Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Johann Urschitz"'
Autor:
Ashelley Kettyllem Alves de Sousa, Keyla Silva Nobre Pires, Isadora Hart Cavalcante, Iasmin Cristina Lira Cavalcante, Julia Domingues Santos, Maiara Ingrid Cavalcante Queiroz, Ana Catarina Rezende Leite, Alessandre Carmo Crispim, Edmilson Rodrigues da Rocha Junior, Thiago Mendonça Aquino, Rodrigo Barbano Weingrill, Johann Urschitz, Stephanie Ospina-Prieto, Alexandre Urban Borbely
Publikováno v:
Frontiers in Endocrinology, Vol 15 (2024)
IntroductionMicroplastics (MPs) are environmental pollutants that pose potential risks to living organisms. MPs have been shown to accumulate in human organs, including the placenta. In this study, we investigated the biochemical impact of 5 μm poly
Externí odkaz:
https://doaj.org/article/1bd0b282332e478bbff312c3f2ce6fb8
Autor:
Christian Litton, Paula Benny, Luca Lambertini, Yula Ma, Jonathan Riel, Rodrigo Weingrill, Johann Urschitz, Jia Chen, Men-Jean Lee
Publikováno v:
Toxics, Vol 12, Iss 9, p 659 (2024)
Objective: Bisphenol A and phthalate are known endocrine disruptors and capable of inducing epigenetic changes in the human population. However, their impact on the placenta is less well studied. Our objective was to measure the effect of exposure to
Externí odkaz:
https://doaj.org/article/dff89de69c47498e9f017b8abb537721
Autor:
Rodrigo Barbano Weingrill, Men-Jean Lee, Paula Benny, Jonathan Riel, Kevin Saiki, Jacob Garcia, Lais Farias Azevedo de Magalhaes Oliveira, Eduardo Jorge da Silva Fonseca, Samuel Teixeira de Souza, Flavio de Oliveira Silva D'Amato, Ueslen Rocha Silva, Mariana Lima Dutra, Aldilane Lays Xavier Marques, Alexandre Urban Borbely, Johann Urschitz
Publikováno v:
Environment International, Vol 180, Iss , Pp 108220- (2023)
Microplastics are created for commercial use, are shed from textiles, or result from the breakdown of larger plastic items. Recent reports have shown that microplastics accumulate in human tissues and may have adverse health consequences. Currently,
Externí odkaz:
https://doaj.org/article/47a2be2254d349b28d8b583cbacd31e2
Autor:
Rodrigo Barbano Weingrill, Sandra Luft Paladino, Matheus Leite Ramos Souza, Eduardo Manoel Pereira, Aldilane Lays Xavier Marques, Elaine Cristina Oliveira Silva, Eduardo Jorge da Silva Fonseca, Jeferson Santana Ursulino, Thiago Mendonça Aquino, Estela Bevilacqua, Johann Urschitz, Jean Carl Silva, Alexandre Urban Borbely
Publikováno v:
Frontiers in Physiology, Vol 12 (2021)
Hypertensive disorders of pregnancy are closely associated with prematurity, stillbirth, and maternal morbidity and mortality. The onset of hypertensive disorders of pregnancy (HDP) is generally noticed after the 20th week of gestation, limiting earl
Externí odkaz:
https://doaj.org/article/2a7a2cc0424045679abf68322f2711f1
Autor:
Fang Zeng, Sha Liao, Zhe Kuang, Qingchun Zhu, Hengxi Wei, Junsong Shi, Enqin Zheng, Zheng Xu, Sixiu Huang, Linjun Hong, Ting Gu, Jie Yang, Huaqiang Yang, Gengyuan Cai, Stefan Moisyadi, Johann Urschitz, Zicong Li, Zhenfang Wu
Publikováno v:
Cells, Vol 11, Iss 15, p 2378 (2022)
Farm animal salivary glands hold great potential as efficient bioreactors for production of human therapeutic proteins. Nerve growth factor (NGF) is naturally expressed in animal salivary glands and has been approved for human clinical treatment. Thi
Externí odkaz:
https://doaj.org/article/72c5aa4feca94114ad78c37e2648d6f7
Autor:
Chi Ma, FuKun W. Hoffmann, Michael P. Marciel, Kathleen E. Page, Melodie A. Williams-Aduja, Ellis N.L. Akana, Greg S. Gojanovich, Mariana Gerschenson, Johann Urschitz, Stefan Moisyadi, Vedbar S. Khadka, Sharon Rozovsky, Youping Deng, F. David Horgen, Peter R. Hoffmann
Publikováno v:
Molecular Metabolism, Vol 47, Iss , Pp 101170- (2021)
Objective: T cell activation triggers metabolic reprogramming to meet increased demands for energy and metabolites required for cellular proliferation. Ethanolamine phospholipid synthesis has emerged as a regulator of metabolic shifts in stem cells a
Externí odkaz:
https://doaj.org/article/b5d150d02a4340998f52553c81f6b89c
Autor:
Paula Benny, Hyeong Jun Ahn, Janet Burlingame, Men-Jean Lee, Corrie Miller, John Chen, Johann Urschitz
Publikováno v:
PLoS ONE, Vol 16, Iss 12, p e0261137 (2021)
AimsGenome-wide association studies have shown an increased risk of type-2-diabetes (T2DM) in patients who carry single nucleotide polymorphisms in several genes. We investigated whether the same gene loci confer a risk for gestational diabetes melli
Externí odkaz:
https://doaj.org/article/407019822fd14ae587c7369d7069985e
Autor:
Gregory J. Fredericks, FuKun W. Hoffmann, Robert J. Hondal, Sharon Rozovsky, Johann Urschitz, Peter R. Hoffmann
Publikováno v:
Antioxidants, Vol 7, Iss 1, p 4 (2017)
Selenoprotein K (SELENOK) is a selenocysteine (Sec)-containing protein localized in the endoplasmic reticulum (ER) membrane where it interacts with the DHHC6 (where single letter symbols represent Asp-His-His-Cys amino acids) enzyme to promote protei
Externí odkaz:
https://doaj.org/article/b13ec90a8b6843b28e46bbdf45a5661c
Autor:
Gabriela Edwards-Faret, Filip de Vin, Michal Slezak, Lennart Gollenbeck, Ruçhan Karaman, Yohei Shinmyo, Mykhailo Y. Batiuk, Carmen Menacho Pando, Johann Urschitz, Melvin Y. Rincon, Stefan Moisyadi, Frank Schnütgen, Hiroshi Kawasaki, Dietmar Schmucker, Matthew G. Holt
Publikováno v:
Neuroscience.
Advances in single cell sequencing have enabled the identification of a large number of genes, expressed in many different cell types, and across a variety of model organisms. In particular, the nervous system harbors an immense number of interacting
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5f879821ad1808dd6c5a27d4bda1b65
https://pubmed.ncbi.nlm.nih.gov/36464177
https://pubmed.ncbi.nlm.nih.gov/36464177
Autor:
Frank Urena, Chi Ma, FuKun W. Hoffmann, Lance G.A. Nunes, Johann Urschitz, Stefan Moisyadi, Vedbar S. Khadka, Youping Deng, Peter R. Hoffmann
Publikováno v:
The Journal of biological chemistry. 298(3)
While miRs have been extensively studied in the context of malignancy and tumor progression, their functions in regulating T-cell activation are less clear. In initial studies, we found reduced levels of miR-15a/16 at 3 to 18 h post-T-cell receptor (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86fefaf918554e7caa3fd68e657eab22
https://pubmed.ncbi.nlm.nih.gov/35085550
https://pubmed.ncbi.nlm.nih.gov/35085550