Zobrazeno 1 - 10
of 109
pro vyhledávání: '"Johan Kamphuis"'
Autor:
Hans E. Schoemaker, Wilhelmus H.J. Boesten, Quirinus B. Broxterman, Eric C. Roos, Bernard Kaptein, Will J.J. van den Tweel, Johan Kamphuis, Emmo M. Meijer, Floris P.J.T. Rutjes
Publikováno v:
CHIMIA, Vol 51, Iss 6 (1997)
Aminopeptidase- and amidase-based methods for the production of enantiomerically pure amino acids, intermediates for pharmaceuticals and agrochemicals, are discussed. Furthermore, enzymatic syntheses of the dipeptide sweetener aspartame and semisynth
Externí odkaz:
https://doaj.org/article/c682ce31a4784b23a95dda9ab6badbe1
Autor:
A. Dautant, Fernando Formaggio, M. Pantano, W. H. J. Boesten, Claudio Toniolo, André Aubry, Marco Crisma, Gian Maria Bonora, Hans E. Schoemaker, Johan Kamphuis, D. Bayeul
Publikováno v:
Recueil des Travaux Chimiques des Pays-Bas. 113:29-34
Homochiral (αMe)Leu/Ala and Leu/Ala model peptides were synthesized by solution methods and fully characterized. A solution conformational analysis of the tripeptides was carried out using FT-IR absorption and 1H NMR. The crystal-state structure of
Autor:
Hans E. Schoemaker, S. Polinelli, Francesco Lelj, Claudio Toniolo, Marco Crisma, Johan Kamphuis, E. M. Meijer, W. H. J. Boesten, A. Rosa, B. Klajc, Gian Maria Bonora, P. Grimaldi
Publikováno v:
International Journal of Peptide and Protein Research. 38:242-252
Conformational energy computations on Ac-L-(alpha Me)Val-NHMe indicate that turns and right-handed helical structures are particularly stable conformations for this chiral C alpha-methyl, C alpha-alkylglycyl residue. We have synthesized and character
Autor:
Marco Crisma, EM Emmo Meijer, Whj Boesten, Johan Kamphuis, S Polinelli, G. Valle, Hans E. Schoemaker, Claudio Toniolo
Publikováno v:
International Journal of Peptide and Protein Research. 37:521-527
The molecular and crystal structures of one derivative and three model peptides (to the pentapeptide level) of the chiral C alpha,alpha-disubstituted glycine C alpha-methyl, C alpha-isopropylglycine [(alpha Me)Val] have been determined by X-ray diffr
Autor:
Claudio Toniolo, Johan Kamphuis, B. Kaptein, Fernando Formaggio, Quirinus B. Broxterman, V. Moretto, Cristina Peggion, Marco Crisma
Publikováno v:
The Journal of Peptide Research. 58:317-324
We synthesized using solution-phase methods three analogs of [l-Leu11-OMe] trichogin GA IV, a membrane active synthetic precursor of the lipopeptaibol antibiotic in which the N-terminal n-octanoyl group and each of the three Aib residues in positions
Autor:
Johan Kamphuis, Cristina Peggion, Bernard Kaptein, Quirinus B. Broxterman, Eric Mossel, Claudio Toniolo, Fernando Formaggio, Marco Crisma
Publikováno v:
The Journal of Peptide Research. 55:262-269
Using a chemo-enzymatic approach we prepared the highly lipophilic, chiral, Calpha-methylated alpha-amino acid (alphaMe)Aun. Two series of terminally protected model peptides containing either D-(alphaMe)Aun in combination with Aib or L-(alphaMe)Aun
Autor:
Marco Crisma, Quirinus B. Broxterman, Claudio Toniolo, Bernard Kaptein, Johan Kamphuis, Cristina Peggion, Fernando Formaggio, Claudia Piazza
Publikováno v:
Letters in Peptide Science. 7:9-16
We synthesized by solution-phase methods the naturally occurring, 10-amino acid residue lipopeptaibol antibiotics trikoningins KBI and KBII, and the [l-Iva1] KB analogue, in which the amino acid in position 1 is different, with the aim at investigati
Publikováno v:
Oléagineux, Corps gras, Lipides, Vol 15, Iss 4, Pp 262-264 (2008)
GLA rich oils are used mainly for their antiinflammatory effects. As inflammation plays a role in a large number of diseases, GLA can also affect a large number of diseases/conditions. Clinical studies have shown that GLA regulates transepidermal wat
Publikováno v:
Scopus-Elsevier
Autor:
Bernard Bodo, Quirinus B. Broxterman, Evaristo Peggion, Fernando Formaggio, Johan Kamphuis, Stefano Mammi, Claudio Toniolo, Vania Monaco, Marco Crisma, Elsa Locardi, Sylvie Rebuffat
Publikováno v:
Scopus-Elsevier
We have synthesized by solution-phase methods two analogues of the 11-residue lipopeptaibol antibiotic trichogin GA IV in which the N-terminal n-octanoyl group is replaced either by an N-acetylated 2-amino-2-methyl-L-undecanoic acid or by an N-acetyl