Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Johann Mar, Gudbergsson"'
Autor:
Esben Christensen, Johann Mar Gudbergsson, Thomas Lars Andresen, Andreas Kjaer, Kasper Bendix Johnsen, Serhii Kostrikov, Torben Moos, Meg Duroux
Publikováno v:
Gudbergsson, J M, Christensen, E, Kostrikov, S, Moos, T, Duroux, M, Kjær, A, Johnsen, K B & Andresen, T L 2020, ' Conventional Treatment of Glioblastoma Reveals Persistent CD44+ Subpopulations ', Molecular Neurobiology, vol. 57, no. 9, pp. 3943-3955 . https://doi.org/10.1007/s12035-020-02004-2
Glioblastoma (GBM) is the most frequent and devastating primary tumor of the central nervous system with a median survival of 12 to 15 months after diagnosis. GBM is highly difficult to treat due to its delicate location, inter- and intra-tumoral het
Autor:
Andreas Kjaer, Petra Hamerlik, Casper Hempel, Johann Mar Gudbergsson, Thomas Hartig Braunstein, Thomas Lars Andresen, Frederikke P. Fliedner, Anders Elias Hansen, Elisabeth Anne Adanma Obara, Kasper Bendix Johnsen, Serhii Kostrikov
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-16 (2021)
Kostrikov, S, Johnsen, K B, Braunstein, T H, Gudbergsson, J M, Fliedner, F P, Obara, E A A, Hamerlik, P, Hansen, A E, Kjaer, A, Hempel, C & Andresen, T L 2021, ' Optical tissue clearing and machine learning can precisely characterize extravasation and blood vessel architecture in brain tumors ', Communications Biology, vol. 4, no. 1, 815 . https://doi.org/10.1038/s42003-021-02275-y
Communications Biology
Kostrikov, S, Johnsen, K B, Braunstein, T H, Gudbergsson, J M, Fliedner, F P, Obara, E A A, Hamerlik, P, Hansen, A E, Kjaer, A, Hempel, C & Andresen, T L 2021, ' Optical tissue clearing and machine learning can precisely characterize extravasation and blood vessel architecture in brain tumors ', Communications Biology, vol. 4, no. 1, 815 . https://doi.org/10.1038/s42003-021-02275-y
Communications Biology
Precise methods for quantifying drug accumulation in brain tissue are currently very limited, challenging the development of new therapeutics for brain disorders. Transcardial perfusion is instrumental for removing the intravascular fraction of an in
Publikováno v:
Johnsen, K B, Gudbergsson, J M, Andresen, T L & Simonsen, J B 2019, ' What is the blood concentration of extracellular vesicles? Implications for the use of extracellular vesicles as blood-borne biomarkers of cancer ', B B A-Reviews on Cancer, vol. 1871, no. 1, pp. 109-116 . https://doi.org/10.1016/j.bbcan.2018.11.006
Johnsen, K B, Gudbergsson, J M, Andresen, T L & Simonsen, J B 2019, ' What is the blood concentration of extracellular vesicles? Implications for the use of extracellular vesicles as blood-borne biomarkers of cancer ', BBA Reviews on Cancer, vol. 1871, no. 1, pp. 109-116 . https://doi.org/10.1016/j.bbcan.2018.11.006
Johnsen, K B, Gudbergsson, J M, Andresen, T L & Simonsen, J B 2019, ' What is the blood concentration of extracellular vesicles? Implications for the use of extracellular vesicles as blood-borne biomarkers of cancer ', BBA Reviews on Cancer, vol. 1871, no. 1, pp. 109-116 . https://doi.org/10.1016/j.bbcan.2018.11.006
Circulating biomarkers have a great potential in diagnosing cancer diseases at early stages, where curative treatment is a realistic possibility. In the recent years, using extracellular vesicles (EVs) derived from blood as biomarkers has gained wide
Autor:
Johann Mar Gudbergsson
Publikováno v:
Gudbergsson, J M 2020, ' Extracellular vesicles for targeted drug delivery : triumphs and challenges ', Future Medicinal Chemistry, vol. 12, no. 14, pp. 1285-1287 . https://doi.org/10.4155/fmc-2020-0117
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd9cba15a7eb812f4c8acced3173d00a
https://vbn.aau.dk/da/publications/706093d3-3493-46a0-9ffb-5bfad2fca098
https://vbn.aau.dk/da/publications/706093d3-3493-46a0-9ffb-5bfad2fca098
Autor:
Johann Mar, Gudbergsson, Esben, Christensen, Serhii, Kostrikov, Torben, Moos, Meg, Duroux, Andreas, Kjær, Kasper Bendix, Johnsen, Thomas Lars, Andresen
Publikováno v:
Molecular neurobiology. 57(9)
Glioblastoma (GBM) is the most frequent and devastating primary tumor of the central nervous system with a median survival of 12 to 15 months after diagnosis. GBM is highly difficult to treat due to its delicate location, inter- and intra-tumoral het
Autor:
Torben Moos, Kasper Bendix Johnsen, Johann Mar Gudbergsson, Thomas Lars Andresen, Meg Duroux, Jens B. Simonsen
