The effect of certain N-tritylated phenylalanine conjugates of amino-adenosine-3’,5’-cyclic monophosphate on Moloney murine leukaemia virus reverse transcriptase activity

Autor: Johann M. van Zyl, Mario Ariatti, Arthur O. Hawtrey

Publikováno v: South African Journal of Science, Vol 106, Iss 7/8 (2010)

Moloney murine leukaemia virus (M-MuLV) is a member of the retrovirus family. Its cloned reverse transcriptase (RT), similarly to HIV type 1 reverse transcriptase (HIV-1 RT), exhibits DNA-polymerase and ribonuclease H (RNase H) activities capable of

Externí odkaz: https://doaj.org/article/c2648991229f4534bc051715645521b5

Deposition and transport of linezolid mediated by a synthetic surfactant Synsurf

Autor: Lyné, van Rensburg, Johann M, van Zyl, Johan, Smith

Publikováno v: Drug Design, Development and Therapy

Background Previous studies in our laboratory demonstrated that a synthetic peptide containing lung surfactant enhances the permeability of chemical compounds through bronchial epithelium. The purpose of this study was to test two formulations of Syn

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::f2cb3f1946ee9678709dee71c2c14c59
https://pubmed.ncbi.nlm.nih.gov/29765201

The C2 variant of human serum transferrin retains the iron binding properties of the native protein

Autor: Chiara Gabbiani, Pierluigi Mauri, Silvia Gabrielli, Susan J. van Rensburg, Johann M. van Zyl, Paolo Zatta, Luigi Messori

Publikováno v: Biochimica et biophysica acta. Molecular basis of disease 1741 (2005): 264–270. doi:10.1016/j.bbadis.2005.04.009
info:cnr-pdr/source/autori:Zatta P, Messori L, Mauri P, van Rensburg SJ, van Zyl J, Gabrielli S, Gabbiani C./titolo:The C2 variant of human serum transferrin retains the iron binding properties of the native protein/doi:10.1016%2Fj.bbadis.2005.04.009/rivista:Biochimica et biophysica acta. Molecular basis of disease/anno:2005/pagina_da:264/pagina_a:270/intervallo_pagine:264–270/volume:1741

The tryptic digests of blood samples obtained from transferrin C1 and C2 (TfC1 and TfC2 hereafter) genotypes were analysed by Liquid Chromatography coupled to Electrospray Mass Spectrometry (LC/ESI–MS/MS). The analytical results confirmed the singl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a688ad05015ea084a311208eac79b876

Purification, characterization and biosynthesis of parabutoxin 3, a component ofParabuthus transvaalicusvenom

Autor: Liliane Schoofs, Isabelle Huys, Karin Dyason, Etienne Waelkens, G.J. Muller, Johann M. van Zyl, Jan Tytgat, Elke Clynen, Fons Verdonck, Jurg van der Walt, Johan du Plessis

Publikováno v: European Journal of Biochemistry. 269:1854-1865

A novel peptidyl inhibitor of voltage-gated K+ channels, named parabutoxin 3 (PBTx3), has been purified to homogeneity from the venom of Parabuthus transvaalicus. This scorpion toxin contains 37 residues, has a mass of 4274 Da and displays 41% identi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::15c7cd57a72029ad55169a6276ef2b19
https://doi.org/10.1046/j.1432-1033.2002.02833.x

Anti-oxidant properties of H2-receptor antagonists

Autor: Ben J. van der Walt, André Kriegler, Johann M. van Zyl

Publikováno v: Biochemical Pharmacology. 45:2389-2397

Ulcerogenesis of the gastroduodenal mucosa is caused by the digestive action of gastric juice and initially involves an inflammatory reaction with infiltration of phagocytes. The anti-inflammatory activity of many drugs have been attributed to the in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ddebaaceef7f27084c756055f7352933
https://doi.org/10.1016/0006-2952(93)90218-l