Diagnostic test strategies in children at increased risk of inflammatory bowel disease in primary care.

Autor: Gea A Holtman, Yvonne Lisman-van Leeuwen, Boudewijn J Kollen, Obbe F Norbruis, Johanna C Escher, Laurence C Walhout, Angelika Kindermann, Yolanda B de Rijke, Patrick F van Rheenen, Marjolein Y Berger

Publikováno v: PLoS ONE, Vol 12, Iss 12, p e0189111 (2017)

In children with symptoms suggestive of inflammatory bowel disease (IBD) who present in primary care, the optimal test strategy for identifying those who require specialist care is unclear. We evaluated the following three test strategies to determin

Externí odkaz: https://doaj.org/article/2377926088bf47be9e29961f4eae520f

Changes in natural Foxp3(+)Treg but not mucosally-imprinted CD62L(neg)CD38(+)Foxp3(+)Treg in the circulation of celiac disease patients.

Autor: Marieke A van Leeuwen, M Fleur du Pré, Roy L van Wanrooij, Lilian F de Ruiter, H Rolien C Raatgeep, Dicky J Lindenbergh-Kortleve, Chris J Mulder, Lissy de Ridder, Johanna C Escher, Janneke N Samsom

Publikováno v: PLoS ONE, Vol 8, Iss 7, p e68432 (2013)

BACKGROUND: Celiac disease (CD) is an intestinal inflammation driven by gluten-reactive CD4(+) T cells. Due to lack of selective markers it has not been determined whether defects in inducible regulatory T cell (Treg) differentiation are associated w

Externí odkaz: https://doaj.org/article/262ed0b6d37a4f688fa9507069969150

Prediction of thiopurine failure in pediatric Crohn's disease

Autor: Tereza Lerchova, Ondrej Hradsky, Michal Kulich, Gabor Veres, Jorge Amil Dias, Małgorzata Sładek, Sanja Kolacek, Stephanie Van Biervliet, Jan Melek, Daniela E. Serban, Katrine Winther, Tim de Meij, Jan Schwarz, Kaija-Leena Kolho, Johanna C. Escher, Jiri Bronsky

Publikováno v: Lerchova, T, Hradsky, O, Kulich, M, Veres, G, Dias, J A, Sładek, M, Kolacek, S, van Biervliet, S, Melek, J, Serban, D E, Winther, K, de Meij, T, Schwarz, J, Kolho, K-L, Escher, J C & Bronsky, J 2022, ' Prediction of thiopurine failure in pediatric Crohn’s disease : pediatric IBD Porto group of ESPGHAN ', Pediatric Research . https://doi.org/10.1038/s41390-022-02270-x
Pediatric Research, 93(6), 1659-1666. Lippincott Williams & Wilkins
Pediatric Research. Lippincott Williams and Wilkins

Background Maintaining of remission early in the disease course of Crohn's disease (CD) is essential and has major impact on the future prognosis. This study aimed to identify baseline predictors to develop model allowing stratification of patients w

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f1b80761801f5942637cdf2afbceacb
https://doi.org/10.1038/s41390-022-02270-x

First-line treatment with infliximab versus conventional treatment in children with newly diagnosed moderate-to-severe Crohn's disease

Autor: Michail Doukas, Merel van Pieterson, Sarah T A Teklenburg-Roord, Herbert M. van Wering, Lissy de Ridder, Dimitris Rizopoulos, Martinus A. Cozijnsen, Maria M E Jongsma, Obbe F. Norbruis, Michiel P. van Wijk, Marco W.J. Schreurs, Thalia Hummel, Johanna C. Escher, Janneke M. Stapelbroek, Michael Groeneweg, Kaija-Leena Kolho, Cathelijne van der Feen, Iva Hojsak, Tim G. J. de Meij, Janneke N. Samsom, M Aardoom, Victorien M. Wolters, Patrick F. van Rheenen

Publikováno v: Jongsma, M M E, Aardoom, M A, Cozijnsen, M A, van Pieterson, M, de Meij, T, Groeneweg, M, Norbruis, O F, Wolters, V M, van Wering, H M, Hojsak, I, Kolho, K-L, Hummel, T, Stapelbroek, J, van der Feen, C, van Rheenen, P F, van Wijk, M P, Teklenburg-Roord, S T A, Schreurs, M W J, Rizopoulos, D, Doukas, M, Escher, J C, Samsom, J N & de Ridder, L 2022, ' First-line treatment with infliximab versus conventional treatment in children with newly diagnosed moderate-to-severe Crohn's disease: An open-label multicentre randomised controlled trial ', Gut, vol. 71, no. 1, pp. 34-42 . https://doi.org/10.1136/gutjnl-2020-322339
Gut, 71(1), 34-42. BMJ Publishing Group
Gut, 71, 34-42. BMJ PUBLISHING GROUP

ObjectiveIn newly diagnosed paediatric patients with moderate-to-severe Crohn’s disease (CD), infliximab (IFX) is initiated once exclusive enteral nutrition (EEN), corticosteroid and immunomodulator therapies have failed. We aimed to investigate wh

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93914d348c2a22b66f695b3bebbf019e
https://doi.org/10.1136/gutjnl-2020-322339

Rotterdam Transition Test: A Valid Tool for Monitoring Disease Knowledge in Adolescents With Inflammatory Bowel Disease

Autor: Johanna C. Escher, Lissy de Ridder, Dimitris Rizopoulos, Martha A.C. van Gaalen, Merel van Pieterson, C. Janneke van der Woude, Gertrude van den Brink

Publikováno v: Journal of Pediatric Gastroenterology and Nutrition, 74(1), 60-67. Lippincott Williams & Wilkins

OBJECTIVES Disease knowledge is important in adolescents with inflammatory bowel disease (IBD) transitioning to adult care. We developed an IBD-specific knowledge questionnaire, the Rotterdam Transition Test (RTT), and aimed to validate this tool. ME

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d347028433c3d566c26dccf3e419760b
https://doi.org/10.1097/mpg.0000000000003278