Publikováno v:
Johnsen, K B, Gudbergsson, J M, Duroux, M, Moos, T, Andresen, T L & Simonsen, J B 2018, ' On the use of liposome controls in studies investigating the clinical potential of extracellular vesicle-based drug delivery systems : A commentary ', Journal of Controlled Release, vol. 269, pp. 10-14 . https://doi.org/10.1016/j.jconrel.2017.11.002
The field of extracellular vesicle (EV)-based drug delivery systems has evolved significantly through the recent years, and numerous studies suggest that these endogenous nanoparticles can function as efficient drug delivery vehicles in a variety of
Publikováno v:
Gudbergsson, J M, Jønsson, K, Simonsen, J B & Johnsen, K B 2019, ' Systematic review of targeted extracellular vesicles for drug delivery : Considerations on methodological and biological heterogeneity ', Journal of Controlled Release, vol. 306, pp. 108-120 . https://doi.org/10.1016/j.jconrel.2019.06.006
The idea of using extracellular vesicles (EVs) for targeted drug delivery was first introduced in 2011 and has since then gained increasing attention as promising new candidates in the field. Targeting EVs to areas of disease can be achieved through
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf1651e32d1a1684bae2d9eea2811d1f
https://vbn.aau.dk/da/publications/a1716a54-bdc8-451a-953f-4f264cbd2941
https://vbn.aau.dk/da/publications/a1716a54-bdc8-451a-953f-4f264cbd2941
Autor:
Meg Duroux, Johann Mar Gudbergsson
Publikováno v:
Gudbergsson, J M & Duroux, M 2020, ' An evaluation of different Cripto-1 antibodies and their variable results ', Journal of Cellular Biochemistry, vol. 121, no. 1, pp. 545-556 . https://doi.org/10.1002/jcb.29293
Cripto-1 is a protein expressed during embryonal development and has been linked to several malignant processes in cancer. Since the discovery of cripto-1 in the late 1980s, it has become a subject of biomarker investigation in several types of cance
Publikováno v:
Gudbergsson, J M & Johnsen, K B 2019, ' Exosomes and autophagy : rekindling the vesicular waste hypothesis ', Journal of Cell Communication and Signaling, vol. 13, no. 4, pp. 443-450 . https://doi.org/10.1007/s12079-019-00524-8
Exosomes were first described as waste carriers implicated in reticulocyte maturation but has during the past decade been associated with many other cellular functions. The biogenesis of exosomes has been extensively studied and several protein machi
Autor:
Bjarne Winther Kristensen, Frederikke P. Fliedner, Anders Elias Hansen, Thomas Lars Andresen, Andreas Kjaer, Kasper Bendix Johnsen, Serhii Kostrikov, Nanna Humle, Christian Brøgger Stolberg, Meg Duroux, Gunna Christiansen, Johann Mar Gudbergsson
Publikováno v:
Gudbergsson, J M, Kostrikov, S, Johnsen, K B, Fliedner, F P, Stolberg, C B, Humle, N, Hansen, A E, Kristensen, B W, Christiansen, G, Kjær, A, Andresen, T L & Duroux, M 2019, ' A tumorsphere model of glioblastoma multiforme with intratumoral heterogeneity for quantitative analysis of cellular migration and drug response ', Experimental Cell Research, vol. 379, no. 1, pp. 73-82 . https://doi.org/10.1016/j.yexcr.2019.03.031
Gudbergsson, J M, Kostrikov, S, Johnsen, K B, Fliedner, F P, Stolberg, C B, Humle, N, Hansen, A E, Kristensen, B W, Christiansen, G, Kjaer, A, Andresen, T L & Duroux, M 2019, ' A tumorsphere model of glioblastoma multiforme with intratumoral heterogeneity for quantitative analysis of cellular migration and drug response ', Experimental Cell Research, vol. 379, no. 1, pp. 73-82 . https://doi.org/10.1016/j.yexcr.2019.03.031
Gudbergsson, J M, Kostrikov, S, Johnsen, K B, Fliedner, F P, Stolberg, C B, Humle, N, Hansen, A E, Kristensen, B W, Christiansen, G, Kjaer, A, Andresen, T L & Duroux, M 2019, ' A tumorsphere model of glioblastoma multiforme with intratumoral heterogeneity for quantitative analysis of cellular migration and drug response ', Experimental Cell Research, vol. 379, no. 1, pp. 73-82 . https://doi.org/10.1016/j.yexcr.2019.03.031
Glioblastoma multiforme (GBM) is the most common and malignant type of primary brain tumor and is characterized by its sudden onset and invasive growth into the brain parenchyma. The invasive tumor cells evade conventional treatments and are thought
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a7eeb8c9c62433c6b213326321ce2f7
https://orbit.dtu.dk/en/publications/27fe9d52-12e5-4d80-962a-865ed667c6d4
https://orbit.dtu.dk/en/publications/27fe9d52-12e5-4d80-962a-865ed667c6d4