Correlates With Immune Activation and Disease Progression

Autor: Julian Schulze zur Wiesch, Olaf Degen, Jan van Lunzen, Patrick Dierks, Sebastian Lunemann, Raluca Wroblewski, Ansgar W. Lohse, Anja Hüfner, Marcus Altfeld, Sandra Hertling, Johanna M. Eberhard, Stefan Schmiedel, Gloria Martrus

Publikováno v: JAIDS Journal of Acquired Immune Deficiency Syndromes. 74:467-472

The expression pattern of the ectonucleotidases CD39 and CD73 on natural killer (NK) cells was examined in peripheral blood mononuclear cell of 61 HIV-1-infected patients. Increased frequencies of CD39CD56 NK cells were detectable in untreated HIV pa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2060ccb9f33c3db75d0b8dddeeb3ec95
https://doi.org/10.1097/qai.0000000000001266

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Vulnerability to reservoir reseeding due to high immune activation after allogeneic hematopoietic stem cell transplantation in individuals with HIV-1

Publikováno v: Science Translational Medicine
Science Translational Medicine, American Association for the Advancement of Science, 2020, 12 (542), pp.eaay9355. ⟨10.1126/scitranslmed.aay9355⟩
Science Translational Medicine, 2020, 12 (542), pp.eaay9355. ⟨10.1126/scitranslmed.aay9355⟩
r-IGTP. Repositorio Institucional de Producción Científica del Instituto de Investigación Germans Trias i Pujol
instname

International audience; Allogeneic hematopoietic stem cell transplantation (allo-HSCT) is the only medical intervention that has led to an HIV cure. Whereas the HIV reservoir sharply decreases after allo-HSCT, the dynamics of the T cell reconstitutio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f34b7ac34f9190c00d84dbdcd7a104a9
https://pubmed.ncbi.nlm.nih.gov/32376772

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