Zobrazeno 1 - 10
of 115
pro vyhledávání: '"Johann, Hitzler"'
Autor:
André Baruchel, Jean-Pierre Bourquin, John Crispino, Sergi Cuartero, Henrik Hasle, Johann Hitzler, Jan-Henning Klusmann, Shai Izraeli, Andrew A. Lane, Sébastien Malinge, Karen R. Rabin, Irene Roberts, Sandra Ryeom, Sarah K. Tasian, Elvin Wagenblast
Publikováno v:
Haematologica, Vol 108, Iss 10 (2023)
Children with Down syndrome (DS, trisomy 21) are at a significantly higher risk of developing acute leukemia compared to the overall population. Many studies investigating the link between trisomy 21 and leukemia initiation and progression have been
Externí odkaz:
https://doaj.org/article/dcd8614ac85d403187af8360be79dab7
Autor:
Ellen van der Plas, T. Leigh Spencer Noakes, Darci T. Butcher, Rosanna Weksberg, Laura Galin-Corini, Elizabeth A. Wanstall, Patrick Te, Laura Hopf, Sharon Guger, Brenda J. Spiegler, Johann Hitzler, Russell J. Schachar, Shinya Ito, Brian J. Nieman
Publikováno v:
NeuroImage: Clinical, Vol 28, Iss , Pp 102428- (2020)
Introduction: Cure rates for pediatric acute lymphoblastic leukemia (ALL) have reached an all-time high (>90%); however, neurocognitive difficulties continue to affect quality of life in at least a subset of survivors. There are relatively few quanti
Externí odkaz:
https://doaj.org/article/c35aaa3954814a38952ea53818eb85ba
The clinical utility of integrative genomics in childhood cancer extends beyond targetable mutations
Autor:
Anita Villani, Scott Davidson, Nisha Kanwar, Winnie W. Lo, Yisu Li, Sarah Cohen-Gogo, Fabio Fuligni, Lisa-Monique Edward, Nicholas Light, Mehdi Layeghifard, Ricardo Harripaul, Larissa Waldman, Bailey Gallinger, Federico Comitani, Ledia Brunga, Reid Hayes, Nathaniel D. Anderson, Arun K. Ramani, Kyoko E. Yuki, Sasha Blay, Brittney Johnstone, Cara Inglese, Rawan Hammad, Catherine Goudie, Andrew Shuen, Jonathan D. Wasserman, Rosemarie E. Venier, Marianne Eliou, Miranda Lorenti, Carol Ann Ryan, Michael Braga, Meagan Gloven-Brown, Jianan Han, Maria Montero, Famida Spatare, James A. Whitlock, Stephen W. Scherer, Kathy Chun, Martin J. Somerville, Cynthia Hawkins, Mohamed Abdelhaleem, Vijay Ramaswamy, Gino R. Somers, Lianna Kyriakopoulou, Johann Hitzler, Mary Shago, Daniel A. Morgenstern, Uri Tabori, Stephen Meyn, Meredith S. Irwin, David Malkin, Adam Shlien
Publikováno v:
Nature Cancer. 4:203-221
We conducted integrative somatic–germline analyses by deeply sequencing 864 cancer-associated genes, complete genomes and transcriptomes for 300 mostly previously treated children and adolescents/young adults with cancer of poor prognosis or with r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8cc564393b318b298215f3cddc8037c8
https://doi.org/10.1038/s43018-022-00474-y
https://doi.org/10.1038/s43018-022-00474-y
Autor:
Johann Hitzler, Elihu Estey
Publikováno v:
Haematologica, Vol 104, Iss 1 (2019)
Externí odkaz:
https://doaj.org/article/a74ec890057a402c8ffc71815ecef259
Autor:
Fan‐Chi Hsu, Chad Hudson, Elisabeth R. Wilson, Laura M. Pardo, Timothy P. Singleton, Dongbin Xu, Barbara K. Zehentner, Johann Hitzler, Jason Berman, Denise A. Wells, Michael R. Loken, Lisa Eidenschink Brodersen
Publikováno v:
Cytometry Part B: Clinical Cytometry.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::055a6b4547fcb5eae4b80e10e4624f12
https://doi.org/10.1002/cyto.b.22118
https://doi.org/10.1002/cyto.b.22118
Autor:
