Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Johanna, Mirsch"'
Autor:
Caine Lucas Grandt, Lara Kim Brackmann, Ronja Foraita, Heike Schwarz, Willempje Hummel-Bartenschlager, Thomas Hankeln, Christiane Kraemer, Sebastian Zahnreich, Philipp Drees, Johanna Mirsch, Claudia Spix, Maria Blettner, Heinz Schmidberger, Harald Binder, Moritz Hess, Danuta Galetzka, Federico Marini, Alicia Poplawski, Manuela Marron
Publikováno v:
Molecular Medicine, Vol 29, Iss 1, Pp 1-16 (2023)
Abstract Background Differential expression analysis is usually adjusted for variation. However, most studies that examined the expression variability (EV) have used computations affected by low expression levels and did not examine healthy tissue. T
Externí odkaz:
https://doaj.org/article/9410f81dd4b5435a8409f30524056174
Autor:
Caine Lucas Grandt, Lara Kim Brackmann, Alicia Poplawski, Heike Schwarz, Willempje Hummel-Bartenschlager, Thomas Hankeln, Christiane Kraemer, Federico Marini, Sebastian Zahnreich, Iris Schmitt, Philipp Drees, Johanna Mirsch, Desiree Grabow, Heinz Schmidberger, Harald Binder, Moritz Hess, Danuta Galetzka, Manuela Marron
Publikováno v:
Molecular Medicine, Vol 28, Iss 1, Pp 1-19 (2022)
Abstract Background The etiology and most risk factors for a sporadic first primary neoplasm in childhood or subsequent second primary neoplasms are still unknown. One established causal factor for therapy-associated second primary neoplasms is the e
Externí odkaz:
https://doaj.org/article/5d3e470048f04956814d2b713707f8a8
Autor:
Caine Lucas Grandt, Lara Kim Brackmann, Alicia Poplawski, Heike Schwarz, Federico Marini, Thomas Hankeln, Danuta Galetzka, Sebastian Zahnreich, Johanna Mirsch, Claudia Spix, Maria Blettner, Heinz Schmidberger, Manuela Marron
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
IntroductionLong non-coding ribonucleic acids (lncRNAs) are involved in the cellular damage response following exposure to ionizing radiation as applied in radiotherapy. However, the role of lncRNAs in radiation response concerning intrinsic suscepti
Externí odkaz:
https://doaj.org/article/b0bdc83a02bf48d1aef2fa53dae0bee1
Autor:
Danuta Galetzka, Julia Böck, Lukas Wagner, Marcus Dittrich, Olesja Sinizyn, Marco Ludwig, Heidi Rossmann, Claudia Spix, Markus Radsak, Peter Scholz-Kreisel, Johanna Mirsch, Matthias Linke, Walburgis Brenner, Manuela Marron, Alicia Poplawski, Thomas Haaf, Heinz Schmidberger, Dirk Prawitt
Publikováno v:
EXCLI Journal : Experimental and Clinical Sciences, Vol 21, Pp 117-143 (2022)
Most childhood cancers occur sporadically and cannot be explained by an inherited mutation or an unhealthy lifestyle. However, risk factors might trigger the oncogenic transformation of cells. Among other regulatory signals, hypermethylation of RAD9A
Externí odkaz:
https://doaj.org/article/4a24ce34995f4364bc5fbdf365f6bd5d
Autor:
Lara Kim Brackmann, Alicia Poplawski, Caine Lucas Grandt, Heike Schwarz, Thomas Hankeln, Steffen Rapp, Sebastian Zahnreich, Danuta Galetzka, Iris Schmitt, Christian Grad, Lukas Eckhard, Johanna Mirsch, Maria Blettner, Peter Scholz-Kreisel, Moritz Hess, Harald Binder, Heinz Schmidberger, Manuela Marron
Publikováno v:
Molecular Medicine, Vol 26, Iss 1, Pp 1-13 (2020)
Abstract Background Exposure to ionizing radiation induces complex stress responses in cells, which can lead to adverse health effects such as cancer. Although a variety of studies investigated gene expression and affected pathways in human fibroblas
Externí odkaz:
https://doaj.org/article/877f92056fa24415a22d7f7ef87fe7d6
