Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Johanna D. James"'
Autor:
Priyanka P. Desai, Kalyani Narra, Johanna D. James, Harlan P. Jones, Amit K. Tripathi, Jamboor K. Vishwanatha
Publikováno v:
Cancers; Volume 15; Issue 1; Pages: 212
Small extracellular vesicles (sEVs), mainly exosomes, are nanovesicles that shed from the membrane as intraluminal vesicles of the multivesicular bodies, serve as vehicles that carry cargo influential in modulating the tumor microenvironment for the
Autor:
Ichiro Nakano, Daniel P. Cahill, Kaushal Joshi, Nina Lelic, Faith Hollingsworth, Hendrikus Boddeke, Adriana Olar, Christopher E. Pelloski, Joy Gumin, Frederick F. Lang, Wilfred F. A. den Dunnen, Se Hoon Kim, Erik P. Sulman, Heidi S. Phillips, Howard Colman, Lihong Long, Khalida Wani, Ganesh Rao, Brian Vaillant, Johanna D. James, Suzhen Wang, Siobhan Conroy, Ravesanker Ezhilarasan, Aditya Raghunathan, Karlijn Hummelink, Lindsey Heathcock, Yoshinori Kodama, Krishna P.L. Bhat, Lindsey D. Goodman, Divya Raj, Amy B. Heimberger, Veerakumar Balasubramaniyan, Kenneth Aldape
Publikováno v:
Cancer cell, 24(3), 331-346. CELL PRESS
Despite extensive study, few therapeutic targets have been identified for glioblastoma (GBM). Here we show that patient-derived glioma sphere cultures (GSCs) that resemble either the proneural (PN) or nnesenchymal (MES) transcriptomal subtypes differ
Autor:
Johanna D. James, Erik P. Sulman, Frederick F. Lang, Tiffany Doucette, Alice Turski, Brian Vaillant, Se Hoon Kim, Katrina Salazar, Howard Colman, Veerakumar Balasubramaniyan, Lindsey Heathcock, Ganesh Rao, Yuhui Yang, Kristin Diefes, Sjef Copray, Krishna P.L. Bhat, Kenneth Aldape, Khalida Wani, Yasaman Azodi, Faith Hollingsworth, Joy Gumin
Publikováno v:
Genes & Development, 25(24), 2594-2609. COLD SPRING HARBOR LAB PRESS, PUBLICATIONS DEPT
Recent molecular classification of glioblastoma (GBM) has shown that patients with a mesenchymal (MES) gene expression signature exhibit poor overall survival and treatment resistance. Using regulatory network analysis of available expression microar
Autor:
Howard Colman, Veerakumar Balasubramainyan, Ravesanker Ezhilarasan, Faith Hollingsworth, Erik P. Sulman, Kenneth Aldape, Brian Vaillant, Lindsey D. Goodman, Krishna P.L. Bhat, Kahlida Wani, Johanna D. James
Publikováno v:
Cancer Research. 72:3314-3314
Here we report the identification of two major subtypes of glioma stem cells (GSCs) that closely mirror previously described glioblastoma (GBM) groups, namely proneural (PN) and mesenchymal (MES), based on gene expression patterns. Using flow cytomet