Zobrazeno 1 - 10
of 67
pro vyhledávání: '"Johan Kemmink"'
Autor:
Lukas Pfeifer, Stefano Crespi, Charlotte N. Stindt, Pieter van der Meulen, Johan Kemmink, Ruud M. Scheek, Michiel F. Hilbers, Wybren J. Buma, Ben L. Feringa
Publikováno v:
Proceedings of the Dynamic Materials, Crystals and Phenomena Conference.
Autor:
Marthe T. C. Walvoort, Ioli Kotsogianni, Nathaniel I. Martin, Liubov Yakovlieva, Johan Kemmink, Franziska Koller, Thomas M. Wood, Juergen Lassak
Publikováno v:
Chemical Science
Chemical Science, 12(4), 1560-1567
Chemical Science, 12(4), 1560-1567. ROYAL SOC CHEMISTRY
Chemical Science, 12(4), 1560-1567
Chemical Science, 12(4), 1560-1567. ROYAL SOC CHEMISTRY
For canonical asparagine glycosylation, the primary amino acid sequence that directs glycosylation at specific asparagine residues is well-established. Here we reveal that a recently discovered bacterial enzyme EarP, that transfers rhamnose to a spec
Autor:
Thomas M, Wood, Matthieu R, Zeronian, Ned, Buijs, Kristine, Bertheussen, Hanieh K, Abedian, Aidan V, Johnson, Nicholas M, Pearce, Martin, Lutz, Johan, Kemmink, Tjalling, Seirsma, Leendert W, Hamoen, Bert J C, Janssen, Nathaniel I, Martin
Publikováno v:
Chemical science. 13(10)
The continued rise of antibiotic resistance is a global concern that threatens to undermine many aspects of modern medical practice. Key to addressing this threat is the discovery and development of new antibiotics that operate by unexploited modes o
Autor:
Sijbren Otto, Jim Ottelé, Pieter van der Meulen, Dávid Komáromy, Johan Kemmink, Ankush Sood, Bin Liu, Friso S. Aalbers, Giuseppe Portale, Guillermo Monreal Santiago, Vittorio Saggiomo, Theodora D. Tiemersma-Wegman, Ivana Marić
In this manuscript we describe how, by taking a systems approach, complex energy landscapes of supramolecular assemblies can be navigated using stoichiometry to control, with remarkable selectivity, which assembly gets populated. The perhaps counteri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8ee3deda4ee10a1d2e7c3a7d29cad49
https://doi.org/10.26434/chemrxiv.10117343
https://doi.org/10.26434/chemrxiv.10117343
Autor:
Eefjan Breukink, Johan Kemmink, Rianne A. G. Harmsen, Dirk T. S. Rijkers, Nourdin Ghalit, Rob M. J. Liskamp
Publikováno v:
Tetrahedron. 70:7691-7699
The bacteria-specific membrane component lipid II is essential for bacterial cell wall synthesis. A tricyclic nisin mimic was designed and synthesized in which both thioether moieties were mimicked by an alkane-bridge, as well as the introduction of
Autor:
Laurens H. J. Kleijn, Sabine F. Oppedijk, Johan Kemmink, Nathaniel I. Martin, Peter 't Hart, Gerjan de Bruin
Publikováno v:
Organic and Biomolecular Chemistry
Organic and Biomolecular Chemistry, 12(6), 913-918
Organic and Biomolecular Chemistry, 12(6), 913-918
The calcium-dependent lipopeptide antibiotics represent a promising new class of antimicrobials for use in combating drug-resistant bacteria. At present, daptomycin is the only such lipopeptide used clinically and displays potent antimicrobial activi
Publikováno v:
Chemistry - A European Journal. 19:16923-16927
Autor:
Arwin J. Brouwer, Helmus van de Langemheen, Rob M. J. Liskamp, Johan Kemmink, John A. W. Kruijtzer
Publikováno v:
The Journal of Organic Chemistry. 77:10058-10064
The synthesis of cyclic peptides containing a thioester handle using a sulfo-click linker is reported. These cyclic peptides can be coupled to N-terminal cysteine-containing constructs via native chemical ligation. A successful application of a cycli
Autor:
Monique P. C. Mulder, John A. W. Kruijtzer, Rob M. J. Liskamp, Johan Kemmink, Roland J. Pieters, Eefjan Breukink
Publikováno v:
Bioorganic & Medicinal Chemistry. 19:6505-6517
Echinocandins are a novel class of macrocyclic antifungal peptides that act by inhibiting the β-(1,3)-D-glucan synthase complex, which is not present in mammalian cells. Due to the large number of hydroxyl groups present in these complex macrocyclic
Publikováno v:
ChemBioChem. 12:1626-1653
Despite their enormous diversity in biological function and structure, peptides and proteins are endowed with properties that have induced and stimulated the development of peptidomimetics. Clearly, peptides can be considered as the "stem" of a phylo