Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Johanna Kölbel"'
Publikováno v:
Analytical Chemistry. 94:1713-1716
A versatile setup based on a microfluidics platform allows investigation of liquid samples at various temperatures with terahertz time-domain spectroscopy. The set up is applied to develop a novel method that performs temperature and concentration ca
Autor:
Amberley D. Stephens, Johanna Kölbel, Rani Moons, Chyi Wei Chung, Michael T. Ruggiero, Najet Mahmoudi, Talia A. Shmool, Thomas M. McCoy, Daniel Nietlispach, Alexander F. Routh, Frank Sobott, J. Axel Zeitler, Gabriele S. Kaminski Schierle
Publikováno v:
Angewandte Chemie: international edition in English
The solvation shell is essential for the folding and function of proteins, but how it contributes to protein misfolding and aggregation has still to be elucidated. We show that the mobility of solvation shell H2O molecules influences the aggregation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b44cbead7c121db4099de2660cf4a4a
The model glass-former glycerol and its aqueous mixtures were investigated with terahertz-time domain spectroscopy (THz-TDS) in the frequency range of 0.3--3.0\,THz at temperatures from 80--305\,K. It was shown that the infrared absorption coefficien
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b65587667f55170134d13eb45f008c0
http://arxiv.org/abs/2210.08032
http://arxiv.org/abs/2210.08032
A versatile setup based on terahertz time-domain spectroscopy was developed to monitor the process of crystallisation and characterise the structure of the crystals as well as the dynamics of the solvent in situ. The setup can be used to investigate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ac5f30525428042b3961e80f6f96202
https://doi.org/10.26434/chemrxiv-2021-mnchm
https://doi.org/10.26434/chemrxiv-2021-mnchm
Publikováno v:
2021 46th International Conference on Infrared, Millimeter and Terahertz Waves (IRMMW-THz).
The crystallisation process of MgSO 4 in a crystallisation cell is investigated at different temperatures and concentrations by combining terahertz time-domain spectroscopy with optical analysis. The emergence and change of a spectral feature at 1.6
Autor:
Frank Sobott, Johanna Kölbel, J. Axel Zeitler, Talia A. Shmool, Gabriele S. Kaminski Schierle, Rani Moons, Amberley D. Stephens, Daniel Nietlispach, Alexander F. Routh, Thomas M. McCoy, Najet Mahmoudi, Michael T. Ruggerio
The propensity for intrinsically disordered proteins to aggregate is heavily influenced by their surrounding environment. Here, we show that the mobility of the surrounding water molecules directly influences the aggregation rate of α-synuclein (aSy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5fd95c4b4565b42a65188750adf202e5
https://doi.org/10.1101/2021.01.06.425575
https://doi.org/10.1101/2021.01.06.425575
Autor:
Johanna Kölbel, J. A. Zeitler
Publikováno v:
2019 44th International Conference on Infrared, Millimeter, and Terahertz Waves (IRMMW-THz).
The stability of freeze-dried formulations due to residual water is a topic of significant interest. Glycerol, a cryoprotectant that is widely used in freeze drying, is mixed with water in different concentrations and measured with terahertz time-dom
Publikováno v:
2018 43rd International Conference on Infrared, Millimeter, and Terahertz Waves (IRMMW-THz).
The nature of the low-frequency vibrational motions occurring within disordered solids has been a topic of great debate of the last several decades. Using a combination of experimental terahertz time-domain spectroscopy and state-of-the-art quantum m