Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Johanna E. Lotsari"'
Autor:
Wael M. Abdel-Rahman, Johanna E. Lotsari-Salomaa, Sippy Kaur, Anni Niskakoski, Sakari Knuutila, Heikki Järvinen, Jukka-Pekka Mecklin, Päivi Peltomäki
Publikováno v:
Gastroenterology Research and Practice, Vol 2016 (2016)
All colorectal cancer cell lines except RKO displayed active β-catenin/TCF regulated transcription. This feature of RKO was noted in familial colon cancers; hence our aim was to dissect its carcinogenic mechanism. MFISH and CGH revealed distinct ins
Externí odkaz:
https://doaj.org/article/113647cdee7f46289f9e289e658fb994
Autor:
Wael M. Abdel-Rahman, Emmi I. Joensuu, Johanna E. Lotsari, Taina T. Nieminen, Päivi Peltomäki, Walter Hernán Pavicic
Publikováno v:
Genes, Chromosomes and Cancer. 54:776-787
Molecular mechanisms underlying coordinated hypermethylation of multiple CpG islands in cancer remain unclear and studies of methyltransferase enzymes have arrived at conflicting results. We focused on DNMT1 and DNMT3B, DNA methyltransferases respons
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::23c8dc15cf39ea68e8f7b509fcde0c29
https://doi.org/10.1002/gcc.22289
https://doi.org/10.1002/gcc.22289
Publikováno v:
Advances in experimental medicine and biology. 937
Epigenetic alterations such as DNA methylation, histone modifications and non-coding RNA (including microRNA) associated gene silencing have been identified as a major characteristic in human cancers. These alterations may occur more frequently than
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0a81964efc11aa3ae15cbe3f5160e75d
https://pubmed.ncbi.nlm.nih.gov/27573897
https://pubmed.ncbi.nlm.nih.gov/27573897
Publikováno v:
Advances in Experimental Medicine and Biology ISBN: 9783319420578
Epigenetic alterations such as DNA methylation, histone modifications and non-coding RNA (including microRNA) associated gene silencing have been identified as a major characteristic in human cancers. These alterations may occur more frequently than
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::73b13afe5e31c76e3f2fbb9fec0fa190
https://doi.org/10.1007/978-3-319-42059-2_6
https://doi.org/10.1007/978-3-319-42059-2_6
Autor:
Johanna E. Lotsari-Salomaa, Sakari Knuutila, Päivi Peltomäki, Heikki Järvinen, Sippy Kaur, Jukka-Pekka Mecklin, Anni Niskakoski, Wael M. Abdel-Rahman
Publikováno v:
Gastroenterology Research and Practice, Vol 2016 (2016)
Gastroenterology Research and Practice
Gastroenterology Research and Practice
Article
All colorectal cancer cell lines except RKO displayed active β-catenin/TCF regulated transcription. This feature of RKO was noted in familial colon cancers; hence our aim was to dissect its carcinogenic mechanism. MFISH and CGH revealed
All colorectal cancer cell lines except RKO displayed active β-catenin/TCF regulated transcription. This feature of RKO was noted in familial colon cancers; hence our aim was to dissect its carcinogenic mechanism. MFISH and CGH revealed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9edf22e2dc3d0b70ca54af263bd428e8
https://doaj.org/article/113647cdee7f46289f9e289e658fb994
https://doaj.org/article/113647cdee7f46289f9e289e658fb994
Autor:
Emmi I, Joensuu, Taina T, Nieminen, Johanna E, Lotsari, Walter, Pavicic, Wael M, Abdel-Rahman, Päivi, Peltomäki
Publikováno v:
Genes, chromosomescancer. 54(12)
Molecular mechanisms underlying coordinated hypermethylation of multiple CpG islands in cancer remain unclear and studies of methyltransferase enzymes have arrived at conflicting results. We focused on DNMT1 and DNMT3B, DNA methyltransferases respons
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e0b6ec2b0c06b40834ba82fede247785
https://pubmed.ncbi.nlm.nih.gov/26305882
https://pubmed.ncbi.nlm.nih.gov/26305882
Autor:
Taina T. Nieminen, Päivi Peltomäki, Kristiina Aittomäki, Markku Aarnio, Reino Pitkänen, Heikki Järvinen, Marjukka Friman, Jukka-Pekka Mecklin, Johanna E. Lotsari, Annette Gylling, Teijo Kuopio, Wael M. Abdel-Rahman
Publikováno v:
Breast Cancer Research : BCR
Introduction Breast carcinoma is the most common cancer in women, but its incidence is not increased in Lynch syndrome (LS) and studies on DNA mismatch repair deficiency (MMR) in LS-associated breast cancers have arrived at conflicting results. This
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9b69e37332e3d5ff2615dc89cf63f16
https://pubmed.ncbi.nlm.nih.gov/22913763
https://pubmed.ncbi.nlm.nih.gov/22913763
Autor:
Heikki Järvinen, Päivi Peltomäki, Annette Gylling, Jukka-Pekka Mecklin, Marjukka Friman, Johanna E. Lotsari, Markku Aarnio, Teijo Kuopio, Wael M. Abdel-Rahman
Publikováno v:
Cancer Research. 72:5018-5018
Breast carcinoma is the most common cancer type in females, but its incidence is generally not increased in Lynch syndrome (LS). Deficient DNA mismatch repair (MMR) is a hallmark of LS tumors that are unequivocal manifestations of the syndrome (e.g.,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a0819c48d1640ef04d0b7f49a45af66a
https://doi.org/10.1158/1538-7445.am2012-5018
https://doi.org/10.1158/1538-7445.am2012-5018
Autor:
Johanna E. Lotsari, Päivi Peltomäki, Sam Al-Sohaily, Sippy Kaur, Maija R.J. Kohonen-Corish, Janindra Warusavitarne
Publikováno v:
Clinical Epigenetics
Background Altered expression of microRNAs (miRNAs) commonly accompanies colorectal (CRC) and endometrial carcinoma (EC) development, but the underlying mechanisms and clinicopathological correlations remain to be clarified. We focused on epigenetic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c64e8d6fbc0d1668ea496a5a4cc759b9