Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Johann Kurz"'
Autor:
Benedikt Gasser, Genevieve Escher, Anca-Elena Calin, Michael Deppeler, Miriam Marchon, Clarissa Vögel, Johann Kurz, Markus Mohaupt
Publikováno v:
Comprehensive Psychoneuroendocrinology, Vol 16, Iss , Pp 100208- (2023)
Externí odkaz:
https://doaj.org/article/d1aed049148d4d9eb5bd9b8363484191
Autor:
Benedikt Gasser, Genevieve Escher, Anca-Elena Calin, Michael Deppeler, Miriam Marchon, Johann Kurz, Markus Mohaupt
Publikováno v:
Comprehensive Psychoneuroendocrinology, Vol 16, Iss , Pp 100196- (2023)
Background: Different lines of evidence imply that metformin could alter steroid hormone homeostasis and thereby improve social impairment. Here, we tried to correlate the impact of metformin treatment on alterations in steroid hormones and autism sp
Externí odkaz:
https://doaj.org/article/975a7ed27ac14c77bba14a1da0e63ee3
Autor:
Benedikt Gasser, Genevieve Escher, Anca-Elena Calin, Michael Deppeler, Miriam Marchon, Hiten D. Mistry, Johann Kurz, Markus G. Mohaupt
Publikováno v:
Life, Vol 13, Iss 5, p 1094 (2023)
Background: We recently reported that metformin administration has substantial effects on steroid hormone concentrations. In this study, we specifically explored which enzymatic activities were affected before a first treatment versus after a time of
Externí odkaz:
https://doaj.org/article/ea6fc1b42df846899d05c80da21375f6
Publikováno v:
Translational Psychiatry, Vol 11, Iss 1, Pp 1-3 (2021)
Externí odkaz:
https://doaj.org/article/cdbf5fdb5117485eb27f0c742520b43a
Autor:
Benedikt Gasser, Anca-Elena Calin, Genevieve Escher, Johann Kurz, Aglaia Emmenegger, Samuel Buerki, Arno Schmidt-Trucksäss, Markus Mohaupt
Publikováno v:
Life, Vol 12, Iss 11, p 1736 (2022)
Background: Metformin is an effective treatment option for type 2 diabetes mellitus, and it is, to this day, the most prescribed oral antiglycaemic drug. Besides its effects mainly on mitochondrial activity, an off-label use came up as a pharmaceutic
Externí odkaz:
https://doaj.org/article/979f09064f454d89acbfd49b988b165c
Publikováno v:
Life, Vol 12, Iss 7, p 1004 (2022)
Background: Evidence exists that steroid hormones are altered in individuals with autism, especially androgens. Despite lower prevalence in girls than boys, evidence of potential alterations in progesterone metabolites is sparse, so the aim of this s
Externí odkaz:
https://doaj.org/article/16cd5b959ec64b77bd18316ef53844e3
Publikováno v:
Life, Vol 12, Iss 7, p 998 (2022)
Background: Social behavior is mediated by steroid hormones, whereby various lines of evidence indicate that metformin might improve the symptoms of social withdrawal. This directly yields to the aim of the study to correlate the impact of metformin
Externí odkaz:
https://doaj.org/article/c15b2b07bf9e401284959ec6ccff228c
Publikováno v:
Life, Vol 12, Iss 6, p 867 (2022)
Background: Increasing evidence exists that higher levels of androgens can be found in individuals with autism. Evidence yields to a susceptible role of Cytochrome P450 17A1 (CYP17A1) with its catalyzation of the two distinct types of substrate oxida
Externí odkaz:
https://doaj.org/article/8ae6aad3d94b41e59d9ccb60ccc0b204
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 22, p 12324 (2021)
Introduction: There is increasing evidence that steroid hormone levels and, especially, androgen levels are elevated in autism. An overactivity of 17, 20-lyase with a higher production of the testosterone precursors dehydroepiandrosterone (DHEA) and
Externí odkaz:
https://doaj.org/article/bad54115726d40908c124cd0bfd85872
Publikováno v:
Diseases, Vol 9, Iss 1, p 13 (2021)
Background: Epitestosterone [E] has for a long time been considered as a biologically inactive androgen. However, recently a distinct antiandrogenic activity of this naturally occurring endogenous epimer of Testosterone has been demonstrated. Especia
Externí odkaz:
https://doaj.org/article/7b340c97cd554d2baecdbac220542b96