Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Johann du, Hoffmann"'
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Cognitive flexibility, the ability to adapt to unexpected changes, is critical for healthy environmental and social interactions, and thus to everyday functioning. In neuropsychiatric diseases, cognitive flexibility is often impaired and treatment op
Externí odkaz:
https://doaj.org/article/0752ae49210744ecb8f225c342785b4c
Publikováno v:
Nature Neuroscience. 24:1429-1440
The appropriate selection of passive and active defensive behaviors in threatening situations is essential for survival. Previous studies have shown that passive defensive responses depend on activity of the central nucleus of the amygdala (CeA), whe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ffac36263934cf606e3bc4c75f3c0f83
https://doi.org/10.1038/s41593-021-00912-7
https://doi.org/10.1038/s41593-021-00912-7
Autor:
Hala Harony-Nicolas, Maya Kay, Johann du Hoffmann, Matthew E Klein, Ozlem Bozdagi-Gunal, Mohammed Riad, Nikolaos P Daskalakis, Sankalp Sonar, Pablo E Castillo, Patrick R Hof, Matthew L Shapiro, Mark G Baxter, Shlomo Wagner, Joseph D Buxbaum
Publikováno v:
eLife, Vol 6 (2017)
Mutations in the synaptic gene SHANK3 lead to a neurodevelopmental disorder known as Phelan-McDermid syndrome (PMS). PMS is a relatively common monogenic and highly penetrant cause of autism spectrum disorder (ASD) and intellectual disability (ID), a
Externí odkaz:
https://doaj.org/article/15f3de3779bb415499c0098f7ef83e2d
Autor:
Saleem M. Nicola, Johann du Hoffmann
Publikováno v:
Frontiers in Behavioral Neuroscience, Vol 10 (2016)
Dopamine receptor activation in the nucleus accumbens (NAc) promotes vigorous environmentally-cued food-seeking in hungry rats. Rats fed ad libitum, however, respond to fewer food-predictive cues, particularly when the value of food reward is low. He
Externí odkaz:
https://doaj.org/article/40b1f8ed1442420284cd8c180318bc71
Autor:
Dennis Drayna, Terra D. Barnes, Jessica Root, Tae-Un Han, Wang Sik Lee, Laura D. Reyes, Elizabeth B. Huchinson, Johann du Hoffmann
Publikováno v:
Proceedings of the National Academy of Sciences. 116:17515-17524
Stuttering is a common neurodevelopmental disorder that has been associated with mutations in genes involved in intracellular trafficking. However, the cellular mechanisms leading to stuttering remain unknown. Engineering a mutation in N-acetylglucos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6701d8251f74849f614387c894ff2e8a
https://doi.org/10.1073/pnas.1901480116
https://doi.org/10.1073/pnas.1901480116
Autor:
Robert J. Morell, Takushi Miyoshi, Inna A. Belyantseva, Yoko Nakano, Talah T Wafa, Tracy S. Fitzgerald, Jeeva Munasinghe, Lijin Dong, Carlo Pierpaoli, Kevin D Cravedi, Thomas B. Friedman, Johann du Hoffmann, Botond Banfi, Ya-Xian Wang, Koichi Omori, Risa Tona, Wenqian Chen, Ronald S. Petralia, Matthew F. Starost, Laura D. Reyes, Yogita Chudasama
Publikováno v:
Hum Mol Genet
Epilepsy, deafness, onychodystrophy, osteodystrophy and intellectual disability are associated with a spectrum of mutations of human TBC1D24. The mechanisms underlying TBC1D24-associated disorders and the functions of TBC1D24 are not well understood.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b4420e096733f49279c625f679b8c5e
https://doi.org/10.1093/hmg/ddy445
https://doi.org/10.1093/hmg/ddy445
The appropriate selection of reactive and proactive defensive behaviors amid fearful situations is essential for survival. Studies in both rodents and primates have shown that reactive defensive responses depend on the activity of the central nucleus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b8894cb9c6b32993746b82fdcf833b40
https://doi.org/10.21203/rs.3.rs-322756/v1
https://doi.org/10.21203/rs.3.rs-322756/v1
Autor:
Jun, Ma, Johann, du Hoffmann, Morgan, Kindel, B Sofia, Beas, Yogita, Chudasama, Mario A, Penzo
Publikováno v:
Nature neuroscience. 24(10)
The appropriate selection of passive and active defensive behaviors in threatening situations is essential for survival. Previous studies have shown that passive defensive responses depend on activity of the central nucleus of the amygdala (CeA), whe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::303b33e12d102ce9870c63d13846dd9b
https://pubmed.ncbi.nlm.nih.gov/34413514
https://pubmed.ncbi.nlm.nih.gov/34413514
Publikováno v:
Journal of Neurophysiology. 118:2549-2567
The nucleus accumbens (NAc) has often been described as a “limbic-motor interface,” implying that the NAc integrates the value of expected rewards with the motor planning required to obtain them. However, there is little direct evidence that the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1dc75958caeb2dc2e0439c7495f7d493
https://doi.org/10.1152/jn.00465.2017
https://doi.org/10.1152/jn.00465.2017
Autor:
Tae-Un, Han, Jessica, Root, Laura D, Reyes, Elizabeth B, Huchinson, Johann du, Hoffmann, Wang-Sik, Lee, Terra D, Barnes, Dennis, Drayna
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 116(35)
Stuttering is a common neurodevelopmental disorder that has been associated with mutations in genes involved in intracellular trafficking. However, the cellular mechanisms leading to stuttering remain unknown. Engineering a mutation in N-acetylglucos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c36f8df101894b3039bcc421939204b1
https://pubmed.ncbi.nlm.nih.gov/31405983
https://pubmed.ncbi.nlm.nih.gov/31405983