Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Johan Zuidema"'
Autor:
Anne-Eva van der Wijk, Theodosia Georgakopoulou, Rob Steendam, Johan Zuidema, Peter L. Hordijk, Erik N.T.P. Bakker, Ed van Bavel
Publikováno v:
Drug Delivery, Vol 30, Iss 1 (2023)
AbstractDrug development for neurological diseases is greatly impeded by the presence of the blood-brain barrier (BBB). We and others previously reported on extravasation of micrometer-sized particles from the cerebral microcirculation – across the
Externí odkaz:
https://doaj.org/article/964217b972054fc4925a86e5830a37c9
Autor:
Renée S. van der Kooij, Martin Beukema, Anke L. W. Huckriede, Johan Zuidema, Rob Steendam, Henderik W. Frijlink, Wouter L. J. Hinrichs
Publikováno v:
Pharmaceutics, Vol 15, Iss 2, p 676 (2023)
Although vaccination is still considered to be the cornerstone of public health care, the increase in vaccination coverage has stagnated for many diseases. Most of these vaccines require two or three doses to be administered across several months or
Externí odkaz:
https://doaj.org/article/27a8c796e4d9408694c042d4ad83969b
Autor:
Renée S. van der Kooij, Rob Steendam, Johan Zuidema, Henderik W. Frijlink, Wouter L. J. Hinrichs
Publikováno v:
Pharmaceutics, Vol 13, Iss 11, p 1854 (2021)
For many vaccines, multiple injections are required to confer protective immunity against targeted pathogens. These injections often consist of a primer administration followed by a booster administration of the vaccine a few weeks or months later. A
Externí odkaz:
https://doaj.org/article/bda5dc6c013847dc8c076d0c0e07e904
Autor:
Klaas Poelstra, Matthias H. M. Klose, Angela Casini, F. van Dijk, Leonie Beljaars, Niels J. Sijbrandi, Samuel M. Meier-Menches, Eduard Post, Peter Olinga, Detlef Schuppan, Yong Ook Kim, Peter Horvatovich, Wouter L. J. Hinrichs, Naomi Teekamp, Johan Zuidema, Rob Steendam, Hendrik W. Frijlink
Publikováno v:
Journal of Controlled Release, 296, 250-257. Elsevier Bedrijfsinformatie b.v.
Rho kinase activity in hepatic stellate cells (HSCs) is associated with activation, transformation and contraction of these cells, leading to extracellular matrix production and portal hypertension in liver cirrhosis. Inhibition of rho kinase activit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e32fbe853d5c3858aa46577f4d6af2e
https://research.rug.nl/en/publications/125e52bd-45b3-47c2-9f0c-0e083c2f927a
https://research.rug.nl/en/publications/125e52bd-45b3-47c2-9f0c-0e083c2f927a
Autor:
Annemarie Broesder, Klaas Poelstra, Peter Olinga, F. van Dijk, Eduard Post, M. Evers, Jan-Luuk Hillebrands, Henderik W. Frijlink, Johan Zuidema, Wouter L. J. Hinrichs, Naomi Teekamp, Rob Steendam, Leonie Beljaars
Publikováno v:
International Journal of Pharmaceutics, 534(1-2), 229-236. Elsevier Bedrijfsinformatie b.v.
Injectable sustained release drug delivery systems are an attractive alternative for the intravenous delivery of therapeutic proteins. In particular, for chronic diseases such as fibrosis, this approach could improve therapy by reducing the administr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f267cbced933153c7a7729638dcd58a8
https://research.rug.nl/en/publications/a60ad7df-0cc8-4b96-b869-bdc9f2ef25d2
https://research.rug.nl/en/publications/a60ad7df-0cc8-4b96-b869-bdc9f2ef25d2
Autor:
F. van Dijk, Henderik W. Frijlink, Wouter L. J. Hinrichs, Naomi Teekamp, Leonie Beljaars, Yong Ook Kim, Klaas Poelstra, Detlef Schuppan, Peter Olinga, Rob Steendam, Johan Zuidema, Eduard Post
Publikováno v:
Journal of Controlled Release, 269, 258-265. Elsevier Bedrijfsinformatie b.v.
Liver fibrogenesis is associated with excessive production of extracellular matrix by myofibroblasts that often leads to cirrhosis and consequently liver dysfunction and death. Novel protein-based antifibrotic drugs show high specificity and efficacy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86410ba16a2d67547771a5fdefd42a23
https://research.rug.nl/en/publications/5cfdb613-f355-4af0-828c-44a265783b79
https://research.rug.nl/en/publications/5cfdb613-f355-4af0-828c-44a265783b79
Autor:
Sergio Rodriguez, Rob Steendam, Arjen H. Petersen, Ruud A. Bank, Jurjen Zandstra, Gert J. Veldhuis, Eliane R. Popa, Marike van Beuge, A. A. R. Lathuile, Johan Zuidema, Luisa F. Duque, Mark Staal
Publikováno v:
Pharmaceutical Research, 32(10), 3238-3247. SPRINGER/PLENUM PUBLISHERS
Pharmaceutical Research
Pharmaceutical Research
Purpose The increasing prevalence and treatment costs of kidney diseases call for innovative therapeutic strategies that prevent disease progression at an early stage. We studied a novel method of subcapsular injection of monodisperse microspheres, t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d29d61969b386c9233c765e1fe8f475
https://doi.org/10.1007/s11095-015-1700-8
https://doi.org/10.1007/s11095-015-1700-8
Autor:
Christine Hiemstra, Rob Steendam, Milica Stanković, Johan Zuidema, Henderik W. Frijlink, Wouter L. J. Hinrichs, Hans de Waard
Publikováno v:
International Journal of Pharmaceutics, 480(1-2), 73-83. Elsevier Bedrijfsinformatie b.v.
In this study, water-swellable multiblock copolymers composed of semi-crystalline poly(ϵ-caprolactone) [PCL] blocks and amorphous blocks consisting of poly( d , l -lactide) (PDLLA) and poly(ethylene glycol) (PEG) [PDLLA–PEG] were synthesized. The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bca66af4e994f810b4a2d80d5e7954a6
https://doi.org/10.1016/j.ijpharm.2015.01.007
https://doi.org/10.1016/j.ijpharm.2015.01.007
Autor:
Johan Zuidema, Anneke Neijt
Publikováno v:
Written Language and Literacy, 20, 1, pp. 52-79
Written Language and Literacy, 20, 52-79
Written Language and Literacy, 20, 52-79
The BasisSpellingBank is the first lexicon where the spellings and pronunciations of words are documented explicitly and separately for all relevant word parts. Unlike earlier descriptions of Dutch orthography in terms of rules and underlying forms,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5962b56c4bfa33711dd65f242395bf6e
https://hdl.handle.net/2066/179927
https://hdl.handle.net/2066/179927
Autor:
Hans de Waard, Milica Stanković, Johan Zuidema, Christine Hiemstra, Henderik W. Frijlink, Wouter L. J. Hinrichs, Rob Steendam
Publikováno v:
European Journal of Pharmaceutical Sciences, 49(4), 578-587. ELSEVIER SCIENCE BV
Parenteral protein delivery requires preservation of the integrity of proteins and control over the release kinetics. In order to preserve the integrity, parenteral protein delivery formulations typically need to be processed at low temperatures. The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9500c933892af84361d8f87ee90cc08
https://doi.org/10.1016/j.ejps.2013.05.011
https://doi.org/10.1016/j.ejps.2013.05.011