DNA Physical Properties and Nucleosome Positions Are Major Determinants of HIV-1 Integrase Selectivity.

Autor: Monica Naughtin, Zofia Haftek-Terreau, Johan Xavier, Sam Meyer, Maud Silvain, Yan Jaszczyszyn, Nicolas Levy, Vincent Miele, Mohamed Salah Benleulmi, Marc Ruff, Vincent Parissi, Cédric Vaillant, Marc Lavigne

Publikováno v: PLoS ONE, Vol 10, Iss 6, p e0129427 (2015)

Retroviral integrases (INs) catalyse the integration of the reverse transcribed viral DNA into the host cell genome. This process is selective, and chromatin has been proposed to be a major factor regulating this step in the viral life cycle. However

Externí odkaz: https://doaj.org/article/c7cf239038bd474bba473401f2b665c5

TOX4 and NOVA1 Proteins Are Partners of the LEDGF PWWP Domain and Affect HIV-1 Replication

Autor: Yves Jacob, Pierre Charneau, Marc Lavigne, Francesca Di Nunzio, Mehdi Morchikh, Johan Xavier, Monica Naughtin

Publikováno v: PLoS ONE
PLoS ONE, Public Library of Science, 2013, 8, pp.81217-81217. ⟨10.1371/journal.pone.0081217.s005⟩
PLoS ONE, 2013, 8, pp.81217-81217. ⟨10.1371/journal.pone.0081217.s005⟩
PLoS ONE, Vol 8, Iss 11, p e81217 (2013)

International audience; PWWP domains are involved in the chromatin attachment of several proteins. They bind to both DNA and proteins and their interaction with specific histone methylation marks define them as a new class of histone code readers. Th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13eedb96cbb9b0015001f5118092dd01
https://hal-pasteur.archives-ouvertes.fr/pasteur-01416848/document