Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Johanna Eerola‐Rautio"'
Autor:
K. Amande M. Pauls, Jussi Toppila, Maija Koivu, Johanna Eerola‐Rautio, Marianne Udd, Eero Pekkonen
Publikováno v:
Brain and Behavior, Vol 11, Iss 12, Pp n/a-n/a (2021)
Abstract Objectives Levodopa‐carbidopa‐intestinal‐gel (LCIG) infusion is an effective treatment for advanced PD with motor fluctuations. Polyneuropathy occurs as a complication in 10–15% of patients. We wanted to assess the frequency of polyn
Externí odkaz:
https://doaj.org/article/7c32c7b323a5460dad343ae41756cdac
Autor:
Thomas G. McWilliams, Erica Barini, Risto Pohjolan-Pirhonen, Simon P. Brooks, François Singh, Sophie Burel, Kristin Balk, Atul Kumar, Lambert Montava-Garriga, Alan R. Prescott, Sidi Mohamed Hassoun, François Mouton-Liger, Graeme Ball, Rachel Hills, Axel Knebel, Ayse Ulusoy, Donato A. Di Monte, Jevgenia Tamjar, Odetta Antico, Kyle Fears, Laura Smith, Riccardo Brambilla, Eino Palin, Miko Valori, Johanna Eerola-Rautio, Pentti Tienari, Olga Corti, Stephen B. Dunnett, Ian G. Ganley, Anu Suomalainen, Miratul M. K. Muqit
Publikováno v:
Open Biology, Vol 8, Iss 11 (2018)
Mutations in PINK1 and Parkin result in autosomal recessive Parkinson's disease (PD). Cell culture and in vitro studies have elaborated the PINK1-dependent regulation of Parkin and defined how this dyad orchestrates the elimination of damaged mitocho
Externí odkaz:
https://doaj.org/article/1d714fdf77f7434a8620cf73ff0a6aee
Autor:
Henri J. Huttunen, Sigrid Booms, Magnus Sjögren, Vera Kerstens, Jarkko Johansson, Rebecka Holmnäs, Jani Koskinen, Natalia Kulesskaya, Patrik Fazio, Max Woolley, Alan Brady, Julia Williams, David Johnson, Narges Dailami, William Gray, Reeta Levo, Mart Saarma, Christer Halldin, Johan Marjamaa, Julio Resendiz‐Nieves, Irena Grubor, Göran Lind, Johanna Eerola‐Rautio, Tuomas Mertsalmi, Mattias Andréasson, Gesine Paul, Juha Rinne, Riku Kivisaari, Hjalmar Bjartmarz, Per Almqvist, Andrea Varrone, Filip Scheperjans, Håkan Widner, Per Svenningsson
Publikováno v:
Movement Disorders.
Background: Cerebral dopamine neurotrophic factor (CDNF) is an unconventional neurotrophic factor that protects dopamine neurons and improves motor function in animal models of Parkinson's disease (PD). Objective: The primary objectives of this study
Autor:
Maija Koivu, Filip Scheperjans, Johanna Eerola-Rautio, Nuutti Vartiainen, Julio Resendiz-Nieves, Riku Kivisaari, Eero Pekkonen
Publikováno v:
Journal of Personalized Medicine; Volume 12; Issue 8; Pages: 1224
Directional deep brain stimulation (dDBS) is preferred by patients with advanced Parkinson’s disease (PD) and by programming neurologists. However, real-life data of dDBS use is still scarce. We reviewed the clinical data of 53 PD patients with dDB
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ce1b2896bb909322b8b666934eb2133
http://hdl.handle.net/10138/347981
http://hdl.handle.net/10138/347981
Autor:
Lisa M. Shulman, Hirotaka Iwaki, David A. Hinds, Jacob Gratten, Huw R. Morris, Joseph Jankovic, Costanza L. Vallerga, J. Raphael Gibbs, John Hardy, Javier Simón-Sánchez, Johan Marinus, Thomas Gasser, Peter Heutink, Alexis Brice, Andrew B. Singleton, Dena G. Hernandez, Jean-Christophe Corvol, Karl Heilbron, Donald G. Grosset, Manu Sharma, Ari Siitonen, Peter M. Visscher, Sonja W. Scholz, Pentti J. Tienari, Lynne Krohn, Mathias Toft, Manuela Tan, Johanna Eerola-Rautio, Mike A. Nalls, Jacobus J. van Hilten, Lasse Pihlstrøm, Claudia Schulte, Ziv Gan-Or, Sara Bandres-Ciga, Cornelis Blauwendraat, Hampton L. Leonard, Alastair J. Noyce, Kari Majamaa, Rainer von Coelln, N Wood, Joshua M. Shulman, Suzanne Lesage