Brian J. Nieman, Ellen van der Plas, Shinya Ito, Johann Hitzler, Russell J. Schachar, Brenda J. Spiegler, Sharon L. Guger, Rosanna Weksberg, Darci T. Butcher, Yu-Qing Zhou, Connor Nicholls, Amanda Forwell, Thomas S. Przybycien, T. Leigh Spencer Noakes
Additional figures and tables
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37a19d13a3ba5ab8cf42558c6a925f9b
https://doi.org/10.1158/1078-0432.22469361.v1
https://doi.org/10.1158/1078-0432.22469361.v1
Autor:
Brian J. Nieman, Ellen van der Plas, Shinya Ito, Johann Hitzler, Russell J. Schachar, Brenda J. Spiegler, Sharon L. Guger, Rosanna Weksberg, Darci T. Butcher, Yu-Qing Zhou, Connor Nicholls, Amanda Forwell, Thomas S. Przybycien, T. Leigh Spencer Noakes
Purpose:Chemotherapy for childhood acute lymphoblastic leukemia (ALL) can cause late-appearing side effects in survivors that affect multiple organs, including the heart and brain. However, the complex ALL treatment regimen makes it difficult to isol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b354573a5c254515d671c25998a9a1b
https://doi.org/10.1158/1078-0432.c.6527235.v1
https://doi.org/10.1158/1078-0432.c.6527235.v1
Autor:
Reuven J. Schore, Anne L. Angiolillo, John A. Kairalla, Meenakshi Devidas, Karen R. Rabin, Patrick Zweidler-McKay, Michael J. Borowitz, Brent Wood, Andrew J. Carroll, Nyla A. Heerema, Mary V. Relling, Johann Hitzler, Nina S. Kadan-Lottick, Kelly Maloney, Cindy Wang, William L. Carroll, Naomi J. Winick, Elizabeth A. Raetz, Mignon L. Loh, Stephen P. Hunger
Publikováno v:
Leukemia.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1ddfa816e82ca18b31e4973ca2be53ae
https://doi.org/10.1038/s41375-023-01870-8
https://doi.org/10.1038/s41375-023-01870-8
Autor:
Federico Comitani, Joshua O. Nash, Sarah Cohen-Gogo, Astra I. Chang, Timmy T. Wen, Anant Maheshwari, Bipasha Goyal, Earvin S. Tio, Kevin Tabatabaei, Chelsea Mayoh, Regis Zhao, Ben Ho, Ledia Brunga, John E. G. Lawrence, Petra Balogh, Adrienne M. Flanagan, Sarah Teichmann, Annie Huang, Vijay Ramaswamy, Johann Hitzler, Jonathan D. Wasserman, Rebecca A. Gladdy, Brendan C. Dickson, Uri Tabori, Mark J. Cowley, Sam Behjati, David Malkin, Anita Villani, Meredith S. Irwin, Adam Shlien
Acknowledgements: The KiCS program is supported by the Garron Family Cancer Centre at The Hospital for Sick Children through funding from the SickKids Foundation. A.H. received funding from the Canadian Institutes for Health Research (grant no. 16226
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ada5b5437ec15ebb28d90ee77a36f51
https://www.repository.cam.ac.uk/handle/1810/347836
https://www.repository.cam.ac.uk/handle/1810/347836
Autor:
R. Spencer Tong, Robert B. Gerbing, Todd A. Alonzo, Jeffrey W. Taub, Jim Wang, Lisa Eidenschink Brodersen, Reuven J. Schore, Maureen M. O'Brien, Amy Heerema-McKenney, Jason N. Berman, Shelton A Viola, Michael R. Loken, E. Anders Kolb, Betsy A. Hirsch, Alan S. Gamis, Karen M. Chisholm, Susana C. Raimondi, Nobuko Hijiya, Amy Beckman, Johann Hitzler, Todd E. Druley
Publikováno v:
Blood. 138:2337-2346
Myeloid leukemia in children with Down syndrome (ML-DS) is associated with young age and somatic GATA1 mutations. Because of high event-free survival (EFS) and hypersensitivity of the leukemic blasts to chemotherapy, the prior Children’s Oncology G
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e09340fb26ba3d69a872971ec1b2e4b9
https://doi.org/10.1182/blood.2021012206
https://doi.org/10.1182/blood.2021012206