Zobrazeno 1 - 10
of 52
pro vyhledávání: '"Johanna L. Höög"'
Autor:
Verena Kohler, Andreas Kohler, Lisa Larsson Berglund, Xinxin Hao, Sarah Gersing, Axel Imhof, Thomas Nyström, Johanna L. Höög, Martin Ott, Claes Andréasson, Sabrina Büttner
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-20 (2024)
Abstract The resilience of cellular proteostasis declines with age, which drives protein aggregation and compromises viability. The nucleus has emerged as a key quality control compartment that handles misfolded proteins produced by the cytosolic pro
Externí odkaz:
https://doaj.org/article/5dbf4037911449959b5703bfa8fbcbd3
Autor:
Katharina S. Keuenhof, Verena Kohler, Filomena Broeskamp, Dimitra Panagaki, Sean D. Speese, Sabrina Büttner, Johanna L. Höög
Publikováno v:
Nucleus, Vol 14, Iss 1 (2023)
ABSTRACTThe nuclear pore complex (NPC) has long been assumed to be the sole route across the nuclear envelope, and under normal homeostatic conditions it is indeed the main mechanism of nucleo-cytoplasmic transport. However, it has also been known th
Externí odkaz:
https://doaj.org/article/4b7bb68c77f04a0bb213452995631ac2
Autor:
Mario Ruiz, Ranjan Devkota, Dimitra Panagaki, Per-Olof Bergh, Delaney Kaper, Marcus Henricsson, Ali Nik, Kasparas Petkevicius, Johanna L. Höög, Mohammad Bohlooly-Y, Peter Carlsson, Jan Borén, Marc Pilon
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-19 (2022)
Cells and organisms requires proper membrane composition, which the cell must modulate as membrane lipids are primary acquired from the diet. Here, Ruiz et al. identify a conserved pathway connecting the fluidity regulators AdipoR1/2 with fatty acid
Externí odkaz:
https://doaj.org/article/bf10f952953b4afda5ebc346e710e1c3
Publikováno v:
Journal of Lipid Research, Vol 64, Iss 3, Pp 100335- (2023)
Externí odkaz:
https://doaj.org/article/e0c0d8ac4d2e46a49444c329b188373c
Autor:
Frederik Eisele, Anna Maria Eisele-Bürger, Xinxin Hao, Lisa Larsson Berglund, Johanna L. Höög, Beidong Liu, Thomas Nyström
Publikováno v:
Cell Reports, Vol 35, Iss 13, Pp 109328- (2021)
Summary: In this paper, we show that the essential Hsp90 co-chaperone Sgt1 is a member of a general protein quality control network that links folding and degradation through its participation in the degradation of misfolded proteins both in the cyto
Externí odkaz:
https://doaj.org/article/10d8f3ae433d4bc2bc959b564eba6d35
Autor:
Rossella Crescitelli, Cecilia Lässer, Su Chul Jang, Aleksander Cvjetkovic, Carina Malmhäll, Nasibeh Karimi, Johanna L. Höög, Iva Johansson, Johannes Fuchs, Annika Thorsell, Yong Song Gho, R. Olofsson Bagge, Jan Lötvall
Publikováno v:
Journal of Extracellular Vesicles, Vol 9, Iss 1 (2020)
The majority of extracellular vesicle (EV) studies conducted to date have been performed on cell lines with little knowledge on how well these represent the characteristics of EVs in vivo. The aim of this study was to establish a method to isolate an
Externí odkaz:
https://doaj.org/article/8cfb947702ee475d9e65bcbc4f8eb2b0
Autor:
Johanna L. Höög, Jan Lötvall
Publikováno v:
Journal of Extracellular Vesicles, Vol 4, Iss 0, Pp 1-11 (2015)
Human ejaculates contain extracellular vesicles (EVs), that to a large extent are considered to originate from the prostate gland, and are often denominated “prostasomes.” These EVs are important for human fertility, for example by promoting sper
Externí odkaz:
https://doaj.org/article/0a1d4c9a06d34102a3cbfd9f7cd9aa77
Autor:
Simon Stenberg, Jing Li, Arne B Gjuvsland, Karl Persson, Erik Demitz-Helin, Carles González Peña, Jia-Xing Yue, Ciaran Gilchrist, Timmy Ärengård, Payam Ghiaci, Lisa Larsson-Berglund, Martin Zackrisson, Silvana Smits, Johan Hallin, Johanna L Höög, Mikael Molin, Gianni Liti, Stig W Omholt, Jonas Warringer
Publikováno v:
eLife, Vol 11 (2022)
Deletion of mitochondrial DNA in eukaryotes is currently attributed to rare accidental events associated with mitochondrial replication or repair of double-strand breaks. We report the discovery that yeast cells arrest harmful intramitochondrial supe
Externí odkaz:
https://doaj.org/article/9ea3553d5dbd4ff5a143c35c07fe44a9
Publikováno v:
Acta Physiologica.
Autor:
Irene Álvarez-Guerra, Emma Block, Filomena Broeskamp, Sonja Gabrijelčič, Ana de Ory, Lukas Habernig, Claes Andréasson, Tim P. Levine, Johanna L. Höög, Sabrina Büttner
SummaryLipid droplets (LDs) are fat storage organelles critical for energy and lipid metabolism. Upon nutrient exhaustion, cells consume LDs via gradual lipolysis or via lipophagy, theen blocuptake of LDs into the vacuole. Here, we show that LDs dock
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2b26680096546e5f072dd1c6d746267b
https://doi.org/10.1101/2023.04.21.537797
https://doi.org/10.1101/2023.04.21.537797