Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Johan V. Swinnen"'
Autor:
Shuncong Wang, Xin Pang, Frederik de Keyzer, Yuanbo Feng, Johan V. Swinnen, Jie Yu, Yicheng Ni
Publikováno v:
Acta Neuropathologica Communications, Vol 11, Iss 1, Pp 1-12 (2023)
Abstract Automatic segmentation of rodent brain tumor on magnetic resonance imaging (MRI) may facilitate biomedical research. The current study aims to prove the feasibility for automatic segmentation by artificial intelligence (AI), and practicabili
Externí odkaz:
https://doaj.org/article/7f8d77b286a542a38e10cea2116f4f83
Autor:
Odeta Meçe, Diede Houbaert, Maria-Livia Sassano, Tania Durré, Hannelore Maes, Marco Schaaf, Sanket More, Maarten Ganne, Melissa García-Caballero, Mila Borri, Jelle Verhoeven, Madhur Agrawal, Kathryn Jacobs, Gabriele Bergers, Silvia Blacher, Bart Ghesquière, Mieke Dewerchin, Johan V. Swinnen, Stefan Vinckier, María S. Soengas, Peter Carmeliet, Agnès Noël, Patrizia Agostinis
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-18 (2022)
Autophagy is essential to endothelial cell homeostasis. Here the authors show that lipophagy in LEC supports fatty acid oxidation to sustain a mitochondrial-Prox1 gene expression circuit and promote response of LEC to lymphangiogenic mediators.
Externí odkaz:
https://doaj.org/article/6f053768112c4a3e957fc921d9943221
Therapy-induced lipid uptake and remodeling underpin ferroptosis hypersensitivity in prostate cancer
Autor:
Kaylyn D. Tousignant, Anja Rockstroh, Berwyck L. J. Poad, Ali Talebi, Reuben S. E. Young, Atefeh Taherian Fard, Rajesh Gupta, Tuo Zang, Chenwei Wang, Melanie L. Lehman, Johan V. Swinnen, Stephen J. Blanksby, Colleen C. Nelson, Martin C. Sadowski
Publikováno v:
Cancer & Metabolism, Vol 8, Iss 1, Pp 1-21 (2020)
Abstract Background Metabolic reprograming, non-mutational epigenetic changes, increased cell plasticity, and multidrug tolerance are early hallmarks of therapy resistance in cancer. In this temporary, therapy-tolerant state, cancer cells are highly
Externí odkaz:
https://doaj.org/article/c6e2a3ea96274cda8079bc82f329c973
Autor:
Chloé Wilkin, Megan Colonval, Jonas Dehairs, Nathalie Esser, Margaud Iovino, Marco A. Gianfrancesco, Marjorie Fadeur, Johan V. Swinnen, Nicolas Paquot, Jacques Piette, Sylvie Legrand-Poels
Publikováno v:
Nutrients, Vol 13, Iss 10, p 3461 (2021)
(1) Background: Obesity and type 2 diabetes have been suspected to impact both intrinsic metabolism and function of circulating immune cells. (2) Methods: To further investigate this immunometabolic modulation, we profiled the phospholipidome of the
Externí odkaz:
https://doaj.org/article/148b9aa1424b4253beaf148f6daed9b8
Autor:
Shuncong Wang, Lei Chen, Yuanbo Feng, Johan V. Swinnen, Charles Jonscher, Chantal Van Ongeval, Yicheng Ni
Publikováno v:
Cancers; Volume 14; Issue 7; Pages: 1608
The epidemiology and associated potential heterogeneity of synchronous lung metastasis (sLM) have not been reported at a population-based level. Cancer patients with valid information about sLM status in the Surveillance, Epidemiology, and End Result
Autor:
Marco A, Gianfrancesco, Jonas, Dehairs, Laurent, L'homme, Gaëtan, Herinckx, Nathalie, Esser, Olivia, Jansen, Yvette, Habraken, Cédric, Lassence, Johan V, Swinnen, Mark H, Rider, Jacques, Piette, Nicolas, Paquot, Sylvie, Legrand-Poels
Publikováno v:
Biochimica et biophysica acta. Molecular and cell biology of lipids. 1864(7)
NLRP3 inflammasome plays a key role in Western diet-induced systemic inflammation and was recently shown to mediate long-lasting trained immunity in myeloid cells. Saturated fatty acids (SFAs) are sterile triggers able to induce the assembly of the N