Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Johanna Flygt"'
Publikováno v:
Frontiers in Neurology, Vol 15 (2024)
IntroductionTraumatic brain injury to thalamo-cortical pathways is associated with posttraumatic morbidity. Diffuse mechanical forces to white matter tracts and deep grey matter regions induce an inflammatory response and vascular damage resulting in
Externí odkaz:
https://doaj.org/article/03b76f2972d3426d841fbc09646c9a1b
Autor:
Anders Hånell, Hans W. Axelson, Anders Djupsjö, Niklas Marklund, Tomas Winkler, Johanna Flygt
Publikováno v:
Restorative Neurology and Neuroscience. 31:73-85
Recovery is limited following traumatic brain injury (TBI) since injured axons regenerate poorly and replacement of lost cells is minimal. Behavioral improvements could instead be due to plasticity of uninjured brain regions. We hypothesized that pla
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9c7924282d634a696f237b9231d7f06
https://doi.org/10.3233/rnn-2012-120242
https://doi.org/10.3233/rnn-2012-120242
Autor:
Johanna Flygt, Jonatan Holm, Karin Skoglund, Martin Ingelsson, Niklas Marklund, Irina Alafuzoff, Astrid Gumucio
Publikováno v:
Journal of neuropathology and experimental neurology. 75(6)
Oligodendrocyte (OL) death may contribute to white matter pathology, a common cause of network dysfunction and persistent cognitive problems in patients with traumatic brain injury (TBI). Oligodendrocyte progenitor cells (OPCs) persist throughout the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c07708539cff51ac17c9fbf32e3ba7c9
https://pubmed.ncbi.nlm.nih.gov/27105664
https://pubmed.ncbi.nlm.nih.gov/27105664
Autor:
Olivia Kiwanuka, Anders Hånell, Bengt J. Meyerson, Fredrik Clausen, Sara Ekmark-Lewén, Lars Hillered, Hermann Gram, Gudrun A Fridgeirsdottir, Anders Lewén, Anis Mir, Johanna Flygt, Niklas Marklund
Publikováno v:
The European journal of neuroscience. 43(8)
Widespread traumatic axonal injury (TAI) results in brain network dysfunction, which commonly leads to persisting cognitive and behavioural impairments following traumatic brain injury (TBI). TBI induces a complex neuroinflammatory response, frequent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65e3d3be8d0a81199b45d7d62554ea13
https://pubmed.ncbi.nlm.nih.gov/27091435
https://pubmed.ncbi.nlm.nih.gov/27091435
Autor:
Johanna Flygt, Henrik Bengtsson, Olivia Kiwanuka, Niklas Marklund, Elaine Astrand, Charlotte Israelsson
Publikováno v:
Restorative neurology and neuroscience. 32(5)
When central nervous system axons are injured, regeneration is partly inhibited by myelin-associated inhibitors (MAIs). Following traumatic brain injury (TBI) in the rat, pharmacological neutralisation of the MAIs Nogo-A and myelin-associated glycopr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff7c624fe124b0c6dd4cf6f81955a7da
https://pubmed.ncbi.nlm.nih.gov/25079982
https://pubmed.ncbi.nlm.nih.gov/25079982
Autor:
Parmenion P. Tsitsopoulos, Henrik Engquist, Johanna Flygt, Karin Skoglund, Per Enblad, Niklas Marklund, Anders Lewén, Karlis Purins, Lars Hillered
Publikováno v:
Neurocritical care. 20(3)
The neurological wake-up test (NWT) is used to monitor the level of consciousness in patients with traumatic brain injury (TBI). However, it requires interruption of sedation and may elicit a stress response. We evaluated the effects of the NWT using
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59b55848df54c223d66f32a6a6ae0f55
https://pubmed.ncbi.nlm.nih.gov/23934408
https://pubmed.ncbi.nlm.nih.gov/23934408
Autor:
Johanna Flygt, Lars Hillered, Niklas Marklund, Olivia Kiwanuka, Bengt J. Meyerson, Sara Ekmark-Lewén, Anders Lewén
Publikováno v:
Journal of Neuroinflammation
Background Diffuse traumatic axonal injury (TAI), a common consequence of traumatic brain injury, is associated with high morbidity and mortality. Inflammatory processes may play an important role in the pathophysiology of TAI. In the central fluid p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44a9d758dc8b8eb6793051ae94f57421
https://doi.org/10.1186/1742-2094-10-44
https://doi.org/10.1186/1742-2094-10-44
Publikováno v:
The European journal of neuroscience. 38(1)
Axonal injury is an important contributor to the behavioral deficits observed following traumatic brain injury (TBI). Additionally, loss of myelin and/or oligodendrocytes can negatively influence signal transduction and axon integrity. Apoptotic olig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7bce32a88445c8d1ea0d5fff2cf542d
https://pubmed.ncbi.nlm.nih.gov/23458840
https://pubmed.ncbi.nlm.nih.gov/23458840