Osimertinib Plasma Trough Concentration in Relation to Brain Metastases Development in Patients With Advanced EGFR-Mutated NSCLC

Autor: Judith L. Gulikers, MSc, G.D. Marijn Veerman, MD, PhD, Merel Jebbink, MD, PhD, Paul D. Kruithof, PharmD, Christi M.J. Steendam, MD, PhD, René J. Boosman, PhD, Ron H.J. Mathijssen, MD, PhD, Vivianne C.G. Tjan-Heijnen, MD, PhD, Johanna H.M. Driessen, PhD, Safiye Dursun, MD, Egbert F. Smit, MD, PhD, Anne-Marie C. Dingemans, MD, PhD, Robin M.J.M. van Geel, PharmD, PhD, Sander Croes, PharmD, PhD, Lizza E.L. Hendriks, MD, PhD

Publikováno v: JTO Clinical and Research Reports, Vol 5, Iss 4, Pp 100656- (2024)

Introduction: Brain metastases (BM) are common in patients with advanced EGFR-mutated (EGFRm+) NSCLC. Despite good BM-related outcomes of osimertinib, several patients still experience intracranial progression. A possible explanation is pharmacologic

Externí odkaz: https://doaj.org/article/b8cb56c1a21d4838abe7a2a929f0a009

Use of sodium-glucose co-transporter 2 inhibitors, changes in body mass index and risk of fracture: A population-based cohort study

Autor: Judith van Dalem, Nikki C.C. Werkman, Joop P. van den Bergh, Bernardette Rossi, Rikke Viggers, Richard Eastell, Andrea M. Burden, Coen D.A. Stehouwer, Olaf H. Klungel, Martijn C.G.J. Brouwers, Johanna H.M. Driessen

Publikováno v: Diabetes Research and Clinical Practice, 190
Diabetes Research and Clinical Practice, 190:109993. Elsevier Ireland Ltd
van Dalem, J, Cc Werkman, N, van den Bergh, J P, Rossi, B, Viggers, R, Eastell, R, Burden, A M, DA Stehouwer, C, Klungel, O H, Cgj Brouwers, M & Hm Driessen, J 2022, ' Use of sodium-glucose co-transporter 2 inhibitors, changes in body mass index and risk of fracture : A population-based cohort study ', Diabetes Research and Clinical Practice, vol. 190, 109993 . https://doi.org/10.1016/j.diabres.2022.109993

Aims: Sodium-glucose co-transporter-2 (SGLT-2) inhibitor-induced weight loss might play a role in the debated elevated fracture risk with these agents. The aim of the current study was to investigate the association between SGLT-2 inhibitor use, chan

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27ab202ea241c5e587b6059375cfe987
https://hdl.handle.net/20.500.11850/566903

Blood Eosinophil Counts, Withdrawal of Inhaled Corticosteroids and Risk of COPD Exacerbations and Mortality in the Clinical Practice Research Datalink (CPRD).

Autor: Oshagbemi, Olorunfemi A.^1,2,3,4 (AUTHOR), Franssen, Frits M.E.^4,5 (AUTHOR), van Kraaij, Suzanne¹ (AUTHOR), Braeken, Dionne C.W.^3,4,5 (AUTHOR), Wouters, Emiel F.M.^4,6 (AUTHOR), Maitland-van der Zee, Anke H.^3,6 (AUTHOR), Driessen, Johanna H.M.^1,3,7 (AUTHOR), de Vries, Frank^1,2,3 (AUTHOR) f.devries@uu.nl

Publikováno v: COPD: Journal of Chronic Obstructive Pulmonary Disease. Apr2019, Vol. 16 Issue 2, p152-159. 8p.

Secular trends in major osteoporotic fractures among 50+ adults in Denmark between 1995 and 2010.

Autor: Abtahi, Shahab, Driessen, Johanna H.M., Vestergaard, Peter, van den Bergh, Joop, Boonen, Annelies, de Vries, Frank, Burden, Andrea M.

Publikováno v: Osteoporosis International; Nov2019, Vol. 30 Issue 11, p2217-2223, 7p, 1 Chart, 2 Graphs

Vertebral bone attenuation in Hounsfield Units and prevalent vertebral fractures are associated with the short-term risk of vertebral fractures in current and ex-smokers with and without COPD: a 3-year chest CT follow-up study.

Autor: van Dort, M.J., Driessen, J.H.M., Geusens, P., Romme, E.A.P.M., Smeenk, F.W.J.M., Wouters, E.F.M., van den Bergh, J.P.W.

Publikováno v: Osteoporosis International; Aug2019, Vol. 30 Issue 8, p1561-1571, 11p, 1 Diagram, 4 Charts, 1 Graph