Výsledky vyhledávání - "Johann Le Floc'h"

Tetrazine-Derived Near-Infrared Dye as a Facile Reagent for Developing Targeted Photoacoustic Imaging Agents

Autor: Christine E. M. Demore, Rowan Swann, Zoya Naperstkow, Johann Le Floc'h, Salma Al-Karmi, Kevin Wyszatko, Yohannes Soenjaya, Stuart Foster, Nancy Janzen, Amber Faraday, John F. Valliant, Samantha R. Slikboer

Publikováno v: Molecular pharmaceutics. 17(9)

A new photoacoustic (PA) dye was developed as a simple-to-use reagent for creating targeted PA imaging agents. The lead molecule was prepared via an efficient two-step synthesis from an inexpensive commercially available starting material. With the d

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8da6706f936dff7c7b4e16fe6b51ec39
https://pubmed.ncbi.nlm.nih.gov/32697098

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Transcranial Photoacoustic Detection of Blood-Brain Barrier Disruption Following Focused Ultrasound-Mediated Nanoparticle Delivery

Autor: Johann Le Floc'h, Hoang D. Lu, Kullervo Hynynen, F. Stuart Foster, Robert K. Prud'homme, Christine E. M. Demore, Tristan L. Lim

Publikováno v: Mol Imaging Biol

PURPOSE: Blood-brain barrier disruption (BBBD) is of interest for treating neurodegenerative diseases and tumors by enhancing drug delivery. Focused ultrasound (FUS) is a powerful method to alleviate BBB challenges; however, the detection of BBB open

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ddc58c5f49a35d74d17742dad814ea0f
https://pubmed.ncbi.nlm.nih.gov/31286352

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Notice of Removal: Photoacoustic assessment of nanoparticles distribution pattern in the mouse brain following blood-brain barrier (BBB) disruption

Autor: Christine E. M. Demore, Hoang D. Lu, Kullervo Hynynen, Johann Le Floc'h, F. Stuart Foster, Robert K. Prud'homme

Publikováno v: 2017 IEEE International Ultrasonics Symposium (IUS).

Focused ultrasound (FUS) with circulating microbubbles creates transient and reversible permeabilization of vasculatures which provides an essential means to deliver therapeutics and imaging agents, for instance across the BBB. We have previously sho

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f728ddcf6bc3ebaab8cffa25b7b1088a
https://doi.org/10.1109/ultsym.2017.8091584

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Markers of cochlear inflammation using MRI

Autor: Beau Pontre, Alfred L. Nuttall, Peter R. Thorne, Johann Le Floc'h, R. S. Telang, Srdjan M. Vlajkovic, Winston Tan, William D. Rooney

Publikováno v: Journal of Magnetic Resonance Imaging. 39:150-161

HEARING LOSS FROM injury and disease of the auditory sensory organ, the cochlea, affects a large and increasing proportion of the population (1,2). There is a need to understand the mechanisms of cochlear injury to develop targeted treatments for hea

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9e96cb38be7644a5983258567069b1e8
https://doi.org/10.1002/jmri.24144

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Evaluation of cardiovascular flow characteristics in the 129Sv mouse foetus using color-Doppler-guided spectral Doppler ultrasound

Autor: Paul Barthez, Wilfried Mai, Didier Vray, Johann Le Floc’h, Marc Janier, Jacques Samarut

Publikováno v: Vet Radiol Ultrasound
Vet Radiol Ultrasound, 2004, 45 (6), pp.568\textendash573
HAL
Veterinary Radiology and Ultrasound
Veterinary Radiology and Ultrasound, 2004, 45 (6), pp.568-573
Veterinary Radiology and Ultrasound, Wiley, 2004, 45 (6), pp.568-573

The purpose of this study was to evaluate color- and spectral Doppler ultrasound in the establishment of normal functional cardiovascular development features in the mouse fetus. Mouse fetuses (129Sv strain) were studied in utero between embryonic da

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a52b7285a4761f56c6937fcc489fd85c
https://hal.archives-ouvertes.fr/hal-01985949

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Developmental changes in integrated ultrasound backscatter from embryonic blood in vivo in mice at high US frequency

Autor: Didier Vray, Johann Le Floc’h, F. Stuart Foster, Carol Akirav, Emmanuel Cherin, Ming Y. Zhang, S. Lee Adamson

Publikováno v: Ultrasound in medicinebiology. 30(10)

Mouse blood imaged using high-frequency ultrasound (US) is more echogenic in embryos than in adults. Studying changes in blood echogenicity in embryos may be of fundamental interest in studies on the genetic regulation of normal and abnormal blood de

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d98ff30b273b38f28bfabbf8d3843855
https://pubmed.ncbi.nlm.nih.gov/15582230

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