Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Johan Pansegrouw"'
Autor:
Trevor Khaba, Andrea Olga Papadopoulos, Thandeka Nkosi, Sifundo Nxele, Thandekile Ngubane, Ismail Jajbhay, Johan Pansegrouw, Zaza M. Ndhlovu
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionStudying diseased human tissues offers better insights into the intricate interactions between pathogens and the human host. In conditions such as HIV and cancers, where diseases primarily manifest in tissues, peripheral blood studies are
Externí odkaz:
https://doaj.org/article/01aa2430acaa406abdf464ada98acc7e
Autor:
Bongiwe Mahlobo, Faatima Laher, Werner Smidt, Funsho Ogunshola, Trevor Khaba, Thandeka Nkosi, Anele Mbatha, Thandekile Ngubane, Krista Dong, Ismail Jajbhay, Johan Pansegrouw, Zaza M. Ndhlovu
Publikováno v:
BMC Immunology, Vol 23, Iss 1, Pp 1-19 (2022)
Abstract Background HIV eradication efforts have been unsuccessful partly due to virus persistence in immune sanctuary sites such as germinal centres within lymph node (LN) tissues. Recent evidence suggests that LNs harbour a novel subset of regulato
Externí odkaz:
https://doaj.org/article/44ea8b47cf83442abec00ae4b385cecd
Autor:
Omolara O. Baiyegunhi, Jaclyn Mann, Trevor Khaba, Thandeka Nkosi, Anele Mbatha, Funsho Ogunshola, Caroline Chasara, Nasreen Ismail, Thandekile Ngubane, Ismail Jajbhay, Johan Pansegrouw, Krista L. Dong, Bruce D. Walker, Thumbi Ndung’u, Zaza M. Ndhlovu
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-13 (2022)
Despite antiretroviral therapy, HIV often persists in tissue sanctuary sites. In this work, authors investigate HIV persistence and T cell responses in lymph node biopsies obtained from individuals who initiated antiretroviral therapy in Fiebig stage
Externí odkaz:
https://doaj.org/article/50e73a5e9c94475094bccd50e686c5cb
Autor:
Funsho J. Ogunshola, Werner Smidt, Anneta F. Naidoo, Thandeka Nkosi, Thandekile Ngubane, Trevor Khaba, Omolara O. Baiyegunhi, Bongiwe Mahlobo, Sam Rasehlo, Namani Ngema, Ismail Jajbhay, Krista L. Dong, Veron Ramsuran, Johan Pansegrouw, Thumbi Ndung’u, Bruce D. Walker, Tulio de Oliveria, Zaza M. Ndhlovu
Publikováno v:
Blood Advances. 6:1904-1916
CD8+ T cells play an important role in HIV control. However, in human lymph nodes (LNs), only a small subset of CD8+ T cells express CXCR5, the chemokine receptor required for cell migration into B-cell follicles, which are major sanctuaries for HIV
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0798d0ff69522fca50d5bdc3a74e238
https://doi.org/10.1182/bloodadvances.2021006001
https://doi.org/10.1182/bloodadvances.2021006001
Autor:
Ismail Jajbhay, Thandekile Ngubane, Trevor Khaba, Funsho Ogunshola, Anele Mbatha, Nasreen Ismail, Thandeka Nkosi, Krista L. Dong, Thumbi Ndung'u, Johan Pansegrouw, Omolara Baiyegunhi, Bruce Walker, Jaclyn K. Mann, Zaza Mtine Ndhlovu, Caroline Chasara
HIV persistence in tissue sites despite ART is a major barrier to HIV cure. Detailed studies of HIV infected cells and immune responses in native lymph node (LN) tissue environment is critical for gaining insight into immune mechanisms impacting HIV
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e98a25ded4a614c3b8d80afada09ee01
https://doi.org/10.21203/rs.3.rs-1061787/v1
https://doi.org/10.21203/rs.3.rs-1061787/v1
Autor:
Omolara O. Baiyegunhi, Jaclyn Mann, Trevor Khaba, Thandeka Nkosi, Anele Mbatha, Funsho Ogunshola, Caroline Chasara, Nasreen Ismail, Thandekile Ngubane, Ismail Jajbhay, Johan Pansegrouw, Krista L. Dong, Bruce D. Walker, Thumbi Ndung’u, Zaza M. Ndhlovu
Publikováno v:
Nature Communications
HIV persistence in tissue sites despite ART is a major barrier to HIV cure. Detailed studies of HIV-infected cells and immune responses in native lymph node tissue environment is critical for gaining insight into immune mechanisms impacting HIV persi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8196a279d502566ae52aebebc6e664d6
https://pubmed.ncbi.nlm.nih.gov/35831418
https://pubmed.ncbi.nlm.nih.gov/35831418
Autor:
Krista L. Dong, Johan Pansegrouw, Zaza Mtine Ndhlovu, Anneta Naidoo, Werner Smidt, Tulio de Oliveria, Thandekile Ngubane, Omolara Baiyegunhi, Funsho Ogunshola, Bruce D. Walker, Trevor Khaba, Veron Ramsuran, Thandeka Nkosi, Ismail Jajbhay, Sam Rasehlo, Thumbi Ndung'u
CD8+ T cells play an important role in viral and tumour control. However, in human lymph nodes (LNs), only a small subset of CD8+ T cells called follicular CD8+ T cells (fCD8s) expresses CXCR5, the chemokine receptor required for cell migration into
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::526c22d6814dc67050674964c62415cd
https://doi.org/10.1101/2020.07.17.208470
https://doi.org/10.1101/2020.07.17.208470