Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Johanna Kastl"'
Autor:
Lillie E. Bell, Catherine Bardelle, Martin J Packer, Johanna Kastl, Geoffrey A. Holdgate, Gareth Davies
Publikováno v:
SLAS Discovery, Vol 29, Iss 5, Pp 100162- (2024)
Targeted protein degradation is an important mechanism carried out by the cellular machinery, one that is gaining momentum as an exploitable strategy for the development of drug-like compounds. Molecules which are able to induce proximity between elu
Externí odkaz:
https://doaj.org/article/87c376105ba44a24bea894a2940bb6bd
Publikováno v:
Methods in Molecular Biology ISBN: 9781493935406
Mitotic motor proteins of the kinesin superfamily are critical for the faithful segregation of chromosomes and the formation of the two daughter cells during meiotic and mitotic M-phase. Of the 45 human kinesins, roughly a dozen are involved in the a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::591b03d7891b5d7eed1fab3dc2a1118c
https://doi.org/10.1007/978-1-4939-3542-0_18
https://doi.org/10.1007/978-1-4939-3542-0_18
The genetic integrity of each organism depends on the faithful segregation of its genome during mitosis. To meet this challenge, a cellular surveillance mechanism, termed the spindle assembly checkpoint (SAC), evolved that monitors the correct attach
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92b444028e23f2bdc2628c745fe8b582
https://publishup.uni-potsdam.de/frontdoor/index/index/docId/38784
https://publishup.uni-potsdam.de/frontdoor/index/index/docId/38784
Publikováno v:
Developmental biology. 333(2)
Cyclin J is a cyclin family member that appears to have evolved before the metazoan radiation. Its evolutionary conservation argues for an important role but functional characterizations of Cyclin J have remained very limited. In Drosophila, Cyclin J
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e63b9d1e666776ccefcfa83e4d181e8a
https://pubmed.ncbi.nlm.nih.gov/19591820
https://pubmed.ncbi.nlm.nih.gov/19591820