Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Johan Tisserand"'
Autor:
Laura Gonzalez-Cano, Jens Christian Schwamborn, Ingeborg Menzl, Sarah Nicklas, Johan Tisserand
Publikováno v:
Mol Neurobiol
Molecular Neurobiology
Molecular Neurobiology
Parkinson’s disease (PD) is the second most common neurodegenerative disorder. Accumulating evidences suggest that PD might have a strong neurodevelopmental component. Among the genetic cases, mutations in the leucine-rich repeat kinase 2 (LRRK2) a
Autor:
Philippe Lucarelli, Johan Tisserand, Jens Christian Schwamborn, Christian Jaeger, Amy C. Harms, Deborah Gérard, Enrico Glaab, Kathrin Hemmer, Xiaobing Qing, Emanuel Berger, Lasse Sinkkonen, Thomas Hankemeier, Silvia Bolognin, Paul Antony, Sarah Louise Nickels, Jonas Walter, Thomas Sauter, Rashi Halder, Christine Klein, Javier Jarazo
Publikováno v:
Parkinsonism & Related Disorders
Parkinsonism & Related Disorders, 67, 48-55. ELSEVIER SCI LTD
Parkinsonism & Related Disorders, 67, 48-55. ELSEVIER SCI LTD
Parkinson's disease (PD) is a multifactorial disorder with complex etiology. The most prevalent PD associated mutation, LRRK2-G2019S is linked to familial and sporadic cases. Based on the multitude of genetic predispositions in PD and the incomplete
Autor:
S. Bonvalot, Jean-Yves Scoazec, Olivier Bouché, Bruno Landi, J.-M. Coindre, P. Cervera, A. Le Cesne, J.-Y. Blay, Michael Heinrich, Pierre-Paul Bringuier, Johan Tisserand, M. P. Buisine, Geneviève Monges, P. Aegerter, J.F. Emile, P. Samb, S. Brahimi, A. Gauthier, Christopher L. Corless, Isabelle Hostein, J. L. Pretet, L. Doucet, Jean-Christophe Sabourin, Agnès Neuville
Publikováno v:
Medical oncology and tumor pharmacotherapy
Medical oncology and tumor pharmacotherapy, Springer-Verlag;Humana Press, 2011, epub ahead of print. 〈10.1007/s12032-011-0074-y〉
Medical oncology and tumor pharmacotherapy, Springer-Verlag;Humana Press, 2011, epub ahead of print. ⟨10.1007/s12032-011-0074-y⟩
Medical oncology and tumor pharmacotherapy, Springer-Verlag;Humana Press, 2011, epub ahead of print. 〈10.1007/s12032-011-0074-y〉
Medical oncology and tumor pharmacotherapy, Springer-Verlag;Humana Press, 2011, epub ahead of print. ⟨10.1007/s12032-011-0074-y⟩
International audience; Gastrointestinal stromal tumors (GISTs) are the most common human sarcoma. Most of the data available on GISTs derive from retrospective studies of patients referred to oncology centers. The MolecGIST study sought to determine
Autor:
Doulaye Dembélé, Régine Losson, Pierre Chambon, Johan Tisserand, Christelle Thibault, Konstantin Khetchoumian
Publikováno v:
Journal of Biological Chemistry. 286:33369-33379
Recent genetic studies in mice have established that the nuclear receptor coregulator Trim24/Tif1α suppresses hepatocarcinogenesis by inhibiting retinoic acid receptor α (Rara)-dependent transcription and cell proliferation. However, Rara targets r
Autor:
Camille Stephan-Otto Attolini, Ivan Garcia-Bassets, Oscar Reina, Roman Kessler, Laura Coch, Fernando Azorín, Joan Font-Burgada, Johan Tisserand
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
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© 2015 Macmillan Publishers Limited. All rights reserved. dDsk2 is a conserved extraproteasomal ubiquitin receptor that targets ubiquitylated proteins for degradation. Here we report that dDsk2 plays a nonproteolytic function in transcription regula
Autor:
Régine Losson, Benjamin Herquel, Johan Tisserand, Marius Teletin, Khalid Ouararhni, Konstantin Khetchoumian
