Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Johanna Fitz"'
Autor:
Julia Costea, Ursula E. Schoeberl, Daniel Malzl, Maximilian von der Linde, Johanna Fitz, Ankit Gupta, Marina Makharova, Anton Goloborodko, Rushad Pavri
Publikováno v:
Molecular Cell. 83:681-697.e7
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::62a2207731552ecadbd3ad2d828c8123
https://doi.org/10.1016/j.molcel.2023.01.014
https://doi.org/10.1016/j.molcel.2023.01.014
Autor:
Ursula E. Schoeberl, Johanna Fitz, Kimon Froussios, Renan Valieris, Iordanis Ourailidis, Marina Makharova, Bernd Bauer, Tobias Neumann, Eva-Maria Wiedemann, Monika Steininger, Adriana Cantoran Garcia, Marialaura Mastrovito, Hugo Mouquet, Israel Tojal Da Silva, Rushad Pavri
Somatic hypermutation (SHM) of immunoglobulin variable (V) regions modulates antibody-antigen affinity is initiated by activation-induced cytidine deaminase (AID) on single-stranded DNA (ssDNA). Transcription is essential for SHM and AID target genes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e6f750038b8e6c0df818c77b19b242ec
https://doi.org/10.1101/2022.05.21.492925
https://doi.org/10.1101/2022.05.21.492925
Autor:
Julia Costea, Ursula E. Schoeberl, Daniel Malzl, Maximilian von der Linde, Johanna Fitz, Marina Makharova, Anton Goloborodko, Rushad Pavri
Conflicts between transcription and cohesin-mediated loop extrusion can majorly influence 3D chromatin architecture but whether these structural changes affect biological function is unknown. Here, we show that a critical step in antibody class switc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1d7652ff41617fe8a7ef7cfd819272e0
https://doi.org/10.1101/2022.04.26.489407
https://doi.org/10.1101/2022.04.26.489407
Autor:
Alexander Athanasiadis, Monika Steininger, Johanna Fitz, Rushad Pavri, Adriana Cantoran Garcia, Eva-Maria Wiedemann, Ursula E. Schoeberl, Tobias Neumann
Publikováno v:
Nature Genetics. 52:505-515
Active enhancers are frequently transcribed, yet the regulatory role of enhancer transcription remains debated. Here, we depleted the RNA polymerase II pausing and elongation factor Spt5 in activated mouse B cells and found that approximately 50% of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::04f0ba2e9e3c32d021da5495888baf07
https://doi.org/10.1038/s41588-020-0605-6
https://doi.org/10.1038/s41588-020-0605-6
Autor:
Ursula E. Schoeberl, Johanna Fitz, Kimon Froussios, Renan Valieris, Marina Makharova, Iordanis Ourailidis, Bernd Bauer, Tobias Neumann, Eva-Maria Wiedemann, Monika Steininger, Adriana Cantoran Garcia, Marialaura Mastrovito, Hugo Mouquet, Israel Tojal da Silva, Rushad Pavri
Publikováno v:
SSRN Electronic Journal.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7dd5b1c53b042c98e68c9c5cd9881a87
https://doi.org/10.2139/ssrn.4137693
https://doi.org/10.2139/ssrn.4137693
Publikováno v:
International Journal of Qualitative Methods, Vol 23 (2024)
Article 12 of the United Nations Convention of the Rights of the Child (UNCRC) (1989) sets out the right for all children to be heard and for their opinions to be given due weight. However, the voices of children with disabilities often remain silenc
Externí odkaz:
https://doaj.org/article/c5b9d3fc25a446ac99f5d671b3006ffa
Autor:
Emma Sweeney, Johanna Fitzgerald
Publikováno v:
Disabilities, Vol 3, Iss 3, Pp 379-395 (2023)
Radical transformation of Ireland’s special education system has occurred over the past three decades. National and international policy and legislative drivers for a more inclusive approach to education have resulted in greater levels of mainstrea
Externí odkaz:
https://doaj.org/article/32ea55c3e77e491d84a8e2b83083cf08
Publikováno v:
The EMBO Journal
Spt5 is a highly conserved RNA polymerase II (Pol II)‐associated pausing and elongation factor. However, its impact on global elongation and Pol II processivity in mammalian cells has not been clarified. Here, we show that depleting Spt5 in mouse e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7fdf46c876f8652d0bb21be2cfadcd8
http://europepmc.org/articles/PMC5897773
http://europepmc.org/articles/PMC5897773
Publikováno v:
PLoS ONE, Vol 18, Iss 6 (2023)
Background Ten percent of the school-aged population have speech, language, and communication needs (SLCN) that impact access to the curriculum. Successful implementation of classroom-based SLCN interventions can reduce barriers to learning, thereby
Externí odkaz:
https://doaj.org/article/c0f619f525884fe2b35e73b2cb0986b1
Autor:
Maria Holland, Johanna Fitzgerald
Publikováno v:
Education Sciences, Vol 13, Iss 3, p 286 (2023)
This research study explored barriers and facilitators to collaboration between National Educational Psychological Service (NEPS) psychologists, Special Educational Needs Co-ordinators (SENCOs), and Senior Leadership Teams (SLT) in Irish post-primary
Externí odkaz:
https://doaj.org/article/cdfd0ff2b86045639b12bf7628f97dc3