Autor:
Manuela Marron, Lara Kim Brackmann, Heike Schwarz, Willempje Hummel-Bartenschlager, Sebastian Zahnreich, Danuta Galetzka, Iris Schmitt, Christian Grad, Philipp Drees, Johannes Hopf, Johanna Mirsch, Peter Scholz-Kreisel, Peter Kaatsch, Alicia Poplawski, Moritz Hess, Harald Binder, Thomas Hankeln, Maria Blettner, Heinz Schmidberger
Publikováno v:
JMIR Research Protocols, Vol 10, Iss 11, p e32395 (2021)
BackgroundTherapy for a first primary neoplasm (FPN) in childhood with high doses of ionizing radiation is an established risk factor for second primary neoplasms (SPN). An association between exposure to low doses and childhood cancer is also sugges
Externí odkaz:
https://doaj.org/article/f53c152fb68c4b8c8bbc7f6ec6272c9a
Autor:
Sebastian Zahnreich, Alicia Poplawski, Carola Hartel, Lukas Stefan Eckhard, Danuta Galetzka, Thomas Hankeln, Markus Löbrich, Manuela Marron, Johanna Mirsch, Sylvia Ritter, Peter Scholz-Kreisel, Claudia Spix, Heinz Schmidberger
Publikováno v:
Frontiers in Oncology, Vol 10 (2020)
The purpose of the present study was to investigate whether former childhood cancer patients who developed a subsequent secondary primary neoplasm (SPN) are characterized by elevated spontaneous chromosomal instability or cellular and chromosomal rad
Externí odkaz:
https://doaj.org/article/b5624724e6504bdd994eb7dff60a12a0
Autor:
Caine Lucas Grandt, Lara Kim Brackmann, Ronja Foraita, Heike Schwarz, Willempje Hummel Bartenschlager, Thomas Hankeln, Christiane Kraemer, Sebastian Zahnreich, Philipp Drees, Johanna Mirsch, Claudia Spix, Maria Blettner, Heinz Schmidberger, Harald Binder, Moritz Hess, Danuta Galetzka, Federico Marini, Alicia Poplawski, Manuela Marron
Background: Differential expression analysis is usually adjusted for variation. However, most studies that examined the expression variability (EV) have used computations affected by low expression levels and did not examine healthy tissue. This stud
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::af75bb35756f6b9db6ce422006116051
https://doi.org/10.21203/rs.3.rs-2116997/v1
https://doi.org/10.21203/rs.3.rs-2116997/v1
Autor:
Sebastian Zahnreich, Kamran Yusifli, Alicia Poplawski, Lukas Stefan Eckhard, Johanna Mirsch, Thomas Hankeln, Danuta Galetzka, Manuela Marron, Peter Scholz-Kreisel, Claudia Spix, Heinz Schmidberger
Publikováno v:
DNA repair. 122
New development and optimization of oncologic strategies are steadily increasing the number of long-term cancer survivors being at risk of developing second primary neoplasms (SPNs) as a late consequence of genotoxic cancer therapies with the highest
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5f294302d4783789b7f2278831affd5
https://pubmed.ncbi.nlm.nih.gov/36549044
https://pubmed.ncbi.nlm.nih.gov/36549044
Autor:
Danuta, Galetzka, Julia, Böck, Lukas, Wagner, Marcus, Dittrich, Olesja, Sinizyn, Marco, Ludwig, Heidi, Rossmann, Claudia, Spix, Markus, Radsak, Peter, Scholz-Kreisel, Johanna, Mirsch, Matthias, Linke, Walburgis, Brenner, Manuela, Marron, Alicia, Poplawski, Thomas, Haaf, Heinz, Schmidberger, Dirk, Prawitt
Publikováno v:
EXCLI journal. 21
Most childhood cancers occur sporadically and cannot be explained by an inherited mutation or an unhealthy lifestyle. However, risk factors might trigger the oncogenic transformation of cells. Among other regulatory signals, hypermethylation of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::57b0cc762fa1829d30c1a15a38a00602
https://pubmed.ncbi.nlm.nih.gov/35221838
https://pubmed.ncbi.nlm.nih.gov/35221838