Publikováno v:
Cell Cycle
Cell Cycle, Taylor & Francis, 2008, 7 (23), pp.3647-52
ResearcherID
Cell Cycle, 2008, 7 (23), pp.3647-52
Cell Cycle, Taylor & Francis, 2008, 7 (23), pp.3647-52
ResearcherID
Cell Cycle, 2008, 7 (23), pp.3647-52
International audience; Retinoic acid (RA), the active derivative of vitamin A, is an important signaling molecule that controls various developmental processes and influence the proliferation and differentiation of a variety of cell types. RA exerts
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b26b886f897395eb068e7923d990138
https://www.hal.inserm.fr/inserm-00350903
https://www.hal.inserm.fr/inserm-00350903
Autor:
Johan Tisserand, Christine Dennefeld, Konstantin Khetchoumian, Pierre Chambon, Mihaela Ignat, Manuel Mark, Régine Losson, Marius Teletin
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2008, 105 (7), pp.2598-603. ⟨10.1073/pnas.0712030105⟩
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2008, 105 (7), pp.2598-603. ⟨10.1073/pnas.0712030105⟩
Calcification of arteries is a major risk factor for cardiovascular mortality in humans. Using genetic approaches, we demonstrate here that the transcriptional intermediary factor 1α (TIF1α), recently shown to function as a tumor suppressor in muri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e07df1890821da3dae3ad92033776d6
https://hal.archives-ouvertes.fr/hal-00282567
https://hal.archives-ouvertes.fr/hal-00282567
Autor:
Doulaye Dembélé, Anas Fadloun, Isabelle Michel, Irwin Davidson, Gabrielle Mengus, Dominique Kobi, Johan Tisserand, Laurence Delacroix, Aurélie Lardenois, Régine Losson
Publikováno v:
Oncogene
Oncogene, Nature Publishing Group, 2008, 27 (4), pp.477-89. ⟨10.1038/sj.onc.1210657⟩
Oncogene, Nature Publishing Group, 2008, 27 (4), pp.477-89. ⟨10.1038/sj.onc.1210657⟩
To evaluate the role of murine TFIID subunit TAF4 in activation of cellular genes by all-trans retinoic acid (T-RA), we have characterized the T-RA response of taf4(lox/-) and taf4(-/-) embryonic fibroblasts. T-RA regulates almost 1000 genes in taf4(
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f45f516ee62eb7e8593c0d5a2a582ab
https://hal.archives-ouvertes.fr/hal-00282573
https://hal.archives-ouvertes.fr/hal-00282573
Autor:
Johan Tisserand, Daniel Metzger, Pierre Chambon, Benjamin Herquel, Florence Cammas, Marius Teletin, Mihaela Ignat, Christelle Thibault, Konstantin Khetchoumian, Thierry Lerouge, Manuel Mark, Jessica Zucman-Rossi, Régine Losson
Publikováno v:
Nature Genetics
Nature Genetics, Nature Publishing Group, 2007, 39 (12), pp.1500-6. ⟨10.1038/ng.2007.15⟩
Nature Genetics, 2007, 39 (12), pp.1500-6. ⟨10.1038/ng.2007.15⟩
Nature Genetics, Nature Publishing Group, 2007, 39 (12), pp.1500-6. 〈10.1038/ng.2007.15〉
Nature Genetics, Nature Publishing Group, 2007, 39 (12), pp.1500-6. ⟨10.1038/ng.2007.15⟩
Nature Genetics, 2007, 39 (12), pp.1500-6. ⟨10.1038/ng.2007.15⟩
Nature Genetics, Nature Publishing Group, 2007, 39 (12), pp.1500-6. 〈10.1038/ng.2007.15〉
Hepatocellular carcinoma (HCC) is a major cause of death worldwide. Here, we provide evidence that the ligand-dependent nuclear receptor co-regulator Trim24 (also known as Tif1alpha) functions in mice as a liver-specific tumor suppressor. In Trim24-n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72304472b4423dfa31b3bc5e54bf7989
https://hal.archives-ouvertes.fr/hal-00206236
https://hal.archives-ouvertes.fr/hal-00206236