Zobrazeno 1 - 10
of 446
pro vyhledávání: '"Johan M Kros"'
Improving the characterization of endothelial progenitor cell subsets by an optimized FACS protocol.
Publikováno v:
PLoS ONE, Vol 12, Iss 9, p e0184895 (2017)
The characterization of circulating endothelial progenitor cells (EPCs) is fundamental to any study related to angiogenesis. Unfortunately, current literature lacks consistency in the definition of EPC subsets due to variations in isolation strategie
Externí odkaz:
https://doaj.org/article/133106e0d574465fac92c99c527f9177
Autor:
Rute M.S.M. Pedrosa, Johan M. Kros, Benjamin Schrijver, Cor Berrevoets, Rute B. Marques, Casper C.H.J. van Eijck, Reno Debets, PieterJ.M. Leenen, Willem A. Dik, DanaA.M. Mustafa
Publikováno v:
Heliyon, Vol 10, Iss 16, Pp e36598- (2024)
The appearance of brain metastasis is the most serious complication of breast cancer with mostly fatal outcomes. To reach the brain, tumor cells need to pass the blood-brain barrier (BBB). The molecular mechanisms underlying penetration of the BBB ar
Externí odkaz:
https://doaj.org/article/91b48a283cba4dc88e4fa1450d84f079
Autor:
Dana A M Mustafa, Anieta M Sieuwerts, Marcel Smid, Vania de Weerd, Marcel van der Weiden, Marion E Meijer-van Gelder, John W M Martens, John A Foekens, Johan M Kros
Publikováno v:
PLoS ONE, Vol 10, Iss 12, p e0144097 (2015)
Gene expression profiling of tumors is a successful tool for the discovery of new cancer biomarkers and potential targets for the development of new therapeutic strategies. Reliable profiling is preferably performed on fresh frozen (FF) tissues in wh
Externí odkaz:
https://doaj.org/article/0f912b0987de47b283065af2a91fc30f
Autor:
Lara Andreoli, Catalina Berca, Sonja Katz, Maryna Korshevniuk, Ritchie M. Head, Kristel Van Steen, TranSYS Consortium, Kris Dierickx, Federico Melograna, Zuqi Li, Giada Lalli, Johan M. Kros, Shiva Najjary, Damjana Rozman, Andrew Walakira, Alexander Skupin, Elle Wilson, Francisco X. Real, Benno Schwikowski, Behnam Yousefi, Nataša Pržulj, Katarina Mihajlovic, Elisabeth B. Binder, Nahid Taheri, Anastasiia Hryhorzhevska, Lude Franke, George P. Patrinos, Kariofyllis Karamperis, Oscar Lao, Vitor A. P. Martins dos Santos, Christina Olsen, Ritchie Head
Publikováno v:
Frontiers in Medicine, Vol 11 (2024)
IntroductionIn the evolving healthcare landscape, precision medicine's rise necessitates adaptable doctoral training. The European Union has recognized this and promotes the development of international, training-focused programmes called Innovative
Externí odkaz:
https://doaj.org/article/33e1667ff3424246bdd333e44becb2c0
Autor:
Linda B Bralten, Stephan Nouwens, Christel Kockx, Lale Erdem, Casper C Hoogenraad, Johan M Kros, Michael J Moorhouse, Peter A Sillevis Smitt, Peter van der Spek, Wilfred van Ijcken, Andrew Stubbs, Pim J French
Publikováno v:
PLoS ONE, Vol 6, Iss 7, p e22000 (2011)
A common and histologically well defined subtype of glioma are the oligodendroglial brain tumors. Approximately 70% of all oligodendrogliomas have a combined loss of the entire 1p and 19q chromosomal arms. This remarkably high frequency suggests that
Externí odkaz:
https://doaj.org/article/e99b8474a2a34603829260532f3abc87
Autor:
Shiva Najjary, Johan M. Kros, Bruno H. Stricker, Rikje Ruiter, Yu Shuai, Robert Kraaij, Kristel Van Steen, Peter van derSpek, Casper H. J. Van Eijck, M. Arfan Ikram, Shahzad Ahmad
Publikováno v:
Cancer Medicine, Vol 13, Iss 3, Pp n/a-n/a (2024)
Abstract The immune response–gut microbiota interaction is implicated in various human diseases, including cancer. Identifying the link between the gut microbiota and systemic inflammatory markers and their association with cancer will be important
Externí odkaz:
https://doaj.org/article/5c6d3b511d7247668c577ceb0cb7ec86
Autor:
Shiva Najjary, Johan M. Kros, Willem de Koning, Disha Vadgama, Karishma Lila, Janina Wolf, Dana A. M. Mustafa
Publikováno v:
Acta Neuropathologica Communications, Vol 11, Iss 1, Pp 1-12 (2023)
Abstract Metastases in the brain are the most severe and devastating complication of cancer. The incidence of brain metastasis is increasing. Therefore, the need of finding specific druggable targets for brain metastasis is demanding. The aim of this
Externí odkaz:
https://doaj.org/article/e95eb251c5384fe3ae7a61741557fb1d
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionThe incidence of brain metastases in cancer patients is increasing, with lung and breast cancer being the most common sources. Despite advancements in targeted therapies, the prognosis remains poor, highlighting the importance to investig
Externí odkaz:
https://doaj.org/article/270604d075a549e693cb32fb468421f8
Autor:
Fatemeh Arzanforoosh, Maaike Van der Velden, Avery J. L. Berman, Sebastian R. Van der Voort, Eelke M. Bos, Joost W. Schouten, Arnaud J. P. E. Vincent, Johan M. Kros, Marion Smits, Esther A. H. Warnert
Publikováno v:
Cancers, Vol 16, Iss 1, p 138 (2023)
Cerebral hypoxia significantly impacts the progression of brain tumors and their resistance to radiotherapy. This study employed streamlined quantitative blood-oxygen-level-dependent (sqBOLD) MRI to assess the oxygen extraction fraction (OEF)—a mea
Externí odkaz:
https://doaj.org/article/8cd2d07b9ed042d3bb5e6bba26fd27d1
Autor:
Fatemeh Arzanforoosh, Sebastian R. van der Voort, Fatih Incekara, Arnaud Vincent, Martin Van den Bent, Johan M. Kros, Marion Smits, Esther A. H. Warnert
Publikováno v:
Cancers, Vol 15, Iss 7, p 2135 (2023)
In this study, we used the vessel size imaging (VSI) MRI technique to characterize the microvasculature features of three subtypes of adult-type diffuse glioma lacking enhancement. Thirty-eight patients with confirmed non-enhancing glioma were catego
Externí odkaz:
https://doaj.org/article/9a4da53e2c484c9ea69c89944c713f93