Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Johanna C. Cool"'
Methotrexate chemotherapy reduces osteogenesis but increases adipogenic potential in the bone marrow
Autor:
Michaela Scherer, Kristen Georgiou, Johanna C. Cool, Tristan J. King, Chiaming Fan, Cory J. Xian, Bruce K. Foster
Publikováno v:
Journal of Cellular Physiology. 227:909-918
Intensive use of cancer chemotherapy is increasingly linked with long-term skeletal side effects such as osteopenia, osteoporosis and fractures. However, cellular mechanisms by which chemotherapy affects bone integrity remain unclear. Methotrexate (M
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e82673ac412583a95045cc312e093f83
https://doi.org/10.1002/jcp.22807
https://doi.org/10.1002/jcp.22807
Autor:
Tetyana Shandala, Chiaming Fan, Cory J. Xian, Bruce K. Foster, Johanna C. Cool, Michaela Scherer, Heather Tapp
Publikováno v:
Bone. 44:61-70
Methotrexate (MTX) is a most commonly used anti-metabolite in cancer treatment and as an anti-rheumatic drug. While MTX chemotherapy at a high dose is known to cause bone growth defects in growing bones, effects of its chronic use at a low dose on gr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c72499dc9050576d633fe858409c155a
https://doi.org/10.1016/j.bone.2008.09.014
https://doi.org/10.1016/j.bone.2008.09.014
Autor:
Pam Roberts, I. Caroline McMillen, Kellie Madigan, Jeffrey S. Robinson, Julie A. Owens, Jill Lipsett, Johanna C. Cool, S. I. C. Runciman, Michelle Tamblyn
Publikováno v:
Pediatric Pulmonology. 41:1138-1145
Intrauterine growth restriction (IUGR) in humans increases the risk of lung disease and impaired function suggesting that adverse intra-uterine conditions can alter lung development. We hypothesized that placental restriction (PR) of fetal growth wou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2315611b14fb96896b25a0d02a7a0220
https://doi.org/10.1002/ppul.20480
https://doi.org/10.1002/ppul.20480
Autor:
Mark S. Geier, Ross N. Butler, Gordon S. Howarth, Jodie L. Dyer, Johanna C. Cool, Cory J. Xian
Publikováno v:
Growth Hormone & IGF Research. 15:72-82
Insulin-like growth factor-I (IGF-I) has been demonstrated to enhance mucosal repair following intestinal damage induced by chemotherapeutic agents (intestinal mucositis). However, the potential for prophylactic IGF-I to protect the intestine remains
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::caa184bbc7b7df9b4c13a748a2d7b96a
https://doi.org/10.1016/j.ghir.2004.12.002
https://doi.org/10.1016/j.ghir.2004.12.002
Autor:
W.D. Andrew Ford, Susan C. Runciman, A. James Martin, Johanna C. Cool, Jill Lipsett, David Parsons, J. Declan Kennedy
Publikováno v:
Pediatric Pulmonology. 30:228-240
The incidence of congenital diaphragmatic hernia (CDH) is 1:1,200-5, 000, and the condition is associated with high mortality and morbidity attributed principally to associated pulmonary hypoplasia. One treatment approach has been for intrauterine in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::513f7087a0bd853780d3407ffb3b044d
https://doi.org/10.1002/1099-0496(200009)30:3<228::aid-ppul7>3.0.co
https://doi.org/10.1002/1099-0496(200009)30:3<228::aid-ppul7>3.0.co
Autor:
C. E. Mardell, Mary Familari, Cory J. Xian, Leanna C. Read, Johanna C. Cool, Andrew S. Giraud, Gordon S. Howarth
Publikováno v:
Europe PubMed Central
Trefoil factor TFF3 has been implicated in intestinal protection and repair. This study investigated the spatiotemporal relationship between TFF3 expression and morphological changes during intestinal damage and repair in a rat model of methotrexate-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a61e6cfbeed5814b2636f81638a6457f
https://doi.org/10.1152/ajpgi.1999.277.4.g785
https://doi.org/10.1152/ajpgi.1999.277.4.g785
Autor:
W.D. Andrew Ford, Johanna C. Cool, Jill Lipsett, S. I. C. Runciman, J. Declan Kennedy, A. James Martin
Publikováno v:
Pediatric Pulmonology. 25:257-269
The incidence of congenital diaphragmatic hernia (CDH) is 1:1,207–5,000, and the condition is associated with high mortality and morbidity, attributed principally to associated pulmonary hypoplasia. Repairing the diaphragmatic defect by antenatal s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::acdc419d767b4a96322497ff591b6773
https://doi.org/10.1002/(sici)1099-0496(199804)25:4<257::aid-ppul6>3.0.co
https://doi.org/10.1002/(sici)1099-0496(199804)25:4<257::aid-ppul6>3.0.co
Publikováno v:
Growth Factors. 15:279-292
We tested the ability of insulin-like growth factor-I (IGF-I) to reduce damage to the intestinal mucosa (mucositis) in rats injected with methotrexate. IGF-I was infused concurrent with methotrexate administration and compared to IGF-I administered f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3b18f4bac1a3f7f2ec85fbcf8b88578
https://doi.org/10.3109/08977199809017483
https://doi.org/10.3109/08977199809017483
Autor:
Jill Lipsett, S. C. Runciman, A. J. Martin, J. D. Kennedy, W. D. A. Ford, Roger W. Byard, Johanna C. Cool
Publikováno v:
Fetal and Pediatric Pathology. 17:789-807
Congenital diaphragmatic hernia (CDH) in humans is relatively common and associated with high mortality attributed mainly to pulmonary hypoplasia. Previous animal models have induced CDH late in gestation, in contrast to the human situation, and only
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64c819dde0f40d26af71fb9cb6645f54
https://doi.org/10.3109/15513819709168601
https://doi.org/10.3109/15513819709168601
Autor:
A. J. Slater, A. J. Martin, W. D. A. Ford, Johanna C. Cool, David Parsons, Jill Lipsett, J. D. Kennedy, Roger W. Byard
Publikováno v:
Pediatric surgery international. 11(8)
Fetal lambs with diaphragmatic herniae (CDH) created surgically at 73 days' gestation were subjected to three different forms of intrauterine correction: silastic patch correction of the diaphragmatic defect plus an abdominal patch at 101 days gestat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f9c4dfb198c917e5536a4afe869f111
https://pubmed.ncbi.nlm.nih.gov/24057840
https://pubmed.ncbi.nlm.nih.gov/24057840