Zobrazeno 1 - 10
of 67
pro vyhledávání: '"Johann K Eberhart"'
Publikováno v:
PLoS Genetics, Vol 17, Iss 5, p e1009579 (2021)
We sought to understand how perturbation of signaling pathways and their targets generates variable phenotypes. In humans, GATA3 associates with highly variable defects, such as HDR syndrome, microsomia and choanal atresia. We previously characterize
Externí odkaz:
https://doaj.org/article/79ec99f43439430aad2022f46f0e2500
Publikováno v:
PLoS Genetics, Vol 13, Iss 12, p e1007112 (2017)
Integrated development of diverse tissues gives rise to a functional, mobile vertebrate musculoskeletal system. However, the genetics and cellular interactions that drive the integration of muscle, tendon, and skeleton are poorly understood. In the v
Externí odkaz:
https://doaj.org/article/8f1be2a3502b4860922583ae37c1ffb7
Publikováno v:
PLoS ONE, Vol 8, Iss 3, p e59533 (2013)
In human, mutation of the transcription factor SATB2 causes severe defects to the palate and jaw. The expression and sequence of SATB2 is highly conserved across vertebrate species, including zebrafish. We sought to understand the regulation of satb2
Externí odkaz:
https://doaj.org/article/79781621334240cabfda61f1a67a5a82
Publikováno v:
Frontiers in Physiology. 14
Forming a vertebrate head involves the meticulous integration of multiple tissue types during development. Prenatal alcohol exposure is known to cause a variety of birth defects, especially to tissues in the vertebrate head. However, a systematic ana
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::be78eb7702100abbf48509f7ffacf09b
https://doi.org/10.3389/fphys.2023.1131075
https://doi.org/10.3389/fphys.2023.1131075
Autor:
Joshua L. Everson, Johann K. Eberhart
Publikováno v:
Current Topics in Developmental Biology ISBN: 9780128201572
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4371fea4720065cbae815aef93ed0b2d
https://doi.org/10.1016/bs.ctdb.2022.10.003
https://doi.org/10.1016/bs.ctdb.2022.10.003
Publikováno v:
Birth defects researchREFERENCES.
Losses and malformations of cranial neural crest cell (cNCC) derivatives are a hallmark of several common brain and face malformations. Nevertheless, the etiology of these cNCC defects remains unknown for many cases, suggesting a complex basis involv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84842ea11277b273921fcae51b30fdfb
https://pubmed.ncbi.nlm.nih.gov/36369674
https://pubmed.ncbi.nlm.nih.gov/36369674
Embryonic Nicotine Exposure Disrupts Adult Social Behavior and Craniofacial Development in Zebrafish
Publikováno v:
Toxics; Volume 10; Issue 10; Pages: 612
Cigarette smoking remains the leading cause of preventable death and morbidity worldwide. Smoking during pregnancy is associated with numerous adverse birth outcomes, including craniofacial and behavioral abnormalities. Although tobacco smoke contain
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0445df091defd2c9db187f32688e3ed2
https://pubmed.ncbi.nlm.nih.gov/36287892
https://pubmed.ncbi.nlm.nih.gov/36287892
Autor:
Sarah LaPotin, Mary E. Swartz, David M. Luecke, Savvas J. Constantinou, Jason R. Gallant, Johann K. Eberhart, Harold H. Zakon
Publikováno v:
Science Advances. 8
South American and African weakly electric fish independently evolved electric organs from muscle. In both groups, a voltage-gated sodium channel gene independently lost expression from muscle and gained it in the electric organ, allowing the channel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f895fe2a2e1f855dbc7c3e2217f6e24
https://doi.org/10.1126/sciadv.abm2970
https://doi.org/10.1126/sciadv.abm2970
Autor:
Elva Ye, Yohaan Fernandes, Kenneth A. Johnson, Timothy P. Kuka, Tyler L. Dangerfield, Bailey S. Bouley, Chinh Q. Ngo, Da Xie, Emily L. Que, Kanchan Aggarwal, Johann K. Eberhart, Mandira Banik, Yan Jessie Zhang, Brenda P. Medellin
Publikováno v:
Journal of the American Chemical Society. 142:14522-14531
Two azobenzenesulfonamide molecules with thermally stable cis configurations resulting from fluorination of positions ortho to the azo group are reported that can differentially regulate the activity of carbonic anhydrase in the trans and cis configu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4056eed794515e290c1e48397bb6e8a8
https://doi.org/10.1021/jacs.0c05383
https://doi.org/10.1021/jacs.0c05383
Autor:
Ranjeet D. Kar, Johann K. Eberhart
Publikováno v:
International Journal of Molecular Sciences; Volume 24; Issue 2; Pages: 1222
Most human birth defects are phenotypically variable even when they share a common genetic basis. Our understanding of the mechanisms of this variation is limited, but they are thought to be due to complex gene-environment interactions. Loss of the t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f873f38d5c1d4be9c502fb0268f9f03b
https://doi.org/10.3390/ijms24021222
https://doi.org/10.3390/ijms24021222