Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Johanna C. Gandy"'
Autor:
Emma Perez-Costas, Johanna C Gandy, Miguel Melendez-Ferro, Rosalinda C Roberts, Gautam N Bijur
Publikováno v:
PLoS ONE, Vol 5, Iss 1, p e8911 (2010)
Glycogen synthase kinase-3beta (GSK3beta) is highly abundant in the brain. Various biochemical analyses have indicated that GSK3beta is localized to different intracellular compartments within brain cells. However, ultrastructural visualization of th
Externí odkaz:
https://doaj.org/article/99d6d0785a2d4390b6cea18a72776489
Autor:
Johanna C. Gandy, Emma Perez-Costas, Joy K. Roche, Miguel Melendez-Ferro, Benoit Lechat, David Demedts, Rosalinda C. Roberts, Gautam N. Bijur, Fred Van Leuven, Herman Devijver
Publikováno v:
Synapse. 67:313-327
Glycogen synthase kinase-3β (GSK3β) activity has been previously linked to Alzheimer's disease (AD) by its phosphorylation of tau and activation by amyloid. GSK3β intracellular distribution is important in regulating its activity by restricting ac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c6bbfd0c12dfbe03ca0ce4afee669485
https://doi.org/10.1002/syn.21642
https://doi.org/10.1002/syn.21642
Autor:
Rosalinda C. Roberts, Emma Perez-Costas, Johanna C. Gandy, Miguel Melendez-Ferro, Keri A. Barksdale, Gautam N. Bijur
Publikováno v:
The FASEB Journal. 24:3590-3599
Neuronal function in the brain requires energy in the form of ATP, and mitochondria are canonically associated with ATP production in neurons. The electrochemical gradient, which underlies the mitochondrial transmembrane potential (ΔΨmem), is harne
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::689e2601dc5fe81dd6884ec5c54948f2
https://doi.org/10.1096/fj.09-152108
https://doi.org/10.1096/fj.09-152108
Publikováno v:
FEBS Letters. 580:3051-3058
The Ser/Thr kinase Akt1 is activated by growth factors subsequent to its phosphorylation on Thr308 and Ser473. In the present study, Akt1 was found to be constitutively modified with O-GlcNAc. Treatment of SH-SY5Y cells with O(2-acetamido-2-deoxy-d-g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c669f1fd7ac50cd8cb8c1978753f799
https://doi.org/10.1016/j.febslet.2006.04.051
https://doi.org/10.1016/j.febslet.2006.04.051
Autor:
Johanna C, Gandy, Miguel, Melendez-Ferro, Gautam N, Bijur, Fred, Van Leuven, Joy K, Roche, Benoit, Lechat, Herman, Devijver, David, Demedts, Emma, Perez-Costas, Rosalinda C, Roberts
Publikováno v:
Synapse (New York, N.Y.). 67(6)
Glycogen synthase kinase-3β (GSK3β) activity has been previously linked to Alzheimer's disease (AD) by its phosphorylation of tau and activation by amyloid. GSK3β intracellular distribution is important in regulating its activity by restricting ac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::515f946ea795ee4e31f5c109eb907a58
https://pubmed.ncbi.nlm.nih.gov/23390016
https://pubmed.ncbi.nlm.nih.gov/23390016
The ubiquitously expressed protein glycogen synthase kinase-3 (GSK3) is constitutively active, however its activity is markedly diminished following phosphorylation of Ser21 of GSK3alpha and Ser9 of GSK3beta. Although several kinases are known to pho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6e1e79efb806464249ceec11bdbf9c7
https://europepmc.org/articles/PMC1885546/
https://europepmc.org/articles/PMC1885546/
Autor:
Johanna C. Gandy, Emma Perez-Costas, Rosalinda C. Roberts, Gautam N. Bijur, Miguel Melendez-Ferro
Publikováno v:
PLoS ONE
PLoS ONE, Vol 5, Iss 1, p e8911 (2010)
PLoS ONE, Vol 5, Iss 1, p e8911 (2010)
Glycogen synthase kinase-3beta (GSK3beta) is highly abundant in the brain. Various biochemical analyses have indicated that GSK3beta is localized to different intracellular compartments within brain cells. However, ultrastructural visualization of th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87ef1b2b85e1d71361254c438a74e930
https://doi.org/10.1371/journal.pone.0008911
https://doi.org/10.1371/journal.pone.0008911