Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Johanna Gassler"'
Autor:
Bart J. H. Dequeker, Matthias J. Scherr, Hugo B. Brandão, Johanna Gassler, Sean Powell, Imre Gaspar, Ilya M. Flyamer, Aleksandar Lalic, Wen Tang, Roman Stocsits, Iain F. Davidson, Jan-Michael Peters, Karl E. Duderstadt, Leonid A. Mirny, Kikuë Tachibana
Publikováno v:
Nature
Eukaryotic genomes are compacted into loops and topologically associating domains (TADs)1–3, which contribute to transcription, recombination and genomic stability4,5. Cohesin extrudes DNA into loops that are thought to lengthen until CTCF boundari
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9fc53de26f6a5b4349e849f02bf18469
https://doi.org/10.1038/s41586-022-04730-0
https://doi.org/10.1038/s41586-022-04730-0
Autor:
Johanna Gassler, Wataru Kobayashi, Imre Gáspár, Siwat Ruangroengkulrith, Maximilian Kümmecke, Pavel Kravchenko, Maciej Zaczek, Antoine Vallot, Laura Gomez Hernandez, Laura Cuenca Rico, Sabrina Ladstätter, Kikuë Tachibana
Life begins with a switch in genetic control from the maternal to the embryonic genome during zygotic genome activation (ZGA) in totipotent embryos. Despite its importance, the essential regulators of ZGA remain largely unknown in mammals. Based on d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a852e90ecdae918579b3a2c53750cb21
https://doi.org/10.1101/2022.05.17.492379
https://doi.org/10.1101/2022.05.17.492379
Autor:
Kikuë Tachibana, Sean Powell, Johanna Gassler, Mariana C C Silva, Emmanouella E. Chatzidaki, Bart J. H. Dequeker
Publikováno v:
Current Biology
The frequency of egg aneuploidy and trisomic pregnancies increases with maternal age. To what extent individual approaches can delay the "maternal age effect" is unclear because multiple causes contribute to chromosomal abnormalities in mammalian egg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2204fc68faf32f953954b517fde2a3fe
https://hdl.handle.net/21.11116/0000-0009-A01E-121.11116/0000-0009-A020-D21.11116/0000-0009-A021-C
https://hdl.handle.net/21.11116/0000-0009-A01E-121.11116/0000-0009-A020-D21.11116/0000-0009-A021-C
Autor:
Bart J H, Dequeker, Matthias J, Scherr, Hugo B, Brandão, Johanna, Gassler, Sean, Powell, Imre, Gaspar, Ilya M, Flyamer, Aleksandar, Lalic, Wen, Tang, Roman, Stocsits, Iain F, Davidson, Jan-Michael, Peters, Karl E, Duderstadt, Leonid A, Mirny, Kikuë, Tachibana
Publikováno v:
Nature. 606(7912)
Eukaryotic genomes are compacted into loops and topologically associating domains (TADs)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::961beeeb58e90d64528b5c198c67dedc
https://pubmed.ncbi.nlm.nih.gov/35868255
https://pubmed.ncbi.nlm.nih.gov/35868255
Autor:
Sean Powell, Ilya M. Flyamer, Jan-Michael Peters, Matthias J. Scherr, Wen Tang, Kikuё Tachibana, Karl E. Duderstadt, Bart J. H. Dequeker, Hugo B. Brandão, Iain F. Davidson, Imre Gaspar, Roman R. Stocsits, Johanna Gassler, Leonid A. Mirny
Publikováno v:
bioRxiv
Eukaryotic genomes are compacted into loops and topologically associating domains (TADs), which contribute to transcription, recombination and genomic stability. Cohesin extrudes DNA into loops that are thought to lengthen until CTCF boundaries are e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e698e812f094fd4d44684eb230da516c
https://doi.org/10.1101/2020.10.15.340356
https://doi.org/10.1101/2020.10.15.340356
Autor:
Qing-Yuan Sun, Wan Kin Au Yeung, Zili Lin, Yujie Sun, Aibin He, Nathalie Véron, Hui Zheng, Bo Huang, Kikuë Tachibana, Ling Liu, Hiroyuki Sasaki, Antoine H.F.M. Peters, Peizhe Wang, Wei Xie, Qiujun Wang, Yumiko K Kawamura, Zhenhai Du, Evgeniy A. Ozonov, Kai Xu, Ke Zhang, Sean Powell, Jie Na, Guang Yu, Lijia Li, Qian Zhou, Lei Chang, Johanna Gassler, Qianhua Xu
Publikováno v:
Molecular Cell
Summary In mammals, chromatin organization undergoes drastic reorganization during oocyte development. However, the dynamics of three-dimensional chromatin structure in this process is poorly characterized. Using low-input Hi-C (genome-wide chromatin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4771ca7107b0937e4e247ab91a7468b9
Autor:
Kikuë Tachibana-Konwalski, Maxim Imakaev, Ilya M. Flyamer, Johanna Gassler, Nezar Abdennur, Sergey V. Razin, Hugo B. Brandão, Sergey V. Ulianov, Leonid A. Mirny
Publikováno v:
Nature
Chromatin is reprogrammed after fertilization to produce a totipotent zygote with the potential to generate a new organism. The maternal genome inherited from the oocyte and the paternal genome provided by sperm coexist as separate haploid nuclei in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8869773493c95d6f60bf1adbec837573
http://europepmc.org/articles/PMC5639698
http://europepmc.org/articles/PMC5639698
Autor:
Jan-Michael Peters, Mariana C C Silva, Kikuë Tachibana, Antonio Tedeschi, Roman R. Stocsits, Johanna Gassler, Sabrina Ladstätter, Sean Powell
Publikováno v:
The Journal of Cell Biology
Journal of Cell Biology
Journal of Cell Biology
Silva et al. demonstrate that distinct cohesin complexes are essential for sister chromatid cohesion and genome folding in mammalian oocytes. Scc1-cohesin is required for chromatin loops while Rec8-cohesin mediates bivalent cohesion. Wapl-mediated re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6306d34cf6c0b4310aef95591572fb82
https://pubmed.ncbi.nlm.nih.gov/32328639
https://pubmed.ncbi.nlm.nih.gov/32328639
Publikováno v:
Methods in cell biology. 144
The 3D folding of the genome is linked to essential nuclear processes including gene expression, DNA repair, and replication. Chromatin conformation capture assays such as Hi-C are providing unprecedented insights into higher-order chromatin structur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::885e19169afe6e00508f990bc97fb410
https://pubmed.ncbi.nlm.nih.gov/29804679
https://pubmed.ncbi.nlm.nih.gov/29804679
The 3D folding of the genome is linked to essential nuclear processes including gene expression, DNA repair, and replication. Chromatin conformation capture assays such as Hi-C are providing unprecedented insights into higher-order chromatin structur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cd754492e6b384f06066375616e8c76e
https://doi.org/10.1016/bs.mcb.2018.03.032
https://doi.org/10.1016/bs.mcb.2018.03.032