Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Johan P. Zeelen"'
Autor:
Gianna Triller, Evi P. Vlachou, Hamidreza Hashemi, Monique van Straaten, Johan P. Zeelen, Yosip Kelemen, Carly Baehr, Cheryl L. Marker, Sandra Ruf, Anna Svirina, Monica Chandra, Katharina Urban, Anastasia Gkeka, Sebastian Kruse, Andreas Baumann, Aubry K. Miller, Marc Bartel, Marco Pravetoni, C. Erec Stebbins, F. Nina Papavasiliou, Joseph P. Verdi
Publikováno v:
Cell Reports, Vol 42, Iss 2, Pp 112049- (2023)
Summary: Poorly immunogenic small molecules pose challenges for the production of clinically efficacious vaccines and antibodies. To address this, we generate an immunization platform derived from the immunogenic surface coat of the African trypanoso
Externí odkaz:
https://doaj.org/article/c7ecefeb83cd43648db62b9d9e7b1931
Autor:
Alexander Hempelmann, Laura Hartleb, Monique van Straaten, Hamidreza Hashemi, Johan P. Zeelen, Kevin Bongers, F. Nina Papavasiliou, Markus Engstler, C. Erec Stebbins, Nicola G. Jones
Publikováno v:
Cell Reports, Vol 37, Iss 5, Pp 109923- (2021)
Summary: The dense variant surface glycoprotein (VSG) coat of African trypanosomes represents the primary host-pathogen interface. Antigenic variation prevents clearing of the pathogen by employing a large repertoire of antigenically distinct VSG gen
Externí odkaz:
https://doaj.org/article/c3acb4d7657a4e0b8cad190d14971cdf
Autor:
Monica Chandra, Sara Đaković, Konstantina Foti, Johan P. Zeelen, Monique van Straaten, Francisco Aresta-Branco, Eliane Tihon, Nicole Lübbehusen, Thomas Ruppert, Lucy Glover, F. Nina Papavasiliou, C. Erec Stebbins
Publikováno v:
PLOS Neglected Tropical Diseases. 17:e0011093
During infection of mammalian hosts, African trypanosomes thwart immunity using antigenic variation of the dense Variant Surface Glycoprotein (VSG) coat, accessing a large repertoire of several thousand genes and pseudogenes, and switching to antigen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::62eeed87f43de65401c03b5b146ed61a
https://doi.org/10.1371/journal.pntd.0011093
https://doi.org/10.1371/journal.pntd.0011093
Autor:
Alexander, Hempelmann, Laura, Hartleb, Monique, van Straaten, Hamidreza, Hashemi, Johan P, Zeelen, Kevin, Bongers, F Nina, Papavasiliou, Markus, Engstler, C Erec, Stebbins, Nicola G, Jones
Publikováno v:
Cell Reports, Vol 37, Iss 5, Pp 109923-(2021)
Summary: The dense variant surface glycoprotein (VSG) coat of African trypanosomes represents the primary host-pathogen interface. Antigenic variation prevents clearing of the pathogen by employing a large repertoire of antigenically distinct VSG gen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::a8736b87e0328d65af8a2351f9b23ec8
https://opus.bibliothek.uni-wuerzburg.de/frontdoor/index/index/docId/27028
https://opus.bibliothek.uni-wuerzburg.de/frontdoor/index/index/docId/27028
Autor:
Sara Đaković, Johan P Zeelen, Anastasia Gkeka, Monica Chandra, Monique van Straaten, Konstantina Foti, Janet Zhong, Evi P Vlachou, Francisco Aresta-Branco, Joseph P Verdi, F Nina Papavasiliou, C Erec Stebbins
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 17, Iss 9, p e0011621 (2023)
Long-term immune evasion by the African trypanosome is achieved through repetitive cycles of surface protein replacement with antigenically distinct versions of the dense Variant Surface Glycoprotein (VSG) coat. Thousands of VSG genes and pseudo-gene
Externí odkaz:
https://doaj.org/article/2a7c6745a9b94c0cacb4fc4bd7e1493b