Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Johann Jaud"'
Publikováno v:
PLoS ONE, Vol 4, Iss 2, p e4612 (2009)
The protein family of kinesins contains processive motor proteins that move stepwise along microtubules. This mechanism requires the precise coupling of the catalytic steps in the two heads, and their precise mechanical coordination. Here we show tha
Externí odkaz:
https://doaj.org/article/fb14fd9956254758b08d533c407ce2d4
Publikováno v:
Proceedings of the National Academy of Sciences. 103:8680-8685
Myosin-V is a linear molecular motor that hydrolyzes ATP to move processively toward the plus end of actin filaments. Motion of this motor under low forces has been studied recently in various single-molecule assays. In this paper we show that myosin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cc8c2b475f24acedca719030d3c782a1
https://doi.org/10.1073/pnas.0510191103
https://doi.org/10.1073/pnas.0510191103
Autor:
Michael Bärmann, Mojca Vilfan, Matthias Rief, Junshan Zhang, Anabel E.-M. Clemen, Johann Jaud
Publikováno v:
Biophysical Journal. 88(6):4402-4410
Myosin-V is a processive two-headed actin-based motor protein involved in many intracellular transport processes. A key question for understanding myosin-V function and the communication between its two heads is its behavior under load. Since in vivo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1487c85c2c52f4db5b57d9d3a1b6fe6b
Publikováno v:
PLoS ONE
PLoS ONE, Vol 4, Iss 2, p e4612 (2009)
PLoS ONE, Vol 4, Iss 2, p e4612 (2009)
The protein family of kinesins contains processive motor proteins that move stepwise along microtubules. This mechanism requires the precise coupling of the catalytic steps in the two heads, and their precise mechanical coordination. Here we show tha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f256be2d20c0a499bf9294fe3b9732cb
http://europepmc.org/articles/PMC2644789
http://europepmc.org/articles/PMC2644789
Autor:
Klaudiusz Mann, Agata L. Starosta, Günther Woehlke, Rebecca Schüle, Ludger Schöls, Bettina Ebbing, Johann Jaud
Publikováno v:
Human molecular genetics. 17(9)
Hereditary spastic paraplegia (HSP) is a neurodegenerative disease caused by motoneuron degeneration. It is linked to at least 30 loci, among them SPG10, which causes dominant forms and originates in point mutations in the neuronal Kinesin-1 gene (KI
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb1c5a6d5ead7ffee4a5326e65a13a94
https://pubmed.ncbi.nlm.nih.gov/18203753
https://pubmed.ncbi.nlm.nih.gov/18203753
Publikováno v:
Biophysical Journal. (4):1407-1412
Kinesin-1 is a dimeric motor protein that moves stepwise along microtubules. A two-stranded α-helical coiled-coil formed by the neck domain links the two heads of the molecule, and forces the motor heads to alternate. By exchanging the particularly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f789b1772e0e88e70c4b485e0a04de17