Publikováno v:
Movement disorders 34(6), 866-875 (2019). doi:10.1002/mds.27659
Mov Disord
Movement Disorders, 34(6), 866-875
Mov Disord
Movement Disorders, 34(6), 866-875
Background Increasing evidence supports an extensive and complex genetic contribution to PD. Previous genome-wide association studies (GWAS) have shed light on the genetic basis of risk for this disease. However, the genetic determinants of PD age at
Autor:
Johanna Eerola-Rautio, Eero Pekkonen, Tuomas Mertsalmi, Marianne Udd, Maija Koivu, Vili Viljaharju, K. Amande M. Pauls
Publikováno v:
Mov Disord Clin Pract
BACKGROUND: Levodopa‐carbidopa intestinal gel (LCIG) effectively reduces off time and dyskinesia and increases on time in advanced Parkinson's disease (PD). However, patients with LCIG‐infusion experience frequent complications and some discontin
Autor:
Andrew B. Singleton, Kathrin Brockmann, Ziv Gan-Or, Alexis Brice, Lynne Krohn, Ari Siitonen, Mike A. Nalls, Sara Bandres-Ciga, Donald G. Grosset, Alastair J. Noyce, Nicholas W. Wood, Hampton L. Leonard, Manuela Tan, Hirotaka Iwaki, Jennifer A. Ruskey, Jean-Christophe Corvol, Cornelis Blauwendraat, J. R. Gibbs, Francis P. Grenn, Mary B. Makarious, Jacobus J. van Hilten, Suzanne Lesage, Lasse Pihlstrøm, John Hardy, Peter Heutink, Huw R. Morris, Claudia Schulte, Kari Majamaa, Julie Lake, Thomas Gasser, Manu Sharma, Pentti J. Tienari, Johanna Eerola-Rautio, Jonggeol Jeff Kim, Mathias Toft, Johan Marinus, Dena G. Hernandez
Parkinson’s disease (PD) is a complex neurodegenerative disorder. Males are on average ∼1.5 times more likely to develop PD compared to females. Over the years genome-wide association studies (GWAS) have identified numerous genetic risk factors f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::674955606349d62a9e4f44b74ebccaf8
https://doi.org/10.1101/2021.02.09.21250262
https://doi.org/10.1101/2021.02.09.21250262
Autor:
Pablo Martinez-Martin, Glenn T. Stebbins, Jeffrey Lin, Jaana Korpela, Mika H. Martikainen, Eero Pekkonen, Johanna Eerola-Rautio, Katja Airaksinen, Jussi O.T. Sipilä, Valtteri Kaasinen, Anna Brück, Filip Scheperjans, Christopher G. Goetz, Juha T. Järvelä, Mikko Kärppä, Juho Joutsa, Sheng Luo
Publikováno v:
European neurology. 84(6)
Introduction: The Unified Dyskinesia Rating Scale (UDysRS) was developed to provide a comprehensive rating tool of dyskinesia in Parkinson’s disease (PD). Because dyskinesia therapy trials involve multicenter studies, having a scale that is validat
Autor:
Alan R. Prescott, Graeme Ball, Kyle Fears, Miratul M. K. Muqit, Pentti J. Tienari, Axel Knebel, Johanna Eerola-Rautio, Riccardo Brambilla, Sophie Burel, Lambert Montava-Garriga, Simon Philip Brooks, Odetta Antico, Anu Suomalainen, Ayse Ulusoy, Rachel Hills, Olga Corti, François Mouton-Liger, Eino Palin, Ian G. Ganley, Donato A. Di Monte, Kristin Balk, Jevgenia Tamjar, Thomas G. McWilliams, Laura Smith, François Singh, Stephen B. Dunnett, Risto Pohjolan-Pirhonen, Atul Kumar, Sidi Mohamed Hassoun, Erica Barini, Miko Valori
Publikováno v:
Open Biology
'Open Biology ', vol: 8, pages: 180108-1-180108-18 (2018)
Open biology 8(11), 180108 (2018). doi:10.1098/rsob.180108
Open Biology, Vol 8, Iss 11 (2018)
'Open Biology ', vol: 8, pages: 180108-1-180108-18 (2018)
Open biology 8(11), 180108 (2018). doi:10.1098/rsob.180108
Open Biology, Vol 8, Iss 11 (2018)
Mutations in PINK1 and Parkin result in autosomal recessive Parkinson's disease (PD). Cell culture and in vitro studies have elaborated the PINK1-dependent regulation of Parkin and defined how this dyad orchestrates the elimination of damaged mitocho